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ICI 154129

under Enkephalin, Leucine
More information in Books or onNLM PubMed
More on Enkephalin, Leucine Definition: One of the endogenous pentapeptides with morphine-like activity. It differs from MET-ENKEPHALIN in the LEUCINE at position 5. Its first four amino acid sequence is identical to the tetrapeptide sequence at the N-terminal of BETA-ENDORPHIN.  DF: LEU ENKEPHALIN    Other names Leucine Enkephalin; Leu Enkephalin; Enkephalin, 5-Leucine; 5 Leucine Enkephalin; Leu-Enkephalin; Leu(5)-Enkephalin; 5-Leucine Enkephalin
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ICI 154129 [ ICI 154129, (R-(R*,S*))-isomer,ICI 154129, (S-(R*,R*))-isomer,ICI-154129,M 154,129,M-154,129,N,N-bis(allyl)-Tyr-Gly-Gly-psi-methylthio-Phe-Leu,N,N-bis(allyl)-tyrosyl-glycyl-glycyl-psi-methylthio-phenylalanyl-leucine ]
  RN given refers to cpd without isomeric designation
83420-94-4 Glycinamide, N,N-di-2-propenyl-L-tyrosyl-N-(2-((2-((1-carboxy-3-methylbutyl)amino)-2-oxo-1-(phenylmethyl)ethyl)thio)ethyl)-, (S-(R*,R*))  Enkephalin, Leucine/*analogs & derivatives
Pharma Action Narcotic Antagonists
Life Sci 1982;31(12-13):1259

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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