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Addison Disease

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Definition: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.      Other names Primary Adrenocortical Insufficiencies; Insufficiency, Primary Adrenocortical; Insufficiencies, Primary Adrenocortical; Hypoadrenalisms, Primary; Hypoadrenalism, Primary; Disease, Addison; Adrenocortical Insufficiency, Primary; Adrenocortical Insufficiencies, Primary; Adrenal Insufficiency, Primary; Addisons Disease; Primary Hypoadrenalism; Primary Adrenocortical Insufficiency; Primary Adrenal Insufficiency; Addison's Disease

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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