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Acyltransferases

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Definition: Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (From Enzyme Nomenclature 1992) EC 2.3.     
Examples Acetyl-CoA C-Acyltransferase; Acetyltransferases; Acyl-Carrier Protein S-Malonyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; 1-Acylglycerophosphocholine O-Acyltransferase; Aminoacyltransferases; 5-Aminolevulinate Synthetase; Arylalkylamine N-Acetyltransferase; Arylamine N-Acetyltransferase; ATP Citrate (pro-S)-Lyase; Carnitine Acyltransferases; Citrate (si)-Synthase; Diacylglycerol O-Acyltransferase; Glycerol-3-Phosphate O-Acyltransferase; Homoserine O-Succinyltransferase; Hydroxymethylglutaryl-CoA Synthase; 2-Isopropylmalate Synthase; Malate Synthase; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Phosphatidylcholine-Sterol O-Acyltransferase; Retinol O-Fatty-Acyltransferase; Serine C-Palmitoyltransferase; Sphingosine N-Acyltransferase; Sterol O-Acyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ZDHHC21 protein, human  EC 2.3.-   *Acyltransferases. Mol Biol Cell. 2012 Jan;23(1):188-99.
HIP14 protein, mouse  EC 3.2.1.-   *Acyltransferases Nerve Tissue Proteins. Hum Mol Genet. 2002 Nov 1;11(23):2815-28.
At5g47980 protein, Arabidopsis  EC 2.3.-   *Acyltransferases *Arabidopsis Proteins. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16116-21.
DHHC15 protein, mouse  EC 2.3.-   *Acyltransferases. J Biol Chem 2008 Sep 5;283(36):25014-26
alcohol acyltransferase, Actinidia  EC 2.3.1.-   *Acyltransferases *Plant Proteins. Phytochemistry. 2011 Jun;72(8):700-10
PIG-W protein, mouse  EC 2.3.-   *Acyltransferases. J Biol Chem 2011 Apr 22;286(16):14649-58
ZDHHC14 protein, human  EC 2.3.1.-   *Acyltransferases. Leukemia. 2011 Feb;25(2):367-71
Cst26 protein, S cerevisiae  EC 2.3.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. PLoS One 2010;5(8):e11956
Zdhhc13 protein, mouse  EC 2.3.1.-   *Acyltransferases Zinc Fingers. PLoS Genet 2010;6(6):e1000985
3-hdyroxybutanoyltransferase, E coli  EC 2.3.-   *Acyltransferases *Escherichia coli Proteins. Glycobiology 2010 Jun;20(6):679-88
Ipgat1 protein, mouse  EC 2.3.1.-   *Acyltransferases. J Lipid Res 2010 Jun;51(6):1424-31
DHHC20 protein, human  EC 2.3.-   *Acyltransferases. Mol Membr Biol 2010 Apr;27(2-3):123-36
DHHC19 protein, human  EC 2.3.-   *Acyltransferases. Biochim Biophys Acta. 2010 Mar;1798(3):592-604
Zdhhc21 protein, mouse  EC 2.3.1.-   *Acyltransferases Zinc Fingers. PLoS Genet 2009 Nov;5(11):e1000748
3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase, Taxus canadensis  EC 2.3.-   *Acyltransferases. J Nat Prod. 2010 Feb 26;73(2):151-9
DCR protein, Arabidopsis  EC 2.3.-   *Acyltransferases *Arabidopsis Proteins. Plant Physiol 2009 Dec;151(4):1773-89
RWP1 protein, Arabidopsis  EC 2.3.-   *Acyltransferases *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2009 Nov 3;106(44):18855-60
ghrelin O-acyltransferase, human  EC 2.3.-   *Acyltransferases. Arthritis Rheum. 2009 Jun;60(6); 1704-9
ZDHHC8 protein, mouse  EC 2.3.1.-   *Acyltransferases *Membrane Proteins Zinc Fingers. Mol Cell Neurosci. 2008 Nov;39(3):439-51
Bus-1 protein, C elegans  EC 2.3.-   *Acyltransferases *Caenorhabditis elegans Proteins. Dev Dyn 2008 Dec;237(12):3762-76
ghrelin O-acyltransferase, rat  EC 3.1.-   *Acyltransferases. J Mol Endocrinol 2008 Dec;41(6):415-21
ZDHHC2 protein, human  EC 2.3.-   *Acyltransferases *Tumor Suppressor Proteins Zinc Fingers. Mol Cell Proteomics 2008 Jul;7(7):1378-88
Rv1347c, Mycobacterium tuberculosis  EC 2.3.1.-   *Acyltransferases. Arch Biochem Biophys 2008 Sep 15;477(2):259-66
glycerophosphocholine acyltransferase, S cerevisiae  EC 2.3.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. J Lipid Res 2008 Aug;49(8):1794-806
YdcS protein, E coli  EC 2.3.1.-   *Acyltransferases *Escherichia coli Proteins ATP-Binding Cassette Transporters. Biochem Biophys Res Commun 2008 Sep 26;374(3):485-9
malonyl-coenzyme A-21-hydroxypregnane 21-O-malonyltransferase  EC 2.3.1.-   *Acyltransferases. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Dec 15;860(2):195-201
N-myristoyltransferase, mouse  EC 2.3.1.97   *Acyltransferases. J Biol Chem 1998 Mar 20;273(12):6595-8
ghrelin O-acyltransferase, mouse  EC 2.3.-   *Acyltransferases. Cell 2008 Feb 8;132(3):387-96
Mu Mom protein, bacteriophage Mu  EC 2.3.-   *Acyltransferases *Viral Proteins. Cell Cycle 2008 Jan;7(1):120-1
HIP14 protein, Drosophila  EC 2.3.1.-   *Acyltransferases *Drosophila Proteins. J Cell Biol 2007 Dec 31;179(7):1481-96
lysocardiolipin acyltransferase, mouse  EC 2.3.1.-   *Acyltransferases. Blood 2007 Nov 15;110(10):3601-9
acyl-coenzyme A testosterone acyltransferase, Ilyanassa obsoleta  EC 2.3.-   *Acyltransferases. Gen Comp Endocrinol 2001 May;122(1):172-80
sinapoyl-Glc-sinapoyl-Glc sinapoyltransferase, Arabidopsis  EC 2.3.1.-   *Acyltransferases *Arabidopsis Proteins. Plant Physiol 2007 Aug;144(4):1986-99
sinapoyl-Glc-anthocyanin sinapoyltransferase, Arabidopsis  EC 2.3.1.-   *Acyltransferases *Arabidopsis Proteins. Plant Physiol 2007 Aug;144(4):1986-99
hydroxycinnamoyl-CoA shikimate hydroxycinnamoyltransferase, Pinus radiata  EC 2.3.-   *Acyltransferases. Proc Natl Acad Sci U S A 2007 Jul 10;104(28):11856-61
HCT protein, Arabidopsis  EC 2.3.1.-   *Acyltransferases *Arabidopsis Proteins. Plant Cell 2007 Jan;19(1):148-62
RLP-1 protein, rat  EC 2.3.1.-   *Acyltransferases. J Biol Chem 2007 Feb 9;282(6):3614-23
NMT2 protein, rat  EC 2.3.1.-   *Acyltransferases. Mol Cell Biochem. 2006 Jun;286(1-2):161-70
NMT1 protein, rat  EC 2.3.1.-   *Acyltransferases. Mol Cell Biochem. 2006 Jun;286(1-2):161-70
Pfa4 protein, S cerevisiae  EC 2.3.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. Cell 2006 Jun 2;125(5):1003-13
LPAT2 protein, Arabidopsis  EC 2.3.1.52   *Acyltransferases *Arabidopsis Proteins. Plant Cell 2005 Apr;17(4):1073-89
TIP1 protein, Arabidopsis  EC 2.3.1.-   *Acyltransferases *Arabidopsis Proteins. Plant Cell 2005 Sep;17(9):2554-63
Pfa3 protein, S cerevisiae  EC 2.3.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. J Cell Biol 2005 Sep 26;170(7):1091-9
ZDHHC9 protein, human  EC 2.3.1.-   *Acyltransferases Zinc Fingers. J Biol Chem 2005 Sep 2;280(35):31141-8
Swf1 protein, S cerevisiae  EC 2.3.1.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. EMBO J 2005 Jul 20;24(14):2524-32
AWAT2 protein, human  EC 2.3.1.-   *Acyltransferases. J Biol Chem 2005 Apr 15;280(15):14755-64
AWAT1 protein, human  EC 2.3.1.75   *Acyltransferases. J Biol Chem 2005 Apr 15;280(15):14755-64
LPGAT1 protein, human  EC 2.3.-   *Acyltransferases. J Biol Chem 2004 Dec 31;279(53):55866-74
wax synthase, human  EC 2.3.-   *Acyltransferases. J Biol Chem 2004 Sep 3;279(36):37798-807
wax synthase, mouse  EC 2.3.-   *Acyltransferases. J Biol Chem 2004 Sep 3;279(36):37798-807
HtrB protein, E coli  EC 2.3.-   *Acyltransferases *Escherichia coli Proteins.
hydroxycinnamoyl-coenzyme A-tyramine N-(hydroxycinnamoyl)transferase, Capsicum annuum  EC 2.3.1.-   *Plant Proteins *Acyltransferases. Plant Physiol 2004 May;135(1):346-56
CHS protein, Arabidopsis  EC 2.3.1.74   *Acyltransferases *Arabidopsis Proteins Chalcones.
ZDHHC8 protein, human  EC 2.3.1.-   *Acyltransferases *Membrane Proteins Zinc Fingers. Nat Genet 2004 Jul;36(7):725-31
PapA5 protein, Mycobacterium tuberculosis  EC 2.3.-   *Acyltransferases. Proc Natl Acad Sci U S A 2004 Mar 30;101(13):4608-13
ZDHHC16 protein, human  EC 2.3.1.-   *Acyltransferases.
ZDHHC1 protein, human  EC 2.3.1.-   *Acyltransferases.
Taz1 protein, S cerevisiae  EC 2.3.-   *Acyltransferases *Saccharomyces cerevisiae Proteins. Mol Microbiol 2004 Jan;51(1):149-58
malonyl-coenzyme A anthocyanidin 3-O-glucoside-6''-O-malonyltransferase  EC 2.3.1.-   *Acyltransferases. Plant Physiol 2002 Dec;130(4):2142-51
agmatine coumaroyltransferase  EC 2.3.1.64   *Acyltransferases. J Biol Chem 2003 Apr 18;278(16):13919-27
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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