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tiludronic acid

under Diphosphonates
More information in Books or onNLM PubMed
More on Diphosphonates Definition: Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.      Other names Bisphosphonates
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tiludronic acid [ Skelid,(4-chlorophenyl)thiomethylene bisphosphonic acid,(chloro-4-phenyl)thiomethylene biphosphonate,(chloro-4-phenyl)thiomethylene bisphosphonate,Cl2SMBP,tiludronate,tiludronate disodium ]
  a bone resorption inhibitor; an antihypercalcemic agent; used in the tratment of Paget's disease; used in the treatment and prevention of osteoporosis; structure given in first source
89987-06-4   *Diphosphonates
Pharma Action Bone Density Conservation Agents
Rev Med Liege 1988;43(24):799 SKELID

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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