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TNFR-Fc fusion protein

under Immunoglobulin G
More information in Books or onNLM PubMed
More on Immunoglobulin G Definition: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.  gammopathy: coordinate IMMUNOGLOBULIN G (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA, follow text    Other names IgG; Gamma Globulin, 7S; GT, Immunoglobulin; 7S Gamma Globulin; Polyglobin; Immunoglobulin GT; IgG4; IgG3; IgG2B; IgG2A; IgG2; IgG1; IgG(T); Allerglobuline
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TNFR-Fc fusion protein [ TNR 001,Enbrel,Immunex brand of etanercept,TNF receptor type II-IgG fusion protein,TNR-001,TNT receptor fusion protein,TNTR-Fc,Wyeth brand of etanercept,etanercept,recombinant human dimeric TNF receptor type II-IgG fusion protein ]
  reduces tumor necrosis factor activity, as well as cytokine, chemokine, and stress hormone release; used to treat SPONDYLITIS, ANKYLOSING
185243-69-0   *Immunoglobulin G *Receptors, Tumor Necrosis Factor Arthritis, Rheumatoid Recombinant Fusion Proteins Tumor Necrosis Factor-alpha
Pharma Action Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Agents; Immunosuppressive Agents; Antirheumatic Agents; Immunologic Factors
J Immunol 1995 Nov 15;155(10):5038-45 ENBREL

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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