encyclopedia of medical concepts
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bestatin

under Leucine
More information in Books or onNLM PubMed
More on Leucine Definition: An essential branched-chain amino acid important for hemoglobin formation.  /biosyn /defic /physiol permitted    Other names Leucine, L Isomer; L-Isomer Leucine; Leucine, L-Isomer; L-Leucine
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bestatin [ 3-amino-2-hydroxy-4-phenylbutyryl-L-leucine,bestatin, (D-Leu)-(R-(R*,R*))-isomer,bestatin, (D-Leu)-(R-(R*,S*))-isomer,bestatin, (D-Leu)-(S-(R*,S*))-isomer,bestatin, (L-Leu)-(R-(R*,R*))-isomer,bestatin, (L-Leu)-(R-(R*,S*))-isomer,bestatin, (L-Leu)-(S-(R*,R*))-isomer,bestatin, (L-Leu)-(S-(R*,S*))-isomer, hydrochloride,ubenimex ]
  growth inhibitor; RN given refers to ((L-Leu)-(S-(R*,S*)))-isomer; structure 		58970-76-6 (3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine  Leucine/*analogs & derivatives Aminopeptidases/antagonists & inhibitors
Pharma Action Adjuvants, Immunologic; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Immunologic Factors; Protease Inhibitors; Anti-HIV Agents 		Immunology 1979;38(1):75; Adv Exp Med Biol 1979;120B:332; Antibiotics Chemother 24:10;1978; Arch Biochem Biophys 177(1):196;1976; Biochem Biophys Res Commun 76(2):526;1977; Biochem Pharmacol 1979;28(20):3131; Cell Immunol 40(2):247;1978; J Antibiotics 29(1):97-100;1976; J Antibiotics 29(5):600;1976; J Med Chem 20(4):510;1977; Jpn J Antibiotics 30suppl:121;1977; Lloydia 40(1):67;1977; Prog Biochem Pharmacol 11:24;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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