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Actins

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Definition: Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.      Other names G-Actin; F-Actin; gamma Actin; beta Actin; alpha Isoactin; alpha Actin; N Actin; G Actin; F Actin; gamma-Actin; beta-Actin; alpha-Isoactin; alpha-Actin; N-Actin; Isoactin; Actin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Acta2 protein, mouse  0   *Actins. Am J Physiol Heart Circ Physiol 2011 Mar;300(3):H736-44
alpha-smooth muscle actin, mouse  0   *Actins. Hepatobiliary Pancreat Dis Int 2009 Jun;8(3):300-8
ACTA2 protein, human  0   *Actins. Am J Hum Genet 2009 May;84(5):617-27
Arpm1 protein, mouse  0   *Actins. FEBS Lett 2008 Sep 3;582(20):2998-3004
ACTC1 protein, human  0   *Actins. Hum Mol Genet 2008 Jan 15;17(2):256-65
Act-2 protein, C elegans  0   *Actins *Caenorhabditis elegans Proteins. Mol Biol Cell 2006 Mar;17(3):1051-64
ACT-5 protein, C elegans  0   *Actins *Caenorhabditis elegans Proteins. Mol Biol Cell 2005 Jul;16(7):3247-59
Arp6 protein, S pombe  0   *Actins *Schizosaccharomyces pombe Proteins.
Arp6 protein, Gallus gallus  0   *Actins *Chromosomal Proteins, Non-Histone *Avian Proteins.
Arp6 protein Drosophila  0   *Actins *Chromosomal Proteins, Non-Histone *Drosophila Proteins.
smooth muscle actin, rat  0   *Actins. Gene 1998 Sep 30;69(2):345-8
actin-related protein 1, rat  0   *Actins.
C79802 protein, mouse  0   *Actins *Chromosomal Proteins, Non-Histone *DNA-Binding Proteins.
FGD4 protein, human  0   *Microfilament Proteins Actins. http://www.signaling-gateway.org/molecule/query?afcsid=A000954
Actl7a protein, mouse  0   *Actins. Biol Reprod 2003 Aug;69(2):475-82
ACT7 protein, Arabidopsis  0   *Actins *Arabidopsis Proteins. Plant J 2003 Jan;33(2):319-28
ATARP7 protein, Arabidopsis  0   *Actins *Arabidopsis Proteins Nuclear Proteins. Plant J 2003 Mar;33(5):939-48939-48
ATARP4 protein, Arabidopsis  0   *Actins *Arabidopsis Proteins Nuclear Proteins. Plant J 2003 Mar;33(5):939-48
ParM protein, E coli  0   *Actins *Escherichia coli Proteins. EMBO J 2002 Dec 16;21(24):6935-43
ACTL6B protein, human  0   *Actins *Chromosomal Proteins, Non-Histone *DNA-Binding Proteins. Genes Dev 2002 Oct 1;16(19):2509-17
Act1 protein, S cerevisiae  0   *Actins *Saccharomyces cerevisiae Proteins. EMBO J 2002 Aug 1;21(15):4125-35
ARPM2 protein, human  0   *Actins. Biochim Biophys Acta 2001 Dec 3;1522(2):130-3
ARPM1 protein, human  0   *Actins. Biochim Biophys Acta 2001 Dec 3;1522(2):130-3
CyIIa protein, Strongylocentrotus purpuratus  0   *Actins. J Mol Evol 1987;25(1):37-45
ACTII protein, Echinococcus granulosus  0   *Actins *Helminth Proteins. Braz J Med Biol Res 2000 Nov;33(11):1283-92
ACTI protein, Echinococcus granulosus  0   *Actins *Helminth Proteins. Braz J Med Biol Res 2000 Nov;33(11):1283-92
ACTR6 protein, human  0   *Actins *Chromosomal Proteins, Non-Histone. Gene 2001 May 2;268(1-2):133-40
ACT1 protein, Candida albicans  0   *Actins *Fungal Proteins. J Invest Dermatol 2000 Jan;114(1):95-100
GiaI protein, Crassostrea gigas  0   *Actins. FEBS Lett 1999 Oct 22;460(1):81-5
ACTL7B protein, human  0   *Actins. Genomics 1999 Jun 15;58(3):302-9
ACTL7A protein, human  0   *Actins. Genomics 1999 Jun 15;58(3):302-9
actin-like protein, NAP  0   *Actins. Cell Struct Funct 1998 Oct;23(5):273-81
ACTL6A protein, human  0   *Actins *Chromosomal Proteins, Non-Histone *DNA-Binding Proteins. Cell 1998 Nov 25;95(5):625-36; Genes Dev 2002 Oct 1;16(19):2509-17; Mol Cells 2001 Feb 28;11(1):75-81
ARP7 protein, S cerevisiae  0   *Chromosomal Proteins, Non-Histone *Transcription Factors Actins. Mol Cell 1998 Nov;2(5):639-51
ACT2 protein, Chlamydomonas reinhardtii  0   *Actins *Protozoan Proteins. Gene 1997 Sep 15;197(1-2):153-9
aplyronine A  151923-84-1   *Macrolides Actins/antagonists & inhibitors. J Biochem (Tokyo) 1996 Sep;120(3):552-5
AAC1 protein, Arabidopsis  0   *Actins *Arabidopsis Proteins. Plant Cell 1996 Jan;8(1):15-30
FLII protein, human  0   *Microfilament Proteins *Receptors, Cytoplasmic and Nuclear Actins. Am J Hum Genet 1995 Jan;56(1):175-82; Mol Cell Biol. 2004 Mar;24(5):2103-7
Arp1 protein, Pneumocystis  0   *Actins *Fungal Proteins. J Eukaryot Microbiol 1995 Mar-Apr;42(2):142-9
actin-like protein, chicken  0   *Actins *Avian Proteins. Gene 1995 Mar 10;154(2):205-9
ACLA protein, Dictyostelium discoideum  0   *Actins. FEBS Lett 1995 Mar 6;360(3):235-41
RO-4 protein, Neurospora crassa  0   *Fungal Proteins Actins. J Cell Biol 1994 Oct;127(1):139-49
Arp53D protein, Drosophila  0   *Actins *Drosophila Proteins. J Mol Biol 1994 Aug 19;241(3):498-503
Arp14D protein, Drosophila  0   *Actins *Drosophila Proteins Insect Hormones. J Mol Biol 1994 Aug 19;241(3):498-503
Arp87C protein, Drosophila  0   *Actins *Drosophila Proteins. J Mol Biol 1994 Aug 19;241(3):498-503
Arp4 protein, S cerevisiae  0   *Actins *Nuclear Proteins *Saccharomyces cerevisiae Proteins. Proc Natl Acad Sci U S A 1994 Aug 16;91(17):8258-62
Arp66B protein, Drosophila  0   *Actins *Drosophila Proteins Drosophila melanogaster. Biochem Genet 1993 Aug;31(7-8):329-41
scruin protein, Horseshoe Crab  0   *Actins Horseshoe Crabs. J Cell Biol 1993 Oct;123(2):337-44
actin, (TMB)Cys(374)  0   *Actins *Bicyclo Compounds. FEBS Lett 1993 Aug 23;329(1-2):9-12
ACT2 protein, Arabidopsis  148710-82-1   *Actins *Arabidopsis Proteins. Biochem Biophys Res Commun 1992 Sep 16;187(2):1022-8
centractin  148996-73-0   *Actins. Nature 1992 Sep 17;359(6392):246-50
flight muscle protein, Act88F  149954-56-3   *Actins. Gene 1992 Sep 10;118(2):163-70
coronin proteins  145420-64-0   *Microfilament Proteins Actins Phagosomes Saccharomyces cerevisiae Proteins Drosophila Proteins. EMBO J 1991;10(13):4097
maleimidobenzoyl-G-actin  0   *Actins. Biochemistry 1990;29(38):9085
actobindin  0   *Carrier Proteins Actins Protozoan Proteins. J Biol Chem 1986;261(36):17150
actophorin protein, Acanthamoeba  0   *Microfilament Proteins *Protozoan Proteins Actins. J Biol Chem 1986;261(1):477
arthrin  0   *Actins *Insect Proteins *Ubiquitin. J Mol Biol 1985;182(3):443
su-45 protein, Hemicentrotus pulcherrimus  0   *Cytoskeletal Proteins *Peptide Hydrolases Actins Sea Urchins. J Cell Biol 1984;99(3):994
ADP-G-actin  0   *Actins Adenosine Diphosphate/*analogs & derivatives. J Cell Biol 1984;99(3):769
Cap 42 (a&b) protein, Physarum polycephalum  0   *Cytoskeletal Proteins *Protozoan Proteins Actins Calcium. J Biol Chem 1983;258(16):10144
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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