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decitabine

under Azacitidine
More information in Books or onNLM PubMed
More on Azacitidine Definition: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.      Other names Azacytidine; NSC102816; NSC 102816; 5 Azacytidine; Vidaza; Pharmion Brand of Azacitidine; NSC-102816; 5-Azacytidine Drugs: VIDAZA
SubstanceCAS Registry & nameCategoriesSourceDrugs*
decitabine [ 2'-deoxy-5-azacytidine,5-aza-2'-deoxycytidine,5-azadeoxycytidine,5-deoxyazacytidine,Dacogen,NSC 127716,NSC-127716,decitabine mesylate ]
  structure given in first source 		2353-33-5   Azacitidine/*analogs & derivatives Myelodysplastic Syndromes DNA Modification Methylases/antagonists & inhibitors
Pharma Action Antimetabolites, Antineoplastic; Enzyme Inhibitors; Teratogens 		Biochem Pharmacol 28(8):1443;1979; Cancer Res 1979;39(10):3822; Cancer Res 37:1636;1977; Cancer Res 38(9):2673;1978; FEBS Lett 78(2):244;1977; JNCI 1979;63(4):1035; Neoplasma 25(4):385;1978 DACOGEN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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