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everolimus

under Sirolimus
More information in Books or onNLM PubMed
More on Sirolimus Definition: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.      Other names I2190A; I 2190A; AY 22989; AY 22 989; Wyeth Brand of Sirolimus; Rapamune; I-2190A; AY 22-989; Rapamycin Drugs: RAPAMUNE
SubstanceCAS Registry & nameCategoriesSourceDrugs*
everolimus [ 40-O-(2-hydroxyethyl)-rapamycin,Certican,RAD 001,RAD001,SDZ RAD,SDZ-RAD ]
  a rapamycin analog; structure in first source 		159351-69-6   Sirolimus/*analogs & derivatives
Pharma Action Immunosuppressive Agents 		Transplantation 1997 Jul 15;64(1):36-42 AFINITOR; ZORTRESS

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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