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beta-Aminoethyl Isothiourea

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Definition: A radiation-protective agent that can inhibit DNA damage by binding to the DNA. It also increases the susceptibility of blood cells to complement-mediated lysis.     
Pharmacological Action Radiation-Protective Agents 		Other names beta-Aminoethylisothiuronium Dihydrobromide; beta-Aminoethylisothiuronium Diacetate; 2-Aminoethylisothiuronium Bromide; beta Aminoethylisothiuronium Monohydrobromide; beta Aminoethylisothiuronium Diperchlorate; beta Aminoethylisothiuronium Dihydroiodide; beta Aminoethylisothiuronium Dihydrochloride; beta Aminoethylisothiuronium Dihydrobromide; beta Aminoethylisothiuronium Diacetate; beta Aminoethylisothiuronium Bromide; beta Aminoethyl Isothiourea; Monohydrobromide, beta-Aminoethylisothiuronium; Monohydrobromide, 2-Aminoethylisothiuronium; Hydrobromide, Aminoethylisothiuronium Bromide; Diperchlorate, beta-Aminoethylisothiuronium; Diperchlorate, 2-Aminoethylisothiuronium; Dihydroiodide, beta-Aminoethylisothiuronium; Dihydroiodide, 2-Aminoethylisothiuronium; Dihydrochloride, beta-Aminoethylisothiuronium; Dihydrochloride, 2-Aminoethylisothiuronium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bromoethylisothiourea  82154-73-2   beta-Aminoethyl Isothiourea/*analogs & derivatives. Radiobiologiia 1982;22(2):252
Adeturon  63346-83-8 S-2-aminoethyl-isothiuronium adenosine triphosphate  Adenosine Triphosphate/*analogs & derivatives beta-Aminoethyl Isothiourea/*analogs & derivatives.
Pharma Action Radiation-Protective Agents 		Experientia 32(7):924;1976; Radiobiologiia 18(1):46;1978; Radiobiologiia 1980;20(1):51

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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