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muramylNAc-Ala-isoGln-Lys-tripeptide-PE

under Phosphatidylethanolamines
More information in Books or onNLM PubMed
More on Phosphatidylethanolamines Definition: Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to an ethanolamine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and ethanolamine and 2 moles of fatty acids.  /biosyn /physiol permitted    Other names Ethanolamine Phosphoglycerides; Cephalins; Phosphoglycerides, Ethanolamine; Ethanolamineglycerophospholipids
SubstanceCAS Registry & nameCategoriesSourceDrugs*
muramylNAc-Ala-isoGln-Lys-tripeptide-PE [ CGP 19835 A,CGP 19853A lipid,CGP-19835A,MLV 19835,N-acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethanolamine,mifamurtide,muramyl tripeptide phosphatidylethanolamine,muramyl tripeptide phosphatidylethanolamine, monosodium salt,muramyl tripeptide phosphatidylethanolamine, sodium salt,muramyl tripeptide-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine conjugate,muramyl tripeptide-1,2-dipalmitoylphosphatidylethanolamine conjugate,muramylNAc-Ala-isoGln-Lys-tripeptide-phosphatidylethanolamine ]
  protects mice against herpes simplex virus type 2; structure given in first source; RN refers to L-Alaninamide,(R)-isomer; a macrophage activator; called muramyl tripeptide but that term is ambiguous,
83461-56-7 L-Alaninamide, N-(N-acetylmuramoyl)-L-alanyl-D-alpha-glutaminyl-N-(4-hydroxy-10-oxo-7-((1-oxohexadecyl)oxy)-3,5,9-trioxa-4-phosphapentacos-1-yl)-, P-oxide, (R)  *Phosphatidylethanolamines Acetylmuramyl-Alanyl-Isoglutamine/*analogs & derivatives
Pharma Action Adjuvants, Immunologic; Immunologic Factors
Prog Clin Biol Res 1982;102(A):347

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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