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Ajmaline

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Definition: An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.     
Pharmacological Action Anti-Arrhythmia Agents
Examples Prajmaline 		Other names Lorajmine; Ajmaline Solvay Brand; Ajmaline Servier Brand; Ajmaline Protea Brand; Ajmaline Lacer Brand; Ajmaline Giulini Brand; Ajmaline Forest Brand; Tachmalin; Solvay Brand of Ajmaline; Wolfina; Servier Brand of Ajmaline; Serenol; Rauverid; Protea Brand of Ajmaline; Lacer Brand of Ajmaline; Giulini Brand of Ajmaline; Gilurtymal; Forest Brand of Ajmaline; Cardiorythmine; AritminaDrugs* : WOLFINA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
raumacline  0   Ajmaline/*analogs & derivatives Alkaloids. Chem Commun (Camb). 2003 Nov 21;(22):2800-1
17-O-(3',4',5'-trimethoxybenzoyl)ajmaline  0   *Ajmaline. J Nat Prod 2001 May;64(5):686-7
alkaloid G  0   Ajmaline/*analogs & derivatives. Org Lett 2001 Feb 8;3(3):345-8
17-acetylrauglucine  119329-01-0   Ajmaline/*analogs & derivatives Plant Extracts. Z Naturforsch (C) 1988;43(7-8):479
detajmium  47719-70-0   Ajmaline/*analogs & derivatives.
Pharma Action Anti-Arrhythmia Agents 		Z Gesamte Inn Med 1982;37(1b):519
ajmaline phenylbarbiturate  81424-61-5 Ajmalan-17,21-diol, (17R,21alpha)-, mixt. with 5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione  *Ajmaline *Barbiturates Drug Combinations. Clin Ter 1981;99(2):155
pulsnorma  78571-97-8 Ajmalan-17,21-diol, (17R,21alpha)-, mixt. with 4,5-dihydro-N-phenyl-N-(phenylmethyl)-1H-imidazole-2-methanamine monohydrochloride, 5-ethyl-5-(1-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione and (7S-(7alpha,7aalpha,14alpha,14abeta))-dodecahydro-7,14-meth  *Ajmaline *Antazoline *Phenobarbital *Sparteine Drug Combinations. Klin Med (Mosk) 53(7):57;1975
dichloroacetylajmaline  2800-66-0 Ajmalan-17,21-diol, bis(chloroacetate) (ester), (17R,21alpha)  Ajmaline/*analogs & derivatives. Boll Soc Ital Cardiol 17(11):1105;1972
herbadine  38485-12-0   *Vinca Alkaloids Ajmaline/*analogs & derivatives. J Pharmaceut Sci 64(2):341;1975
17-monochloroacetylajmaline  47562-08-3   Ajmaline/*analogs & derivatives. Ann Cardiol Angeiol 23(6):539;1974; Boll Soc Ital Cardiol 18(12):1268;1973; Boll Soc Ital Cardiol 18(12):1273;1973; J Pharm Sci 64(4):643;1975; Minn Med 65(41):2537;1974; Sem Hop Paris 1975;50(10):635
bis(monochloroacetyl)ajmaline  2552-89-8   Ajmaline/*analogs & derivatives. Minerva Cardioangiol 21(7):513;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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