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Acetamides

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Definition: Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.     
Examples 2-Acetylaminofluorene; Allylisopropylacetamide; Benzeneacetamides; Iodoacetamide; Oseltamivir; Piracetam; Thioacetamide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-amino-N-(2-(4-(3-(2-trifluoromethylphenothiazin-10-yl)propyl)piperazin-1-yl)-ethyl)acetamide  0   *Acetamides *Phenothiazines. Allergy Asthma Proc. 2011 Sep-Oct;32(5):359-65.
2-(4-((4-(acetylamino)-4'-chloro-(1,1'-biphenyl)-2-yl)methoxy)phenyl)-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid  0   *Acetamides *Benzimidazoles RNA Replicase/antagonists & inhibitors. Antiviral Res. 2012 Jan;93(1):30-8.
KX2 329  0   *Acetamides *Pyridines src-Family Kinases/antagonists & inhibitors. Neurosci Res. 2011 Dec;71(4):348-54.
N-(6-fluoro-4-phenoxypyridin-3-yl)-N-(2-methoxybenzyl)acetamide  0   *Acetamides *Aminopyridines Fluorine Radioisotopes. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4819-22.
N-(3,5-dimethylphenyl)-2-((5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl)sulfanyl)acetamide  0   *Acetamides *Triazoles Choline Kinase/antagonists & inhibitors. Oncogene 2011 Jul 28;30(30):3370-80
N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide  0   *Acetamides *Triazines. J Med Chem 2011 Jul 14;54(13):4427-45
N-(2-(7-(cyclohexylmethyl)-1,6-dihydro-2H-indeno(5,4-b)furan-8-yl)ethyl)acetamide  0   *Acetamides *Benzofurans Receptors, Melatonin/agonists. J Med Chem 2011 May 12;54(9):3436-44
10'-bis(acetamido)-ethane-bis(1,4,7-tri(methylene phosphonic acid)-1,4,7,10-tetraazacyclododecane)  0   *Acetamides *Organophosphorus Compounds. Bioconjug Chem. 2011 Feb 16;22(2):244-55
(13-(2-(butylamino)-2-oxoacetamido)tridec-8(Z)-enoic acid)  0   *Acetamides *Oleic Acids. Br J Pharmacol. 2011 Feb;162(4):897-907
2-(3-benzoyl-4-hydroxy-1,1-dioxido-2H-benzo(e)(1,2)thiazin-2-yl)-N- (3-(trifluoromethyl)phenyl)acetamide  0   *Acetamides *Thiazines. Chem Pharm Bull (Tokyo). 2011;59(1):46-52
N-(3-(4-(6-isopropoxypyridin-3-yloxy)phenyl)-1-methylpropyl)acetamide  0   *Acetamides *Pyridines Acetyl-CoA Carboxylase/antagonists & inhibitors. J Med Chem 2010 Dec 23;53(24):8679-87
S-(acetamidomethyl)mercapturic acid  0   *Acetamides Acetylcysteine/*analogs & derivatives. J Chromatogr B Analyt Technol Biomed Life Sci 2010 Oct 1;878(27):2515-9
2-cyano-N-(4,6-dimethoxypyrimidin-2-yl)acetamide  0   *Acetamides *Pyrimidines. Acta Crystallogr C. 2010 Oct;66(Pt 10):o521-3
2-(4-benzylpiperazin-1-yl)-N-(3,4-dihydro-2(1H)-quinolinone-6-yl)acetamide  0   *Acetamides *Quinolones. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4464-7
2,2,2-trifluoro-N-(1a,2,7,7a-tetrahydronaphtho(2,3-b)oxiren-3-yl)acetamide  0   *Acetamides *Naphthalenes. Acta Crystallogr C. 2010 Sep;66(Pt 9):o475-8
KT 15073  0   *Acetamides *Aniline Compounds. Bioorg Med Chem Lett 2010 Feb 1;20(3):461-7
N-((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenyl)acetamide  0   *Acetamides. Exp Eye Res. 2010 Aug;91(2):153-61
2-(2-(4-bromo-2-fluorobenzyl)-1,2-dihydro-1-oxophthalazin-4-yl)-N-(2,6-dimethylphenyl)acetamide  0   *Acetamides *Phthalazines. Chem Biol Drug Des. 2010 Apr;75(4):381-91
N-(2-(phenyl)-8-methylpyrazolo(4,3-e)(1,2,4)triazolo(1,5-c)pyrimidin-5-yl)phenylacetamide  0   *Acetamides *Heterocyclic Compounds, 3-Ring Receptor, Adenosine A3/antagonists & inhibitors. J Med Chem 2010 Apr 22;53(8):3361-75
2-cyano-2-isonitrosoacetamide  0   *Acetamides *Nitriles. Dalton Trans. 2010 Jan 21;39(3):749-64
alpha-(methylthio)acetamide  0   *Acetamides. J Phys Chem A. 2010 Jan 14;114(1):105-16
2-pyrrolidin-1-yl-N-(4-(4-(2-pyrrolidin-1-yl-acetylamino)benzyl)phenyl)acetamide  0   *Acetamides *Pyrrolidines. J Comput Chem 2009 Dec;30(16):2594-601
N-(4-methylphenyl)-2,2-dichloroacetamide  0   *Acetamides. Spectrochim Acta A Mol Biomol Spectrosc 2009 Oct 15;74(3):607-16
N-(2-methylphenyl)-2,2-dichloroacetamide  0   *Acetamides. Spectrochim Acta A Mol Biomol Spectrosc 2009 Oct 15;74(3):607-16
N-benzyl-N-methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide  0   *Acetamides *Purines Carbon Radioisotopes. Nucl Med Biol. 2009 Oct;36(7):801-9
N-(2-((3-bromophenyl)-(4-fluorophenyl)amino)ethyl)acetamide  0   *Acetamides *Aniline Compounds Ligands. ChemMedChem 2009 Oct;4(10):1746-55
N-(2-((3-methoxyphenyl)phenylamino)ethyl)acetamide  0   *Acetamides *Aniline Compounds Ligands. ChemMedChem 2009 Oct;4(10):1746-55
N-1-(2-(1-(tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)-5-chlorophenyl)ethyl)acetamide  0   *Acetamides *Pyrrolidines Receptor, Melanocortin, Type 4/agonists. Clin Pharmacol Ther 2009 Dec;86(6):659-66
N-(4-acetyl-2-bromophenyl)-2-(4-(3,4-dichlorophenyl)-1,2,3-selenadiazol-5-ylthio)acetamide  0   *Acetamides *Organoselenium Compounds. Bioorg Med Chem. 2009 Sep 1;17(17):6374-9
2-methoxy-N-((6-(1-methyl-4-(methylamino)-1,6-dihydroimiazo(4,5-d)pyrrolo(2,3-b)pyridin-7-yl)pyridin-2-yl)methyl)acetamide  0   *Acetamides *Heterocyclic Compounds, 3-Ring I-kappa B Kinase/antagonists & inhibitors. J Pharmacol Exp Ther 2009 Nov;331(2):349-60
N-((3R)-1-((6-fluoro-2-naphthyl)methyl)pyrrolidin-3-yl)-2-(1-(2-hydroxybenzoyl)piperidin-4-ylidene)acetamide  0   *Acetamides *Naphthalenes Piperidines. Bioorg Med Chem. 2009 Aug 15;17(16):5989-6002
N-(2-chloropyridin-3-yl)-2-(4-(2,4-dibromophenyl)-1,2,3-thiadiazol-5-ylthio)acetamide  0   *Acetamides *Thiadiazoles. Bioorg Med Chem. 2009 Aug 15;17(16):5920-7
N,N-dipropyl-(2-(8-(2-aminoacetamido)-2-(4-chlorophenyl)imidazo(1,2-a)pyridin-3-yl))acetamide  0   *Acetamides *Bicyclo Compounds, Heterocyclic Ligands. J Control Release 2009 Aug 4;137(3):185-95
N,N-di-n-propyl-(2-(6,8-dichloro-2-(4-hydroxyphenyl)imidazo(1,2-a)pyridin-3-yl))acetamide  0   *Acetamides *Bicyclo Compounds, Heterocyclic Ligands. J Control Release 2009 Aug 4;137(3):185-95
albidopyrone  0   *Acetamides *Pyrones. J Antibiot (Tokyo) 2009 Feb;62(2):75-9
N-acetyl-N-(4-(4-methoxyphenyl-3-(3,4,5-trimethoxyphenyl)isoxazol-5-yl)acetamide)  0   *Acetamides *Isoxazoles. Cancer Lett. 2009 Nov 18;285(1):13-22
N,N-diethyl-2-(2-(3-iodo-4-methoxyphenyl)-5,7-dimethylpyrazolo(1,5-a)pyrimidin-3-yl)acetamide  0   *Acetamides *Pyrimidines Iodine Radioisotopes. Biochem Biophys Res Commun 2009 Nov 6;389(1):80-3
N-(4-(5-(3-benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyloxy)phenyl)acetamide  0   *Acetamides *Quinazolinones Receptors, Thyrotropin/agonists. Proc Natl Acad Sci U S A 2009 Jul 28;106(30):12471-6
N-(4-(5-(3-(furan-2-ylmethyl)-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyloxy)phenyl)acetamide  0   *Acetamides *Quinazolinones Receptors, Thyrotropin/agonists. Proc Natl Acad Sci U S A 2009 Jul 28;106(30):12471-6
KT-15087  0   *Acetamides *Vinyl Compounds. Pharmacol Res. 2009 Jun;59(6):414-22
propynyloxypropyl trifluoroacetamide  0   *Acetamides. Nucleic Acids Symp Ser (Oxf) 2008;(52):385-6
N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido(2,3-d)pyrimidin-2-yl)ethyl)-N-pyridin-3-ylmethyl-2-(4-trifluoromethoxyphenyl)acetamide  0   *Acetamides *Pyrimidinones Receptors, CXCR3/antagonists & inhibitors. Drug Metab Dispos 2009 Mar;37(3):502-13
1,3,5,7-tetramethyl-8-phenyl-(4-iodoacetamido)difluoroboradiaza-s-indacene  0   *Acetamides *Heterocyclic Compounds, 3-Ring. J Chromatogr A. 2009 May 1;1216(18):3874-80
1-pyrrolidineacetamide  0   *Acetamides *Pyrrolidines. Acta Pharmacol Sin. 2008 Oct;29(10):1261-7
poly(N-vinylacetamide)  0   *Acetamides *Polyvinyls. J Control Release 2009 Feb 20;134(1):2-10
1-(1-methylsulfonylpyrrol-3-yl)-2-difluoroacetamidopropane-1,3-diol  0   *Acetamides *Pyrroles. Acta Pol Pharm 2009 Jan-Feb;66(1):69-72
N-(naphthalen-2-yl)-N-phenyl-2-(quinolin-8-yloxy)acetamide  0   *Acetamides *Quinolines Ligands. Spectrochim Acta A Mol Biomol Spectrosc 2008 Dec 15;71(4):1461-5
2-(4-(4-cyano-phenoxy)-3,5-dicyclopropyl-1H-pyrazol-1-yl)-N-methylacetamide  0   *Acetamides *Pyrazoles. J Pharmacol Exp Ther 2008 Oct;327(1):58-67
tamiphosphor  0   *Acetamides *Cyclohexenes. Angew Chem Int Ed Engl. 2008;47(31):5788-91
mexiletine acetamide  0   *Acetamides Mexiletine/*analogs & derivatives. Talanta 2008 Mar 15;75(1):239-45
2-cyano-6-fluorophenylacetamide  0   *Acetamides *Nitriles. Bioorg Med Chem Lett. 2008 May 1;18(9):2865-70
3,3,7,7-tetra(N-ethyl-N-benzyl(acetamide)-2-oxymethyl)-5- oxanonane  0   *Acetamides *Benzyl Compounds. J Fluoresc. 2008 Jan;18(1):149-53
N-(2-(4-(aminosulfonyl)phenyl)ethyl)-2-(2-thienyl)acetamide  0   *Acetamides *Sulfhydryl Compounds. Biochemistry. 2008 Jan 8;47(1):490-502
N-(2-methoxybenzyl)-N-(4-phenoxypyridin-3-yl)acetamide  0   *Acetamides *Pyridines. J Med Chem 2008 Jan 10;51(1):17-30
2-(6-chloro-2-(4-iodophenyl)-imidazo(1,2-alpha)pyridin-3-yl)-N-ethyl-N-methyl-acetamide  0   *Acetamides *Pyridines Carbon Radioisotopes. Glia. 2007 Nov 1;55(14):1459-68
4'-acetamidochalcone  0   *Acetamides Chalcone/*analogs & derivatives. Molecules 2007;12(4):896-906
2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide  0   *Acetamides *Pyrazines Prodrugs. J Pharmacol Exp Ther 2007 Sep;322(3):1181-8
2-benzoyl-phenoxy acetamide  0   *Acetamides. Invest New Drugs 2006 Nov;24(6):471-8
1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane  0   *Acetamides *Heterocyclic Compounds, 1-Ring Ligands. Dalton Trans 2006 Jul 21;(27):3291-3
acetamide 45  0   *Acetamides *Indoles. Acta Pharmacol Sin 2005 Dec;26(12):1492-6
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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