Definition: An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)
mycophenolate mofetil [ Cellcept,Mycophenolate Sodium,Myfortic,RS 61443,RS-61443,Sodium Mycophenolate,mycophenolate mofetil hydrochloride,mycophenolic acid morpholinoethyl ester ] mycophenolic acid that is chemically altered by the addition of morpholinoethylester; selective and reversible inhibitor of inosine monophosphate dehydrogenase
