Definition: A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
lenograstim [ Euprotin,Amrad Brand of Lenograstim,Aventis Brand of Lenograstim,Chugai Brand of Lenograstim,Granocyte,Prasfarma Brand of Lenograstim,Rh+¦ne-Poulenc Rorer Brand of Lenograstim,lenograstim, Component 1,lenograstim, Component 2 ] amino acid and carbohydrate sequence given in first source; RN given is for parent compound; Component 1 and Component 2 differ by absence or presence of Neu5Ac in 2-6 linkage to GalNAc side chain
