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Adenosine Triphosphatases

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Definition: A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.     
Examples Arsenite Transporting ATPases; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Chaperonins; DNA Helicases; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Molecular Motor Proteins; MutS DNA Mismatch-Binding Protein; MutS Homolog 2 Protein; N-Ethylmaleimide-Sensitive Proteins; Proton-Translocating ATPases; RecQ Helicases; Sodium-Potassium-Exchanging ATPase 		Other names Adenosinetriphosphatase; ATPases; Triphosphatase, Adenosine; DNA Dependent Adenosinetriphosphatases; DNA Dependent ATPase; Adenosinetriphosphatases, DNA-Dependent; ATPase, DNA Dependent; DNA-Dependent Adenosinetriphosphatases; DNA-Dependent ATPase; Adenosine Triphosphatase; ATPase, DNA-Dependent; ATPase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TAT-5 protein, C elegans  EC 3.6.1.-   *Adenosine Triphosphatases *Caenorhabditis elegans Proteins. Curr Biol. 2011 Dec 6;21(23):1951-9.
ATAD3C protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *Membrane Proteins *Mitochondrial Proteins. Med Sci (Paris). 2011 Dec;27(12):1089-95
katanin-P60 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases. Prostate. 2012 Feb;72(3):291-300
SMC-3 protein, C elegans  EC 3.6.1.3   *Chromosomal Proteins, Non-Histone *Caenorhabditis elegans Proteins Adenosine Triphosphatases Protein Subunits. PLoS One. 2011;6(9):e24799.
CAHL protein, human  EC 3.6.1.-   *Adenosine Triphosphatases. PLoS One 2011;6(4):e18285
BTAF1 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *Transcription Factors. Mech Dev 2011 May-Jun;128(5-6):279-88
ATPase-in-seed-development protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Arabidopsis Proteins Mitochondrial Proteins. Mol Cells 2011 Apr;31(4):361-9
SKD1 protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Arabidopsis Proteins. Plant Signal Behav 2010 Oct;5(10):1308-10
YchF protein, E. coli  EC 3.6.1.-   *Adenosine Triphosphatases *Escherichia coli Proteins. Biochem Biophys Res Commun. 2011 May 13;408(3):459-64
ATAD2B protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *Nuclear Proteins. Dev Growth Differ 2010 Dec;52(9):747-55
Atad1 protein, rat  EC 3.6.1.-   *Adenosine Triphosphatases. Cell 2011 Apr 15;145(2):284-99
spastin protein, zebrafish  EC 3.6.1.-   *Adenosine Triphosphatases *Zebrafish Proteins. Dis Model Mech 2010 Nov-Dec;3(11-12):743-51
katanin-P60 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases. Neuroreport 2010 Jun 23;21(9):646-50
Rad17 protein, Xenopus  EC 3.6.1.-   *Adenosine Triphosphatases *Xenopus Proteins Cell Cycle Proteins. Mol Biol Cell 2010 Mar;21(6):926-35
MORC3 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *DNA-Binding Proteins Zinc Fingers. J Cell Sci 2010 Jun 15;123(Pt 12):2014-24
MORC3 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *DNA-Binding Proteins Zinc Fingers. J Cell Sci 2010 Jun 15;123(Pt 12):2014-24
ATP19 protein, S cerevisiae  EC 3.6.3.14   *Adenosine Triphosphatases *Saccharomyces cerevisiae Proteins Protein Subunits. Mol Biol Cell 2010 May;21(9):1494-504
ATP13A4 protein, mouse  EC 3.6.1.3   *Adenosine Triphosphatases. Cell Mol Neurobiol 2010 Mar;30(2):233-46
Atp7b protein, rat  EC 3.6.3.4   *Adenosine Triphosphatases *Cation Transport Proteins. Bull Exp Biol Med 2009 Oct;148(4):592-7
ATAD3A protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *Membrane Proteins *Mitochondrial Proteins.
DOC45 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases Neoplasm Proteins. Mol Cancer Res 2010 Jan;8(1):57-66
CATP-5 protein, C elegans  EC 3.6.1.-   *Adenosine Triphosphatases *Membrane Proteins *Caenorhabditis elegans Proteins Protein Isoforms. FASEB J. 2010 Jan;24(1):206-17
HMA7 protein, Arabidopsis  EC 3.6.1.3   *Adenosine Triphosphatases *Arabidopsis Proteins. Chem Commun (Camb). 2009 Nov 14;(42):6364-6
HSP104 protein, S pombe  EC 3.6.1.-   *Adenosine Triphosphatases *Heat-Shock Proteins. PLoS One 2009;4(9):e6939
ATAD5 protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *DNA-Binding Proteins. Cell Cycle. 2009 Oct 1;8(19):3199-207
8-methoxycoumestrol  0   Coumestrol/*analogs & derivatives Adenosine Triphosphatases/antagonists & inhibitors. J Cardiovasc Pharmacol 2009 Jul;54(1):10-5
ATP8a2 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *Phospholipid Transfer Proteins. J Biol Chem 2009 Nov 20;284(47):32670-9
ATP8A2 protein, human  EC 3.6.3.1   *Adenosine Triphosphatases *Phospholipid Transfer Proteins. J Biol Chem 2009 Nov 20;284(47):32670-9
PFIC1 protein, rat  EC 3.6.1.3.   *Adenosine Triphosphatases. Hepatology. 2009 Nov;50(5):1597-605
ATAD2 protein, human  EC 3.6.1.3   *Adenosine Triphosphatases *DNA-Binding Proteins. Cancer Res. 2009 Nov 1;69(21):8491-8
At4g30490 protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Arabidopsis Proteins Calmodulin-Binding Proteins. FEBS J 2009 Jul;276(14):3870-80
PDR2 protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Arabidopsis Proteins. Proc Natl Acad Sci U S A 2009 Aug 18;106(33):14174-9
Psmc3 protein, rat  0   *Adenosine Triphosphatases Proteasome Endopeptidase Complex. Dev Dyn 2009 Jul;238(7):1851-61
RPT5b protein, Arabidopsis  EC 3.6.1.3   *Adenosine Triphosphatases *Arabidopsis Proteins. Plant Cell 2009 Feb;21(2):442-59
RPT5a protein, Arabidopsis  EC 3.6.1.3   *Adenosine Triphosphatases *Arabidopsis Proteins. Plant Cell 2009 Feb;21(2):442-59
SMC3 protein, Drosophila  EC 3.6.1.3   *Adenosine Triphosphatases *Drosophila Proteins Chromosomal Proteins, Non-Histone. Chromosome Res 2009;17(2):185-200
RPT5 protein, S cerevisiae  EC 3.6.1.-   *Adenosine Triphosphatases *Saccharomyces cerevisiae Proteins. Cell 2009 May 29;137(5):887-99
katanin p60-like 1 protein, Drosophila  EC 3.6.1.3   *Adenosine Triphosphatases *Drosophila Proteins. Proc Natl Acad Sci U S A 2009 Apr 14;106(15):6363-8
Atp8b1 protein, rat  EC 3.6.3.1   *Adenosine Triphosphatases *Phospholipid Transfer Proteins. Gastroenterology 2009 Mar;136(3):1060-9
Vps4 protein, Drosophila  EC 3.6.1.3   *Adenosine Triphosphatases *Drosophila Proteins *Endosomal Sorting Complexes Required for Transport Tumor Suppressor Proteins. PLoS ONE 2009;4(2):e4354
Atp8b3 protein, mouse  EC 3.6.3.1   *Adenosine Triphosphatases *Phospholipid Transfer Proteins. Reproduction 2009 Feb;137(2):345-51
Snf2SR protein, S pombe  EC 3.6.1.-   *Adenosine Triphosphatases *Schizosaccharomyces pombe Proteins DNA-Binding Proteins. Genes Cells 2008 Jun;13(6):571-82
HrtA protein, Staphylococcus aureus  EC 3.6.1.-   *Adenosine Triphosphatases. J Bacteriol 2008 May;190(10):3588-96
CAP-D3 protein, Drosophila  EC 3.6.1.-   *Adenosine Triphosphatases *Drosophila Proteins DNA-Binding Proteins Protein Subunits. Genes Dev 2008 Apr 15;22(8):1011-24
Get3 protein, S cerevisiae  EC 3.6.3.16   *Adenosine Triphosphatases *Guanine Nucleotide Exchange Factors *Saccharomyces cerevisiae Proteins. Biometals 2003 Sep;16(3):369-78
Brm protein, rat  EC 3.6.1.-   *Adenosine Triphosphatases *Cell Cycle Proteins. J Biol Chem 2007 Nov 30;282(48):35187-201
TGD3 protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Carrier Proteins *Arabidopsis Proteins. J Biol Chem 2007 Dec 7;282(49):35945-53
CDC48A protein, Arabidopsis  EC 3.6.1.-   *Cell Cycle Proteins *Arabidopsis Proteins Adenosine Triphosphatases. Plant Physiol 2007 Oct;145(2):339-50
Lex-1 protein, C elegans  EC 3.6.1.-   *Adenosine Triphosphatases *Caenorhabditis elegans Proteins Transcription Factors. Mol Genet Genomics 2007 Nov;278(5):507-18
MLH1 protein, Arabidopsis  EC 3.6.1.-   *Adenosine Triphosphatases *Arabidopsis Proteins DNA Repair. Mol Gen Genet 1999 Dec;262(4-5):633-42
pachytene checkpoint 2 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *Cell Cycle Proteins Genes, cdc. PLoS Genet 2007 Aug 10;3(8):e130
Afg1 protein, S cerevisiae  EC 3.6.1.-   *Adenosine Triphosphatases *Mitochondrial Proteins *Saccharomyces cerevisiae Proteins. J Biol Chem 2007 Jun 15;282(24):17442-9
OLA1 protein, human  EC 3.6.3.-   *Adenosine Triphosphatases *GTP-Binding Proteins. J Biol Chem 2007 Jul 6;282(27):19928-37
fidgetin-like 1 protein, mouse  EC 3.6.1.-   *Adenosine Triphosphatases *Nuclear Proteins. J Bone Miner Res 2007 Jun;22(6):889-96
ATAD3B protein, human  EC 3.6.1.-   *Adenosine Triphosphatases *Membrane Proteins *Mitochondrial Proteins. J Cell Biol 2007 Jan 15;176(2):141-6
katanin-60 protein, Drosophila  EC 3.6.1.3   *Adenosine Triphosphatases *Drosophila Proteins Protein Subunits. Curr Biol 2005 Apr 12;15(7):650-5
CHD4 protein, Xenopus  EC 3.6.1.-   *Adenosine Triphosphatases *Xenopus Proteins DNA-Binding Proteins. Genes Dev 2007 Apr 15;21(8):973-83
nucleoside triphosphate diphosphohydrolase 8, human  EC 3.6.1.3   *Adenosine Triphosphatases. Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G785-95
nucleoside triphosphate diphosphohydrolase 8, rat  EC 3.6.1.3   *Adenosine Triphosphatases. Am J Physiol Gastrointest Liver Physiol. 2007 Mar;292(3):G785-95
mitofusin-binding protein, rat  0   *Carrier Proteins Adenosine Triphosphatases. J Cell Sci 2006 Dec 1;119(Pt 23):4913-25
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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