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nafamostat

under Guanidines
More information in Books or onNLM PubMed
More on Guanidines Definition: A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.  do not confuse with GUANINE   
SubstanceCAS Registry & nameCategoriesSourceDrugs*
nafamostat [ 6'-amidino-2-naphthyl 4-guanidinobenzoate,FUT 175,FUT-175,nafamostat dihydrochloride,nafamostat mesilate,nafamostat mesylate,nafamstat mesilate ]
  inhibitor of trypsin, plasmin, pancreatic kallikrein, plasma kallikrein & thrombin; strongly inhibits esterolytic activities of C1r & C1 esterase complement-mediated hemolysis; antineoplastic; RN give 		81525-10-2 Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dihydrochloride  *Guanidines Fibrinolysin/antagonists & inhibitors Kallikreins/antagonists & inhibitors
Pharma Action Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Protease Inhibitors; Trypsin Inhibitors; Serine Proteinase Inhibitors; Complement Inactivating Agents 		Biochim Biophys Acta 1981;661(2):342

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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