encyclopedia of medical concepts
ψ 

Affinity Labels

More information in Books or onNLM PubMed
Definition: Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.  D25-26 qualif; use with caution: few apply   
Examples Photoaffinity Labels 		Other names Affinity Labeling Reagents; Reagents, Affinity Labeling; Labels, Affinity; Labeling Reagents, Affinity
Substances having this pharmacologic action: dihydro-DIDS; 8-azidoadenosine diphosphate; adenosine 5'-O-(2-thiotriphosphate); adenosine 5'-O-(3-thiotriphosphate); 3,3'-dioctadecylindocarbocyanine; MSH, 4-Nle-7-Phe-alpha-; dexamethasone 21-methanesulfonate; GTP gamma-4-azidoanilide; ethylene glycolylbis(succinimidyl succinate); hydroxysuccinimidyl-4-azidobenzoate; lysine-sepharose; 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate; heparin-sepharose; 2-azidoadenosine 5'-triphosphate; 4-nitrobenzylthioinosine; azidopine; 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane; glycocyamine; Propylbenzilylcholine Mustard; Thiouridine; NAP taurine; 5'-(4-fluorosulfonylbenzoyl)adenosine; 3'-O-(3-(N-(4-azido-2-nitrophenyl)amino)propionyl)adenosine-5'-triphosphate; 8-azidoethidium; 3,3'-dipropyloxadicarbocyanine; 8-azidoadenosine 5'-triphosphate; 8-azidoadenosine-3',5'-monophosphate; bromopyruvate; 2',3'-dialdehyde ATP; 8-azidoguanosine triphosphate; 2-(2-benzofuranyl)-2-imidazoline; 2-N-(4-(1-azitrifluoroethyl)benzoyl)-1,3-bis-(mannos-4-yloxy)-2-propylamine; 4-iodoclonidine; enkephalin-Leu, Ala(2)-Cys(6)-; pyridoxal 5'-diphospho-5'-adenosine; PK 14105; Ro 15-4513; 3'-O-(N-methylanthraniloyl) ATP; photobiotin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-(4-azidophenoxy)nonanoic acid  0   *Azides *Fatty Acids Affinity Labels. J Biol Chem 2000 Dec 8;275(49):38547-53
biotin-aminohexylamino-glycyl-glycyl-leucyl-epoxysuccinyl-leucyl-proline  0   *Oligopeptides Biotin/*analogs & derivatives Affinity Labels.
rhodamine B-aminohexylamino-glycyl-glycyl-leucyl-epoxysuccinyl-leucyl-proline  0   *Oligopeptides *Rhodamines Affinity Labels. FEBS Lett 2000 Sep 29;482(1-2):91-6

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy