Definition: An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
/defic: consider also CITRULLINEMIA
See AlsoCitrullinemia
Other names Synthetase, Argininosuccinate; Synthase, Argininosuccinate; Argininosuccinate Synthetase