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beta-lapachone

under Naphthoquinones
More information in Books or onNLM PubMed
More on Naphthoquinones Definition: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.      Other names Naphthazarins; Naphthalenediones
SubstanceCAS Registry & nameCategoriesSourceDrugs*
beta-lapachone [ ARQ 501 ]
  inhibitor of reverse transcriptase & DNA polymerase; structure; inhibitor of DNA topoisomerase 		4707-32-8 3,4-dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione  *Naphthoquinones
Pharma Action Anti-Infective Agents; Radiation-Sensitizing Agents; Reverse Transcriptase Inhibitors 		An Acad Bras Cienc 50(4):598;1978; Ann Trop Med Parasitol 72(6):523;1978; Antimicrob Agents Chemother 14(4):630; Arch Biochem Biophys 186(2):292;1978; Biochem J 175(2):431;1978; Eur J Biochem 84:197;1978; Exp Parasitol 42:142;1977; Lancet 2(8101):1190;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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