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Acetaminophen

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Definition: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.     
Pharmacological Action Analgesics, Non-Narcotic; Antipyretics
Other names Paracetamol; Hydroxyacetanilide; Acetamidophenol; Anacin3; Anacin 3; p-Hydroxyacetanilide; p-Acetamidophenol; Tylenol; N-Acetyl-p-aminophenol; N-(4-Hydroxyphenyl)acetanilide; Panadol; Datril; Anacin-3; Algotropyl; Acetominophen; Acetaco; Acephen; Acamol; APAPDrugs* : INJECTAPAP; ZYDONE; EMPRACET W/ CODEINE PHOSPHATE #3; SEDAPAP; BUCET; TENCON; ACEPHEN; TYLENOL W/ CODEINE NO. 4; ANEXSIA 7.5/650; CODRIX; TYLENOL W/ CODEINE NO. 2; NORCO; CO-GESIC; PHRENILIN; BANCAP; TRIAPRIN; BUTAPAP; ANEXSIA 7.5/325; CAPITAL AND CODEINE; TYLENOL W/ CODEINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
acetaminophen, dextromethorphan, doxylamine succinate, pseudoephedrine drug combination  0   *Acetaminophen *Dextromethorphan *Pseudoephedrine Multi-Ingredient Cold, Flu, and Allergy Medications.
HIFENAC MR  0   *Acetaminophen *Chlorzoxazone Diclofenac/*analogs & derivatives. J Chromatogr Sci 2008 Aug;46(7):649-52
acetaminophen, codeine drug combination  0   *Acetaminophen *Codeine Drug Combinations. Ann Oncol 2008 Jan;19(1):44-8
SELAPINA  0   *Acetaminophen *Amiodarone Drug Combinations. Nihon Kokyuki Gakkai Zasshi 2006 Nov;44(11):858-63
oxycodone-acetaminophen  0   *Acetaminophen *Oxycodone Drug Combinations. PERCOCET
gamma-glutamylcysteinylacetominophen  0   *Dipeptides Acetaminophen/*analogs & derivatives. Toxicol Appl Pharmacol. 2005 Jan 15;202(2):160-71
3'-hydroxyacetaminophen  0   Acetaminophen/*analogs & derivatives. Biotechnol Prog 2003 Nov-Dec;19(6):1632-8
acetaminophen, chlorpheniramine, dextromethorphan, phenylpropanolamine drug combination  0   *Acetaminophen *Chlorpheniramine *Dextromethorphan *Phenylpropanolamine Drug Combinations. Vet Hum Toxicol 2002 Jun;44(3):169-71
4-(nitroxy)butanoic acid 4-acetylaminophenyl ester  0   *Nitrates Acetaminophen/*analogs & derivatives. Dig Liver Dis 2003 May;35 Suppl 2:S49-60
Ultracet  0   *Acetaminophen *Tramadol Drug Combinations. J Mass Dent Soc 2003 Summer;52(2):38-40TRAMADOL HYDROCHLORIDE AND ACETAMINOPHEN; ULTRACET
Night Nurse  0   *Acetaminophen *Dextromethorphan *Phenylpropanolamine *Promethazine Drug Combinations. Eye 2001 Apr;15(Pt 2):248-9
Shin Ruru A  0   *Acetaminophen *Caffeine *Guaiacol *Muramidase Drug Combinations Nonprescription Drugs. J Dermatol 2000 Jun;27(6):401-4
SCP 1  0   Acetaminophen/*analogs & derivatives Saccharin/*analogs & derivatives. Eur J Pharm Biopharm 1998 Nov;46(3):293-7
Myprodol  0   *Acetaminophen *Codeine *Ibuprofen. J Dent Assoc S Afr 1992 Sep;47(9):403-6
acetaminophen, aspirin, caffeine drug combination  0   *Acetaminophen *Aspirin *Caffeine Drug Combinations.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal
J Pharm Pharmacol 1997 Dec;49(12):1260EXCEDRIN (MIGRAINE); ACETAMINOPHEN, ASPIRIN AND CAFFEINE; CODEINE, ASPIRIN, APAP FORMULA NO. 3; ACETAMINOPHEN, ASPIRIN, AND CODEINE PHOSPHATE; CODEINE, ASPIRIN, APAP FORMULA NO. 4; CODEINE, ASPIRIN, APAP FORMULA NO. 2
polyoxyethylene bis(acetaminophen)  0   *Polyethylene Glycols Acetaminophen/*analogs & derivatives. Anal Chem 1997 Jul 15;69(14):2734-41
4-acetylaminophenyl sulfate  0   *Sulfuric Acid Esters Acetaminophen/*analogs & derivatives. Biol Pharm Bull 1997 May;20(5):522-9
3-acetylaminophenyl sulfate  0   *Sulfuric Acid Esters Acetaminophen/*analogs & derivatives. Biol Pharm Bull 1997 May;20(5):522-9
2-acetylaminophenyl sulfate  0   *Sulfuric Acid Esters Acetaminophen/*analogs & derivatives. Biol Pharm Bull 1997 May;20(5):522-9
L 5409709  0   *Acetaminophen *Caffeine *Ibuprofen Drug Combinations. Pain 1997 Apr;70(2-3):253-66
caffeine, codeine, acetaminophen, propyphenazone drug combination  0   *Acetaminophen *Caffeine *Codeine Antipyrine/*analogs & derivatives Drug Combinations.
Pharma Action Analgesics
Zh Neuropatol Psikhiatr Im S S Korsakova 1997;97(4):48-9
PABRON-GOLD  0   *Acetaminophen *Muramidase Codeine/*analogs & derivatives Drug Combinations Common Cold. Nippon Kyobu Shikkan Gakkai Zasshi 1997 Jan;35(1):72-6
4-acryloyloxyacetanilide  86229-44-9   Acetaminophen/*analogs & derivatives. J Biomater Sci Polym Ed 1995;7(6):523-30
acetaminophen, hydrocodone drug combination  0   *Acetaminophen *Hydrocodone Drug Combinations.
Pharma Action Analgesics, Opioid ; Anti-Inflammatory Agents, Non-Steroidal
Anesthesiology 1993 Oct;79(4):857-60VICODIN; VICODIN ES; VICODIN HP
Kinuya-chinnetsu  0   *Acetaminophen *Caffeine Drug Combinations. Chest 1993 Jul;104(1):291-2
N-nitroso-3,5-dinitroacetaminophen  146897-61-2 Acetamide, N-(4-hydroxy-3,5-dinitrophenyl)-N-nitroso  *Nitroso Compounds Acetaminophen/*analogs & derivatives. Biochem Pharmacol 1993 Feb 24;45(4):819-25
acetaminophen-mercapturic acid conjugate  0   *Acetaminophen *Acetylcysteine. Toxicol Appl Pharmacol 1992 Nov;117(1):81-7
acetaminophen cysteinylglycine  116709-74-1   *Dipeptides Acetaminophen/*analogs & derivatives. Toxicol Appl Pharmacol 1991;109(2):305
acetaminophen cysteine  64014-06-8 L-Cysteine, S-(4-(acetylamino)phenyl)  Acetaminophen/*analogs & derivatives Cysteine/*analogs & derivatives. Toxicol Appl Pharmacol 1991;109(2):305
propacetamol  66532-86-3   Acetaminophen/*analogs & derivatives Prodrugs.
Pharma Action Analgesics ; Anti-Inflammatory Agents, Non-Steroidal
Cah Anesthesiol 1989;37(7):521
3-(cystein-S-yl)paracetamol  53446-10-9   Acetaminophen/*analogs & derivatives. Lancet 1990;335(8691):732
acetaminophen, butalbital, caffeine drug combination  0   *Acetaminophen *Barbiturates *Caffeine Drug Combinations.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal
Clin Ther 1987;10(1):69ESGIC; FIORICET W/ CODEINE; TRIAD; ANOQUAN; BUTALIBITAL, ACETAMINOPHEN AND CAFFEINE; FIORICET; FEMCET; PHRENILIN WITH CAFFEINE AND CODEINE; BUTALBITAL, ACETAMINOPHEN AND CAFFEINE; BUTALBITAL, ACETAMINOPHEN, CAFFEINE AND CODEINE PHOSPHATE; MEDIGESIC PLUS; ESGIC-PLUS
acetaminophen hemisuccinate  20675-25-6   Acetaminophen/*analogs & derivatives. Ann Clin Biochem 1988;25(Pt 1):42
4-caprylamidophenol  82568-64-7   Acetaminophen/*analogs & derivatives. Ann Clin Biochem 1988;25(Pt 1):42
Pameton  99126-15-5   *Acetaminophen *Methionine Drug Combinations. Drug Ther Bull 1987;25(25):99
3-methylacetaminophen  16375-90-9   Acetaminophen/*analogs & derivatives. Biochem Pharmacol 1987;36(13):2065
acetaminophen, caffeine, guaifenesin drug combination  0   *Acetaminophen *Caffeine *Guaifenesin Drug Combinations. Act Nerv Super (Praha) 1986;28(2):153
acetaminophen mercapturate  52372-86-8 L-Cysteine, N-acetyl-S-(5-(acetylamino)-2-hydroxyphenyl)  Acetaminophen/*analogs & derivatives. Biochem Pharmacol 1986;35(5):817
N-acetyl-4-benzosemiquinone imine  87015-37-0   Acetaminophen/*analogs & derivatives. Mol Pharmacol 1986;29(2):155
panadol soluble  0   *Acetaminophen *Bicarbonates Drug Combinations. Lancet 1985;2(8455):614
acetaminophen sulfate ester  10066-90-7   Acetaminophen/*analogs & derivatives. Mol Pharmacol 1985;27(6):634
Nyquil  0   *Acetaminophen *Dextromethorphan *Doxylamine *Pseudoephedrine Drug Combinations Nonprescription Drugs. N Engl J Med 1985;313(1):48
2,6-dimethylacetaminophen  6337-56-0 Acetamide, N-(4-hydroxy-2,6-dimethylphenyl)  Acetaminophen/*analogs & derivatives. Thromb Res 1985;38(1):33
Propain  138230-30-5   *Acetaminophen *Caffeine *Codeine *Diphenhydramine Drug Combinations. Br J Clin Pract 1985;39(1):21
Stopayne  0   *Acetaminophen *Codeine *Meprobamate Drug Combinations. S Afr Med J 1985;67(9):325
mersyndol  100216-57-7 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (6aS-(6aalpha,7alpha,8beta,9aalpha))  *Acetaminophen *Codeine *Doxylamine Drug Combinations. Aust Dent J 1984;29(5):300
acetaminophen-cysteine conjugate  0   *Acetaminophen *Cysteine. Clin Chem 1985;31(1):1148
Paedosed  8057-12-3 Acetamide, N-(4-hydroxyphenyl)-, mixt. with 1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one compd. with 2,2,2-trichloro-1,1-ethanediol (1:2)  *Acetaminophen Antipyrine/*analogs & derivatives Drug Combinations Preanesthetic Medication. Anaesthesia 1984;39(10):1039
3-methoxyacetaminophen  3251-55-6   Acetaminophen/*analogs & derivatives. Drug Metab Dispos 1984;12(4):484
SUR 2647  69217-67-0   Acetaminophen/*analogs & derivatives. Eur J Clin Pharmacol 1984;26(5):573
3',5'-dimethylacetaminophen  22900-79-4   Acetaminophen/*analogs & derivatives. J Biol Chem 1984;259(16):10284
acetaminophen, pholcodine, pseudoephedrine drug combination  0   *Acetaminophen *Ascorbic Acid *Dextromethorphan Codeine/*analogs & derivatives Multi-Ingredient Cold, Flu, and Allergy Medications. J Int Med Res 1984;12(2):124
pholcolix  90326-84-4 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-17-methyl-3-(2-(4-morpholinyl)ethoxy)-, (5alpha,6alpha)-, mixt. with (R*,S*)-(+-)-alpha-(1-aminoethyl)benzenemethanol and N-(4-hydroxyphenyl)acetamide  *Acetaminophen *Phenylpropanolamine Codeine/*analogs & derivatives Drug Combinations. Curr Med Res Opin 1983;8(8):594
UP 341,01  0   Acetaminophen/*analogs & derivatives. Ann Chir 1983;37(4):318
rhinasal  89212-58-8 Acetamide, N-(4-hydroxyphenyl)-, mixt. with (R-(R*,S*))-alpha-(1-aminoethyl)benzenemethanol hydrochloride and Trasinanium methanesulfonate  *Acetaminophen *Phenylpropanolamine Drug Combinations. Presse Med 1983;12(27):1725
acetaminophen glucuronide  16110-10-4 beta-D-Glucopyranosiduronic acid, 4-(acetylamino)phenyl  Acetaminophen/*analogs & derivatives. Chem Biol Interact 1983;43(3):283
chloracetadol  15687-05-5 Acetamide, N-(4-(2,2,2-trichloro-1-hydroxyethoxy)phenyl)  Acetaminophen/*analogs & derivatives. Ann Pharm Fr 1982;40(4):365
Paramax  73802-00-3 Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride, mixt. with N-(4-hydroxyphenyl)acetamide  *Acetaminophen *Metoclopramide Drug Combinations. Br J Clin Pract 1982;36(10):359
3-thiomethylparacetamol  37398-23-5 Acetamide, N-(4-hydroxy-3-(methylthio)phenyl)  Acetaminophen/*analogs & derivatives. Clin Pharmacol Ther 24(3):287;1978; Xenobiotica 1982;12(6):381
3-thiomethylparacetamol glucuronide  78180-86-6 beta-D-Glucopyranosiduronic acid, 4-(acetylamino)-2-(methylthio)phenyl  Acetaminophen/*analogs & derivatives. Xenobiotica 1982;12(6):381
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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