O-deacetyl platelet activating factor (definition)

encyclopedia of medical concepts

O-deacetyl platelet activating factor

under Platelet Activating Factor

More information in Books or on

Definition: A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.

Other names Phosphorylcholine, Acetyl Glyceryl Ether; PAF-Acether; Acetyl Glyceryl Ether Phosphorylcholine; AGEPC; Platelet Activating Substance; PAF Acether; Factor, Platelet Activating; Aggregating Factor, Platelet; 1 Alkyl 2 acetyl sn glycerophosphocholine; Thrombocyte Aggregating Activity; Platelet-Activating Substance; Platelet Aggregation Enhancing Factor; Platelet Aggregating Factor; 1-Alkyl-2-acetyl-sn-glycerophosphocholine

Substance	CAS Registry & name	Categories	Source	Drugs*
O-deacetyl platelet activating factor [ lyso-PAF,1-O-alkylglyceryl-3-phosphorylcholine,1-alkyl-sn-glycero-3-phosphocholine,2-lyso PAF-acether,deacetyl-PAF,lyso-platelet activating factor ] released from leukocytes	0	Platelet Activating Factor/analogs & derivatives Inflammation Mediators Pharma Action* Immunologic Factors	Proc Natl Acad Sci USA 1980;77(12):7019

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link

Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy