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tenofovir

under Phosphonic Acids
More information in Books or onNLM PubMed
More on Phosphonic Acids Definition: Inorganic or organic derivatives of phosphonic acid with the general formula ROP(OH)2 or RP(=O)(OH)2. The tautomeric form of this compound (P(OH)3) is PHOSPHOROUS ACIDS. Nucleoside phosphonates have a phosphate-carbon bond that is more resistant to enzymatic cleavage than the normal phosphate-oxygen bond.  do not confuse with PHOSPHINIC ACIDS; for nucleoside phosphonates coordinate with PURINES or PYRIMIDINES    Other names Esters, Phosphonic Acid; Acids, Phosphonic; Acid Esters, Phosphonic; Phosphonic Acid Esters; Phosphonates
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tenofovir [ (R)-9-(2-phosphonylmethoxypropyl)adenine,9-(2-phosphonomethoxypropyl)adenine,9-(2-phosphonylmethoxypropyl)adenine,9-(2-phosphonylmethoxypropyl)adenine, (+-)-isomer,9-(2-phosphonylmethoxypropyl)adenine, (R)-isomer,9-(2-phosphonylmethoxypropyl)adenine, (S)-isomer,9-PMPA ] 107021-12-5   *Phosphonic Acids Adenine/*analogs & derivatives
Pharma Action Reverse Transcriptase Inhibitors; Anti-HIV Agents 		Lancet 1995 Dec 2;346(8988):1482

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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