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alefacept

under Recombinant Fusion Proteins
More information in Books or onNLM PubMed
More on Recombinant Fusion Proteins Definition: Recombinant proteins produced by the GENETIC TRANSLATION of fused genes formed by the combination of NUCLEIC ACID REGULATORY SEQUENCES of one or more genes with the protein coding sequences of one or more genes.  do not confuse with MEMBRANE FUSION PROTEINS; VIRAL FUSION PROTEINS; MUTANT CHIMERIC PROTEINS; or ONCOGENE PROTEINS, FUSION    Other names Fusion Proteins, Recombinant; Proteins, Recombinant Hybrid; Proteins, Recombinant Fusion; Proteins, Recombinant Chimeric; Recombinant Hybrid Proteins; Recombinant Chimeric Proteins; Hybrid Proteins, Recombinant; Chimeric Proteins, Recombinant
SubstanceCAS Registry & nameCategoriesSourceDrugs*
alefacept [ Amevive,Biogen brand of alefacept,LFA-3 IgG(1) fusion protein,LFA-3 IgG1 fusion protein ]
  1-92-LFA-3 antigen/immunoglobulin G1 fusion homodimer; used to treat plaque psoriasis; a biologic response modifier; amino acid sequence in first source
222535-22-0   *Recombinant Fusion Proteins Psoriasis
Pharma Action Dermatologic Agents
Clin Pharmacol Ther 2000 Nov;68(5):580 AMEVIVE

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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