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triptolide

under Diterpenes
More information in Books or onNLM PubMed
More on Diterpenes Definition: Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.  GEN; prefer specifics    Other names Norditerpenes; Diterpenes, Labdane; Diterpenes, Cembrane; Labdane Diterpenes; Cembrane Diterpenes; Norditerpenoids; Labdanes; Diterpenoids; Cembranes
SubstanceCAS Registry & nameCategoriesSourceDrugs*
triptolide [ PG490 ]
  also has antiangiogenic activity; a phytogenic antineoplastic agent; a tri-epoxide phenanthrene from Chinese herb, Tripterygium wilfordii; structure
38748-32-2   *Diterpenes *Phenanthrenes Epoxy Compounds Anti-Inflammatory Agents, Non-Steroidal Tripterygium
Pharma Action Antispermatogenic Agents; Immunosuppressive Agents; Antineoplastic Agents, Alkylating
J Am Chem Soc 94(20):7194;1972; J Org Chem 42(15):2569;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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