Definition: A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
zorubicin [ RP 22050,Rubidazone,daunomycin benzoylhydrazone,zorubicin hydrochloride, (L-xylo)-(2S-cis)-isomer,zorubicin, (L-arabino)-(2S-cis)-isomer,zorubicine ] RN given refers to (L-xylo)-(2S-cis)-isomer; structure
Antibiot Chemotherap 23:255;1978; Biochem Pharm 26(3):215;1977; Biochem Pharm 27(8):1221;1978; Biochim Biophys Acta 1979;565(1):13; Br J Cancer 34(1):64;1976; Brit Med J 4(838):468;1972; Bull Can 65(1):19;1978; Cancer 37(2):653;1976; Cancer Chemotherap Rpts part 1-59(2):301;1975; Cancer Res 37:4623;1977; Cancer Treat Rep 1979;63(11-12):1701; Cancer Treat Rep 1979;63(11-12):1771; Cancer Treat Rep 62(10):1599;1978; Cancer Treat Rep 62(6):935;1978; Cancer Treat Rep 62(7):1053;1978; J Antibiot 1979;32(19):1038; J Histochem Cytochem 1979;27(12):1655; J Med Chem 21(8):732;1978; J Nat Can Inst 60(2):279;1978; Lancet II (8080):104;1978