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Adamantane

More information in Books or onNLM PubMed
Definition: A tricyclo bridged hydrocarbon.  a cycloparaffin   
Examples Amantadine; Methenamine; Rimantadine 		Other names Diamantane
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
adamantyl-N-acetylcystein  0   Acetylcysteine/*analogs & derivatives Adamantane/*analogs & derivatives. Chem Biol Drug Des. 2012 Jan;79(1):92-103
adamantyl isothiocyanate  0   *Isothiocyanates Adamantane/*analogs & derivatives. Chem Biol Drug Des. 2012 Jan;79(1):92-103
methyl 2-(cyclohexanecarboxamido)-4-ethyl-5-methylthiophene-3-carboxylate  0   *Thiophenes Adamantane/*analogs & derivatives GABA-B Receptor Agonists. J Pharmacol Exp Ther. 2012 Mar;340(3):529-38.
methyl 2-(1-adamantanecarboxamido)-4-ethyl-5-methylthiophene-3-carboxylate  0   *Thiophenes Adamantane/*analogs & derivatives GABA-B Receptor Agonists. J Pharmacol Exp Ther. 2012 Mar;340(3):529-38.
NSC305787  0   *Quinolines Adamantane/*analogs & derivatives. Oncogene. 2012 Jan 19;31(3):269-81.
1-((2-adamantyl)amino)acetyl-2-cyano-(S)-pyrrolidine, monohydrochloride  0   *Nitriles *Pyrrolidines Adamantane/*analogs & derivatives Hypoglycemic Agents Dipeptidyl-Peptidase IV Inhibitors. J Pharmacol Exp Ther. 2012 Jan;340(1):64-72
3-(4-chlorophenyl)adamantane-1-carboxylic acid 3,4-dihydroxybenzylamide  0   *Catechols Adamantane/*analogs & derivatives. Invest New Drugs. 2011 Dec;29(6):1132-42.
2-quinoxaline-carboxamide-N-adamantan-1-yl  0   *Quinoxalines Adamantane/*analogs & derivatives Receptors, Calcium-Sensing/antagonists & inhibitors. Mol Pharmacol. 2003 May;63(5):1082-93.
SQ 609  0   *Piperidines Adamantane/*analogs & derivatives. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5353-7.
N-(adamantan-1-yl)-8-methoxy-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide  0   *Quinolones Adamantane/*analogs & derivatives Ligands Receptor, Cannabinoid, CB2. J Med Chem 2011 Aug 11;54(15):5444-53
2-((1-adamantyl(methyl)amino)methyl)-1-phenylcyclopropanecarboxylic acid  0   *Cyclopropanes Adamantane/*analogs & derivatives Receptors, sigma/agonists. J Alzheimers Dis 2011;24(3):569-86
5-hydroxysaxagliptin  0   *Dipeptides Adamantane/*analogs & derivatives. Clin Pharmacokinet. 2011 Apr 1;50(4):253-65
OZ 439  0   *Peroxides Adamantane/*analogs & derivatives. Proc Natl Acad Sci U S A 2011 Mar 15;108(11):4400-5
N-hydroxy-6-(((adamantan-1-ylamino)carbonyl)amino)hexamide  0   *Hydroxamic Acids Adamantane/*analogs & derivatives Histone Deacetylase Inhibitors. Int J Radiat Oncol Biol Phys 2011 Apr 1;79(5):1541-8
1-(1-acetyl-piperidine-4-yl)-3-adamantan-1-yl-urea  0   Adamantane/*analogs & derivatives Urea/*analogs & derivatives Epoxide Hydrolases/antagonists & inhibitors. Eur J Pharmacol 2011 Mar 1;654(1):68-74
2-(1-adamantyl)ethyl 4-((2,5-dihydroxyphenyl)methylamino)benzoate  0   *Benzoates Adamantane/*analogs & derivatives. Bioorg Med Chem Lett. 2011 Jan 1;21(1):577-83
3-(2-(3-(1-adamantyl)-4-hydroxyphenyl)-5-pyrimidinyl)-2-propenoic acid  0   *Acrylates Adamantane/*analogs & derivatives. Mol Cancer Ther 2010 Nov;9(11):2903-13
2,2-bis(4-pyridoindolyl-9-lyphenyl)adamantane  0   *Indoles Adamantane/*analogs & derivatives. Adv Mater. 2010 Nov 9;22(42):4775-8
hyperibone K  0   *Hemiterpenes Adamantane/*analogs & derivatives. J Org Chem 2007 Sep 14;72(19):7386-9
1,3,5,7-tetramethyl-6-phenyl-2,4,8-trioxa-6-phospha-adamantane  0   Adamantane/*analogs & derivatives. J Org Chem. 2010 Sep 17;75(18):6297-9
lipoyl vildagliptin  0   Adamantane/*analogs & derivatives Thioctic Acid/*analogs & derivatives Dipeptidyl Peptidase 4. Xenobiotica 2010 Oct;40(10):707-12
1-adamantanethiol  0   *Sulfhydryl Compounds Adamantane/*analogs & derivatives. ACS Nano 2010 Jul 27;4(7):3949-58
4-(2-adamantan-1-yl-2-oxoethoxymethyl)-N,N-dimethylbenzamide  0   *Benzamides Adamantane/*analogs & derivatives 11-beta-Hydroxysteroid Dehydrogenase Type 1/antagonists & inhibitors. ChemMedChem 2010 Jul 5;5(7):1026-44
PF 877423  0   *Pyrrolidines Adamantane/*analogs & derivatives 11-beta-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Bioorg Med Chem Lett 2010 May 1;20(9):2897-902
1,3-adamantanediol  0   Adamantane/*analogs & derivatives. J Biosci Bioeng. 2010 Jun;109(6):550-3
platencin A3  0   *Aminobenzoic Acids Adamantane/*analogs & derivatives. Bioorg Med Chem. 2010 Apr 1;18(7):2602-10
platencin A4  0   *Aminobenzoic Acids Adamantane/*analogs & derivatives. Bioorg Med Chem. 2010 Apr 1;18(7):2602-10
platencin A2  0   *Aminobenzoic Acids Adamantane/*analogs & derivatives. Bioorg Med Chem. 2010 Apr 1;18(7):2602-10
3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide  0   *Pyridines Adamantane/*analogs & derivatives. J Pharmacol Exp Ther 2010 Apr;333(1):129-39
aziadamantane  0   Adamantane/*analogs & derivatives. Org Lett. 2010 Jan 15;12(2):332-5
N-(2-methyl-5-(9-oxa-3,7-diazabicyclo(3.3.1)non-3-ylcarbonyl)phenyl)-2-tricyclo(3.3.1.13,7)dec-1-ylacetamide  0   *Azabicyclo Compounds Adamantane/*analogs & derivatives. J Med Chem. 2007 Nov 29;50(24):5882-5
TIPP 703  0   *Phenylpropionates Adamantane/*analogs & derivatives Peroxisome Proliferator-Activated Receptors/agonists. Acta Crystallogr D Biol Crystallogr 2009 Aug;65(Pt 8):786-95
1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane  0   Adamantane/*analogs & derivatives. Org Lett. 2009 Aug 6;11(15):3210-3
platencin A1  0   *Aminobenzoic Acids Adamantane/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4756-9
isoplatensimycin  0   *Aminobenzoic Acids *Anilides Adamantane/*analogs & derivatives. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4601-2
2-(1-adamantylethynyl)pyrimidine-5-carbaldehyde  0   *Aldehydes Adamantane/*analogs & derivatives. Chemistry. 2009 Aug 17;15(33):8251-8
AC1 004  0   *Benzimidazoles Adamantane/*analogs & derivatives. Biochem Biophys Res Commun 2009 Jul 17;385(1):16-21
7-nitro-1,3,5-triazaadamantane  0   *Aza Compounds Adamantane/*analogs & derivatives. J Phys Chem B 2009 Apr 9;113(14):4775-80
caloundrin B  0   Adamantane/*analogs & derivatives. Org Lett 2009 Mar 19;11(6):1373-6
(1R,3R,5R,7R,8S,9R,10S)-3,5-diethyl-8,9,10-trimethyl-2,4,6-trioxatricyclo(3.3.1.13,7)decan-1-ol  0   Adamantane/*analogs & derivatives. Org Lett 2009 Mar 19;11(6):1373-6
1-cyanoadamantane  0   *Nitriles Adamantane/*analogs & derivatives. J Chem Phys 2008 Sep 7;129(9):094501
N-(adamantan-1-ylmethyl)-5-((3-aminopyrrolidin-1-yl)methyl)-2-chlorobenzamide  0   *Benzamides Adamantane/*analogs & derivatives Receptors, Purinergic P2/antagonists & inhibitors. GSK 314181A620-33
N-(1-adamantyl)phthalimide  0   *Phthalimides Adamantane/*analogs & derivatives. Org Lett. 2008 Sep 18;10(18):3965-8
2,4-methanoadamantane-benzazepine  0   *Benzazepines Adamantane/*analogs & derivatives. Org Lett. 2008 Sep 18;10(18):3965-8
1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone  0   *Imidazoles Adamantane/*analogs & derivatives Heme Oxygenase-1/antagonists & inhibitors. J Med Chem 2008 Oct 9;51(19):5943-52
2-(3-noradamantylamino)-1-thia-3-azaspiro(4.4)non-2-en-4-one  0   *Thiazoles Adamantane/*analogs & derivatives 11-beta-Hydroxysteroid Dehydrogenase Type 1/antagonists & inhibitors. J Med Chem 2008 May 22;51(10):2933-43
OZ381  0   *Peroxides *Spiro Compounds Adamantane/*analogs & derivatives. Bioorg Med Chem Lett 2008 Mar 1;18(5):1555-8
OZ397  0   *Peroxides *Spiro Compounds Adamantane/*analogs & derivatives. Bioorg Med Chem Lett 2008 Mar 1;18(5):1555-8
1-(4-(4-(adamant-1-yl)phenoxymethyl)-2-(4-bromophenyl)-1,3-dioxolan-2-ylmethyl)imidazole  0   *Imidazoles Adamantane/*analogs & derivatives. Acta Pol Pharm 2007 Nov-Dec;64(6):535-41
4-(adamantyl-1)-1-(1-aminobutyl)benzol  0   Adamantane/*analogs & derivatives. Mikrobiol Z 2007 Sep-Oct;69(5):42-8
hemantane  0   Adamantane/*analogs & derivatives. Eksp Klin Farmakol 2007 Jul-Aug;70(4):11-4
2-aza-1-methyladamantane N-oxyl  0   *Cyclic N-Oxides Adamantane/*analogs & derivatives. J Am Chem Soc 2006 Jul 5;128(26):8412-3
2-azaadamantane N-oxyl  0   *Cyclic N-Oxides Adamantane/*analogs & derivatives. J Am Chem Soc 2006 Jul 5;128(26):8412-3
1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl 1-adamantylacetate  0   *Piperidines Adamantane/*analogs & derivatives Free Radicals. Biochemistry (Mosc). 2007 May;72(5):558-64
sinaicinone  0   Adamantane/*analogs & derivatives. Phytochemistry 2007 May;68(9):1272-6
adamantyl naphthalene diimide  0   *Imides Adamantane/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2004;(48):103-4
(25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3  0   Adamantane/*analogs & derivatives Calcitriol/*analogs & derivatives. Arch Biochem Biophys 2007 Apr 15;460(2):240-53
OZ78 compound  0   Adamantane/*analogs & derivatives. J Antimicrob Chemother 2006 Dec;58(6):1193-7
N-(5-hydroxy-2-adamantyl)-2(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propionamide  0   *Piperazines Adamantane/*analogs & derivatives 11-beta-Hydroxysteroid Dehydrogenase Type 1/antagonists & inhibitors. J Med Chem 2007 Jan 11;50(1):149-64
N-(5-hydroxy-2-adamantyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide  0   *Piperazines Adamantane/*analogs & derivatives 11-beta-Hydroxysteroid Dehydrogenase Type 1/antagonists & inhibitors. J Med Chem 2007 Jan 11;50(1):149-64
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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