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Acromegaly

More information in Books or onNLM PubMed
Definition: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)  coordinate with GROWTH HORMONE/secret in animals or HUMAN GROWTH HORMONE/secret in humans if pertinent    Other names Somatotropin Hypersecretion Syndrome (Acromegaly); Inappropriate Growth Hormone Secretion Syndrome (A; Syndromes, Somatotropin Hypersecretion (Acromegaly; Syndrome, Somatotropin Hypersecretion (Acromegaly); Somatotropin Hypersecretion Syndromes (Acromegaly); Hypersecretion Syndromes, Somatotropin (Acromegaly; Hypersecretion Syndrome, Somatotropin (Acromegaly); Inappropriate GH Secretion Syndrome (Acromegaly)
 
SubstanceCAS Registry & nameCategoriesSource
Acromelic frontonasal dysplasia  0   *Acromegaly.
Acromegaloid features, overgrowth, cleft palate, and hernia  0   *Abnormalities, Multiple *Acromegaly *Cleft Palate *Growth Disorders *Hernia.
Acromegaloid facial appearance syndrome  0   *Acromegaly *Hypertrichosis *Limb Deformities, Congenital.
Rosenthal-Kloepfer syndrome  0   *Acromegaly *Corneal Opacity *Scalp Dermatoses.
Growth hormone excess  0   *Acromegaly.
pegvisomant  0   Human Growth Hormone/*analogs & derivatives Acromegaly Receptors, Somatotropin/antagonists & inhibitors. N Engl J Med 2000 Apr 20;342(16):1171-7SOMAVERT
lanreotide  118992-92-0 L-Threoninamide, 3-(1-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-, cyclic (2-7)-disulfide  *Peptides, Cyclic Somatostatin/*analogs & derivatives Acromegaly.
Pharma Action Antineoplastic Agents 		Prostaglandins 1989;37(3):345SOMATULINE DEPOT

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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