Definition: A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Other names Desmethylimipramine; Novartis Brand of Desipramine Hydrochloride; Norpramin; Desipramine Hydrochloride; Demethylimipramine; Aventis Brand of Desipramine Hydrochloride; Aventis Behring Brand of Desipramine Hydrochloride; Apotex Brand of Desipramine Hydrochloride; Apo-Desipramine; Rh+¦ne Poulenc Rorer Brand of Desipramine Hydrochl; Nu Pharm Brand of Desipramine Hydrochloride; Hydrochloride, Desipramine; ratio-Desipramine; Temmler Brand of Desipramine Hydrochloride; Rh+¦ne-Poulenc Rorer Brand of Desipramine Hydrochl; Ratiopharm Brand of Desipramine Hydrochloride; Pharmascience Brand of Desipramine Hydrochloride; Petylyl; Pertrofran; Pertofrane