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polyclonal B cell activator

under alpha-Macroglobulins
More information in Books or onNLM PubMed
More on alpha-Macroglobulins Definition: Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.      Other names alpha-Macrofetoproteins; alpha 2-Glucoproteins; alpha 2-Acute Phase Globulins; Slow alpha 2-Macroglobulins; alpha2 Macroglobulin; alpha Macroglobulins; alpha Macrofetoproteins; alpha Macrofetoprotein; alpha 2-Macroglobulins, Slow; alpha 2-Globulin, Slow; alpha 2 Macroglobulin; alpha 2 Glucoproteins; alpha 2 Glucoprotein; alpha 2 Acute Phase Globulins; alpha 2 Acute Phase Globulin; alpha 1-Protein, Acute-Phase; alpha 1 Macroglobulin; alpha 1 Acute Phase Protein; alpha 1 Acute Phase Globulin; Slow alpha 2 Macroglobulins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
polyclonal B cell activator
  factor found in alpha(2)-macroglobulin fraction of serum of patients with rheumatoid arthritis which produces polyclonal B cell activation; combination of rheumatoid factor & polyclonal B cell activat 		0   *alpha-Macroglobulins
Pharma Action Mitogens 		Proc Inst Med Chic 1981;34(3):75

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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