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Arecoline

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Definition: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.     
Pharmacological Action Cholinergic Agonists 		Other names Methylarecaidin; Arecolin; Arecholine; Arecholin; Arecaline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-mercapto-1-methylnipecotic acid methyl ester  0   *Sulfhydryl Compounds Arecoline/*analogs & derivatives. Biochem Pharmacol 2007 Feb 15;73(4):561-73
1-methylnipecotic acid 1-oxide methyl ester  0   *Cyclic N-Oxides Arecoline/*analogs & derivatives. Biochem Pharmacol 2007 Feb 15;73(4):561-73
1-methyl-3,4-dehydropiperidine-3-carboxaldehyde  0   Arecoline/*analogs & derivatives. Biochem Pharmacol 2007 Feb 15;73(4):561-73
arecoline 1-oxide  0   *Cyclic N-Oxides Arecoline/*analogs & derivatives. Biochem Pharmacol 2007 Feb 15;73(4):561-73
arecaidine but-2-ynyl ester tosylate  0   Arecoline/*analogs & derivatives. BMC Neurosci 2004 Jul 13;5(1):23
isoarecolone  100752-88-3   Arecoline/*analogs & derivatives. Neuroreport 1995 May 30;6(8):1223-7
norarecoline  495-19-2   Arecoline/*analogs & derivatives. J Med Chem 1995 Jun 9;38(12):2188-95
isoarecolone methiodide  100752-86-1   Arecoline/*analogs & derivatives. Neuropharmacology 1987;26(7A):789
isoarecoline methiodide  52632-31-2 Pyridinium, 1,2,3,6-tetrahydro-4-(methoxycarbonyl)-1,1-dimethyl-, iodide  Arecoline/*analogs & derivatives. Eur J Pharmacol 1986;120(1):127
arecolone methiodide  87453-64-3 Pyridinium, 3-acetyl-1,2,5,6-tetrahydro-1,1-dimethyl-, iodide  Arecoline/*analogs & derivatives Receptors, Nicotinic/drug effects. Mol Pharmacol 1983;23(2):337
arecoline methiodide  4554-30-7   Arecoline/*analogs & derivatives Receptors, Nicotinic/drug effects. Mol Pharmcol 1983;23(2):337
drocarbil  900-77-6   *Arecoline *Arsenicals Drug Combinations. J Am Vet Med Assoc 1980;177(9):759
arecaidine  499-04-7 1,2,5,6-tetrahydro-1-methylnicotinic acid  Arecoline/*analogs & derivatives. Brain Res 136(3):513;1977
arecaidine esters  0   Arecoline/*analogs & derivatives. Prog Brain Res 47:131;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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