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methylazoxymethanol

under Methylazoxymethanol Acetate
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More on Methylazoxymethanol Acetate Definition: The aglycone of CYCASIN. It acts as a potent carcinogen and neurotoxin and inhibits hepatic DNA, RNA, and protein synthesis.      Other names Acetate, Methylazoxymethanol; (Methyl-ONN-azoxy)methanol Acetate
SubstanceCAS Registry & nameCategoriesSourceDrugs*
methylazoxymethanol [ methazoxymethanol ]
  a neuroteratogen; reacts with guanine residues of DNA & RNA forming 7-methylguanine adduct products; carcinogenicity probably related to biological decomposition into methyldiazonium ion, the ultimate 		590-96-5   Methylazoxymethanol Acetate/*analogs & derivatives Mitosis/drug effects
Pharma Action Alkylating Agents; Carcinogens; Teratogens 		Cancer Biochem Biophys 1981;5(2):119

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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