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Acetic Acids

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Definition: Acetic acid and its derivatives which may be formed by substitution reactions. Mono- and di-substituted, as well as halogenated compounds have been synthesized.  do not confuse with ACETIC ACID; note X ref ACETIC ACID ESTERS see ACETATES; acetic acid salts   
Examples Acetamides; Acetic Acid; Acetic Anhydrides; Aminooxyacetic Acid; Edetic Acid; Egtazic Acid; Iodoacetic Acid; Nitrilotriacetic Acid; Pentetic Acid; Peracetic Acid; Phosphonoacetic Acid; Trichloroacetic Acid; Trifluoroacetic Acid 		Other names Acids, Acetic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-(4-nitrobenzyl)-1-oxa-4,7,10-triazacyclododecane-N,N'',N'''-triacetic acid  0   *Acetic Acids *Heterocyclic Compounds, 1-Ring Ligands. Bioorg Med Chem. 2012 Jan 15;20(2):978-84.
1-oxa-4,7,10-triazacyclododecane-N,N'',N'''-triacetic acid  0   *Acetic Acids *Heterocyclic Compounds, 1-Ring Ligands. Bioorg Med Chem. 2012 Jan 15;20(2):978-84.
15-hexadecynyloxyacetic acid  0   *Acetic Acids. Bioorg Med Chem. 2012 Jan 15;20(2):650-4.
(2-benzyl-6-carboxy-1-thioxo-1,2,3,4-tetrahydro-beta-carbolin-9-yl)acetic acid  0   *Acetic Acids *Carbolines. Bioorg Med Chem. 2012 Jan 1;20(1):356-67
cysteinyl-phenyl-triaminohexaacetate  0   *Acetic Acids Cysteine/*analogs & derivatives Chelating Agents. J Biomol NMR. 2011 Nov;51(3):329-37.
AZD1981  0   *Acetic Acids *Indoles. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6288-92
2-(2-methyl-4-((1-(6-(4-(trifluoromethyl)phenyl)-2-pyridinyl)pentyl)oxy)phenoxy)acetic acid  0   *Acetic Acids *Pyridines PPAR delta/agonists. Diabetes Obes Metab. 2011 May;13(5):455-64.
(4-chloro-2-((2-fluoro-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid  0   *Acetic Acids *Sulfones. J Med Chem. 2011 Oct 27;54(20):7299-317.
(4-chloro-2-((2-methyl-5-(propylsulfonyl)phenyl)ethynyl)phenoxy)acetic acid  0   *Acetic Acids *Sulfones. J Med Chem. 2011 Oct 27;54(20):7299-317.
CP 544326  0   *Acetic Acids *Sulfonamides Receptors, Prostaglandin E, EP2 Subtype/agonists. Exp Eye Res. 2011 Sep;93(3):256-64.
(1-(4-methyl-1-(6-(trifluoromethyl)-3-pyridinyl)pentyl)-2-(4-(trifluoromethyl)phenyl)-4-piperidinyl)acetic acid  0   *Acetic Acids *Piperidines Amyloid Precursor Protein Secretases. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1306-11.
(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid  0   *Acetic Acids *Tetrazoles Stearoyl-CoA Desaturase/antagonists & inhibitors. J Med Chem 2011 Jul 28;54(14):5082-96
9-anthraceneacetic acid  0   *Acetic Acids *Anthracenes. J Phys Chem B 2010 Sep 2;114(34):11363-9
acetic acid-2-hydroxy-6-(3-oxo-butyl)phenyl ester  0   *Acetic Acids. Res Microbiol. 2010 Jun;161(5):335-45
(4-((3,5-(2-(bis-carboxymethylamino)ethylcarbamoyl)phenylcarbamoyl)methyl)-7,10-bis-carboxymethyl-1,4,7,10-tetraazacyclododec-1-yl)acetic acid  0   *Acetic Acids *Heterocyclic Compounds, 1-Ring. Dalton Trans 2010 Jun 28;39(24):5721-7
2-(3-pyridine)acetic acid  0   *Acetic Acids *Pyridines. Acta Vitaminol 1961 Aug;15:157-61
(1-aminomethyl-3,4-dimethylcyclopentyl)acetic acid  0   *Acetic Acids *Cyclopentanes. Br J Clin Pharmacol 2009 Aug;68(2):174-80
6-fluoroindan-1-acetic acid  0   *Acetic Acids *Indans. Med Chem. 2009 Sep;5(5):468-73
(2-(2,6-dichloro-phenylamino)-phenyl)-acetic acid  0   *Acetic Acids *Aniline Compounds. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Dec;74(5):1209-14
terpenylic acid  0   *Acetic Acids 4-Butyrolactone/*analogs & derivatives. Environ Sci Technol 2009 Sep 15;43(18):6976-82
2,2'-(5,5'-(4,5-dimethoxy-1,2-phenylene)bis(ethyne-2,1-diyl)bis(pyridine-5,2-diyl))bis(methylene)bis((pyridin-2-ylmethyl)azanediyl)diacetic Acid  0   *Acetic Acids *Pyridines. J Am Chem Soc. 2009 Oct 14;131(40):14508-20
plakinic acid J  0   *Acetic Acids *Peroxides. Angew Chem Int Ed Engl 2009;48(24):4367-71
plakinic acid I  0   *Acetic Acids *Peroxides. Angew Chem Int Ed Engl 2009;48(24):4367-71
2,2'-(2,3-bis-phenylsulfanylnaphthalene-1,4-yloxy)diacetic acid  0   *Acetic Acids *Sulfides Ligands. Dalton Trans 2009 Apr 7;(13):2352-8
(4-(4-(5-trifluoromethyl-1H-pyrazol-3-yl)phenyl)cyclohexyl)acetic acid  0   *Acetic Acids *Pyrazoles. Biochem Pharmacol 2009 Apr 15;77(8):1383-90
(4-(4-chloro-3-fluorophenyl)-2-(4-methoxyphenyl)-1,3-thiazol-5-yl)acetic acid  0   *Acetic Acids *Thiazoles. J Pharm Sci 2008 Nov;97(11):4756-82
2-((2S,6S)-6-methyltetrahydro-2H-pyran-2-yl) acetic acid  0   *Acetic Acids *Pyrans. Chem Commun (Camb). 2008 Nov 21;(43):5559-61
mycangimycin  0   *Peroxides *Acetic Acids. Science 2008 Oct 3;322(5898):63
(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetic acid  0   *Acetic Acids *Pyrazines Receptors, Epoprostenol/agonists. J Pharmacol Exp Ther 2008 Sep;326(3):691-9
communiol C  0   *Acetic Acids *Furans. Biosci Biotechnol Biochem 2008 Jul;72(7):1921-8
3,4-dihydroxyphenyl ((2,6-dimethoxy-3-ethylidene)tetrahydropyran-4-yl)acetate  0   *Acetic Acids *Pyrans. J Agric Food Chem 2008 Jul 23;56(14):5582-8
2-(1-hydroxy-2-oxocyclohexyl)acetic acid  0   *Acetic Acids *Cyclohexanones. J Org Chem 2008 May 16;73(10):3938-41
2-(3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)acetic acid  0   *Acetic Acids *Oxadiazoles Aldehyde Reductase/antagonists & inhibitors. J Med Chem 2008 Jun 12;51(11):3182-93
citrantifidiene  0   *Acetic Acids. J Agric Food Chem 2008 May 28;56(10):3569-73
cocoamphodiacetic acid  0   *Acetic Acids Glycine/*analogs & derivatives. J Environ Sci Health A Tox Hazard Subst Environ Eng 2001 Sep;36(8):1451-71
2-(4-((1E)-2-(3,5-dihydroxyphenyl)ethenyl)phenoxy)acetic acid  0   *Acetic Acids *Phenols. Bioorg Med Chem. 2008 Jun 15;16(12):6406-14
4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-ylbut-2-enyloxy)acetic acid  0   *Acetic Acids *Piperazines Receptors, Histamine H1. Drugs R D 2008;9(2):93-112
(2,6-pyridinediylbis(methylene nitrilo)) tetraacetic acid  0   *Acetic Acids *Nitriles *Pyridines. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6230-3
2-((2-hydroxy-5-methyl-3-((pyridin-2-ylmethylamino)methyl)benzyl)(2-hydroxybenzyl)amino)acetic acid  0   *Acetic Acids *Pyridines Ligands. Dalton Trans. 2007 Nov 28;(44):5132-9
5,6-dimethoxy-2,3-dihydro-1H-inden(-1-yl)acetic acid  0   *Acetic Acids *Indenes. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6790-6
alpha-cyano-alpha-fluorophenylacetic acid methyl ester  0   *Acetic Acids *Hydrocarbons, Fluorinated. J Org Chem. 2007 Oct 12;72(21):7923-9
N,N'-di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid  0   *Acetic Acids *Ethylenediamines. Spectrochim Acta A Mol Biomol Spectrosc 2007 Sep;68(1):165-8
DAS734  0   *Acetic Acids *Triazoles. Plant Physiol 2007 Jul;144(3):1292-304
2-(2-fluoro-4-hydroxymethyl-5-methoxy-phenoxy)acetic acid  0   *Acetic Acids *Hydrocarbons, Fluorinated. Org Biomol Chem 2007 Aug 7;5(15):2464-71
p-dimethylaminophenyl-2-chloroethoxyphosphorylacetic acid N-acethylhydrazide  0   *Acetic Acids *Hydrazines *Phosphoric Acids. Eksp Klin Farmakol. 2007 Mar-Apr;70(2):30-2
2-(4-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxyphenyl)-cyclopropyl)acetic acid  0   *Acetic Acids *Naphthyridines. Bioorg Med Chem. 2007 May 15;15(10):3390-412
3,6,9,15-tetraazabicyclo(9.3.1)pentadeca-1(15),11,13-triene-3,6,9-triacetic acid  0   *Acetic Acids *Bicyclo Compounds, Heterocyclic. Inorg Chem 2006 Nov 13;45(23):9269-80
(2-benzyl-2,3,4,5-tetrahydro-1H-pyrido(4,3-b)indole-8-yl)-acetic acid  0   *Acetic Acids *Indoles Aldehyde Reductase/antagonists & inhibitors. Gen Physiol Biophys. 2006 Dec;25(4):415-25
p-bromophenoxyacetic acid  0   *Acetic Acids. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Mar;66(3):773-80
(S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid  0   *Acetic Acids *Oxazoles. J Pharmacol Exp Ther. 2007 Mar;320(3):1038-49
3-(carboxymethoxy)benzoic acid  0   *Acetic Acids *Benzoic Acids. J Med Chem 2006 Dec 14;49(25):7413-26
3-thiophene acetic acid  0   *Acetic Acids *Thiophenes. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys 2006 Dec 21;110(50):25191-202
S-(2-(4-chlorophenyl)-1-phenylethyl)thioglycolic acid  0   *Acetic Acids. EMBO J 2006 Nov 29;25(23):5469-80
4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxyacetic acid  0   *Acetic Acids *Pyrazoles. J Med Chem 2006 Nov 16;49(23):6638-41
(2-naphthoxy)acetyl chloride  0   *Acetic Acids *Naphthalenes. Electrophoresis 2006 Jun;27(12):2300-9
(6,9,15-triscarboxymethyl-3,6,9,15-tetraazabicyclo(9.3.1)pentadec-3-yl)acetic acid  0   *Acetic Acids *Bicyclo Compounds, Heterocyclic Ligands. Nucl Med Biol 2006 May;33(4):459-67
prolyl-4-piperidinylacetic acid  0   *Acetic Acids *Piperidines Proline/*analogs & derivatives. Bioorg Med Chem. 2006 Apr 15;14(8):2725-46
prolyl-1-piperazinylacetic acid  0   *Acetic Acids *Piperazines Proline/*analogs & derivatives. Bioorg Med Chem. 2006 Apr 15;14(8):2725-46
(2S,6S)-(6-methyltetrahydropyran-2-yl)acetic acid  0   *Acetic Acids *Pyrans. Biosci Biotechnol Biochem. 2006 Mar;70(3):712-7
diiodothyroacetic acid  0   *Acetic Acids *Diiodothyronines. Thyroid. 2006 Mar;16(3):273-80
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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