telithromycin [ Aventis brand of telithromycin,HMR 3647,HMR-3647,HMR3647,Ketek,RU 66647,RU-66647 ] a ketolide; semisynthetic derivative of erythromycin with cycling of the C11-12 positions to form a carbamate ring to avoid acquired resistance to macrolides; binds 70S bacterial rRNA, specifically to