Definition: A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.
Other names Protirelin Ferring Brand; Protirelin Aventis Brand; Protirelin Abbott Brand; Prem, TRH; Abbott38579; Abbott 38579; Thyrotropin-Releasing Hormone Tartrate; Thyrotropin-Releasing Factor; Thyroliberin TRH Merck; Thypinone; TRH Prem; TRH Ferring; Stimu-TSH; Relefact TRH; Protirelin Tartrate (1:1); Proterelin Tartrate; Novartis Brand of Protirelin; Merck Brand of Protirelin; Henning Berlin Brand of Protirelin; Ferring Brand of Protirelin
TA 0910 [ (1-methyl-4,5-dihydroorotyl)-histidyl-prolinamide,TA-0910,taltirelin hydrate ] structure given in first source; has central nervous system actions; RN given refers to (S)-isomer; RN for cpd without isomeric designation not available 8/90