Definition: Enzymes that catalyze the exohydrolysis of 1,4-alpha-glucosidic linkages with release of alpha-glucose. Deficiency of alpha-1,4-glucosidase may cause GLYCOGEN STORAGE DISEASE TYPE II.
defic/: consider also GLYCOGEN STORAGE DISEASE TYPE II
GAA protein, human [ rhGAA,Genzyme brand of Recombinant human alglucosidase alfa,LYAG protein, human,Myozyme,acid alpha-glucosidase, human,acid maltase, human,alglucosidase alfa,glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II), human,lysosomal alpha-glucosidase, human,recombinant human acid alpha-glucosidase ] Defects in the gene for this protein cause glycogen storage disease II, also known as Pompe disease, RefSeq NM_000152