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Asparagine

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Definition: A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)  /biosyn /physiol permitted    Other names L-Asparagine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(9H-fluoren-9-yl)methoxycarbonylamino-3-ethoxy-N-tritylsuccinamic acid  0   *Fluorenes Asparagine/*analogs & derivatives. Amino Acids 2010 Jun;39(1):161-5
legumain probe-1  0   *Epoxy Compounds Asparagine/*analogs & derivatives. ACS Chem Biol 2010 Feb 19;5(2):233-43
N(delta)-carbamoylasparagine  0   Asparagine/*analogs & derivatives. J Org Chem. 2008 Oct 17;73(20):7889-94
N-phoshponacetylisoasparagine  0   *Phosphonic Acids Asparagine/*analogs & derivatives. J Med Chem 2006 Oct 5;49(20):5932-8
poly(hydroxyethyl-L-asparagine)  0   Asparagine/*analogs & derivatives. Bioconjug Chem. 2006 May-Jun;17(3):860-4
sequinavir  0   *Quinolines Asparagine/*analogs & derivatives. Spine 2005 Sep 1;30(17):E524-7
Man2GlcNAc2-Asn  0   *Oligosaccharides Asparagine/*analogs & derivatives. Glycobiology 2005 Jan;15(1):79-85
N-hydroxy-2-(cyclopropylmethylamino)-4-((2-hydroxyindan-1-yl)amino)-3-((3-hydroxyphenyl)methyl)-4-oxobutanamide  0   *Hydroxamic Acids Asparagine/*analogs & derivatives. J Med Chem 2001 Oct 11;44(21):3347-50
benzyloxycarbonyl-asparagine  0   Asparagine/*analogs & derivatives Apoptosis/antagonists & inhibitors. Mol Pharmacol 1999 Mar;55(3):548-56
2-(((1-(N-carboxycarbonylamino-4-phosphonomethylphenylalanyl)cyclohex-1-yl)carbonyl)amino)-N-(3-(1-naphthyl)propyl)asparaginamide  0   *Phosphonic Acids Asparagine/*analogs & derivatives. J Med Chem 1999 Jan 14;42(1):25-35
glucosylasparagine  0   Asparagine/*analogs & derivatives. J Cell Biol 1994 Mar;124(6):1071-81
KNI 174  141804-42-4   *Thiazolidines Asparagine/*analogs & derivatives. Biopharm Drug Dispos 1993 Apr;14(3):199-207
T-8801 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparagine Cytarabine Etoposide Methotrexate Vincristine 6-Mercaptopurine. Am J Pediatr Hematol Oncol 1993 Feb;15(1):99-104
(mannose)6-(N-acetylglucosamine)2-asparagine  39114-02-8   *Oligosaccharides Asparagine/*analogs & derivatives. Histochem J 1991 Jul;23(7):303-11
N-(2,3-dihydroxypropyl)asparagine  142421-00-9   Asparagine/*analogs & derivatives. Chem Res Toxicol 1991;4(3):359
2,4-dihydroxyphenylacetylasparaginyl cadaverine  112111-38-3   Asparagine/*analogs & derivatives Cadaverine/*analogs & derivatives. Neurosci Res 1987;5(1):82
2,4-dihydroxyphenylacetylasparaginyl spermine  0   Asparagine/*analogs & derivatives Spermine/*analogs & derivatives. Neurosci Res 1987;5(1):82
2,4-dihydroxyphenylacetylasparagine  111872-98-1   Asparagine/*analogs & derivatives. Neurosci Lett 1987;81(1-2):199
gamma-N-methylasparagine  0   Asparagine/*analogs & derivatives Phycocyanin Plant Proteins. J Biol Chem 1987;262(36):17350
3-hydroxyasparagine  16712-79-1   Asparagine/*analogs & derivatives. Proc Natl Acad Sci USA 1987;84(2):368
asparaginyl-N-acetylgalactosamine  100991-94-4   Acetylgalactosamine/*analogs & derivatives Asparagine/*analogs & derivatives. J Biol Chem 1986;261(3):1020
fucosyl-N-acetylglucosaminylasparagine  62203-19-4 L-Asparagine, N-(2-(acetylamino)-2-deoxy-6-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-glucopyranosyl)-, (Z)  Asparagine/*analogs & derivatives Fucose/*analogs & derivatives. Cancer Res 1984;44(10):4476
arginine N-acetylasparaginate  4584-43-4   Arginine/*analogs & derivatives Asparagine/*analogs & derivatives. Arch Int Physiol Biochim 1982;90(3):201
dansyl asparagine  1100-23-8   *Dansyl Compounds Asparagine/*analogs & derivatives. Anal Biochem 1981;113((1):93
(Man)5(GlcNAc)2Asn  38784-68-8 L-Asparagine, N-(O-alpha-D-mannopyranosyl-(1-3)-O-(O-alpha-D-mannopyranosyl-(1-3)-O-(alpha-D-mannopyranosyl-(1-6))-alpha-D-mannopyranosyl-(1-6))-O-beta-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-b  *Oligosaccharides Asparagine/*analogs & derivatives. J Biol Chem 1981;256(3):1088
D-mannopyranosyl-(1-6)-D-mannopyranosyl-(1-4)-2-acetamido-2-deoxy-D-glucopyranosyl-(1-4)-2-acetamido-1-N-(4'-L-aspartyl)-2-deoxy-beta-D-glucopyranosylamine  76333-26-1 L-Asparagine, N-(O-D-mannopyranosyl-(1-6)-O-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl)  *Oligosaccharides Asparagine/*analogs & derivatives. J Lab Clin Med 1980;96(5):838
N-acetylasparagine  4033-40-3   Asparagine/*analogs & derivatives. Ukr Biokhim Zh 1980;52(5):564
beta-aspartylhydroxamic acid  20154-32-9 DL-asparagine, N-hydroxy  Asparagine/*analogs & derivatives.
Pharma Action Antineoplastic Agents ; Antiviral Agents 		J Biol Chem 1980;255(10):4808
beta-fluoroasparagine  72016-54-7 Asparagine, 3-fluoro-, erythro  Asparagine/*analogs & derivatives. J Med Chem 1980;23(1):85
N(4)-ethylasparagine  7195-20-2 L-Asparagine, N-ethyl  Asparagine/*analogs & derivatives. Biochem J 170:487;1978
beta-aspartyl methylamide  7175-34-0 L-Asparagine, N-methyl  Asparagine/*analogs & derivatives. Biochem Pharmacol 26(15):1405;1977
thioasparagine  58208-26-7 Butanoic acid, 2,4-diamino-4-thioxo-, (S)  *Amino Acids, Sulfur Asparagine/*analogs & derivatives. J Org Chem 41(8):1336;1976
beta-methyl-asparagine  50817-24-8   Asparagine/*analogs & derivatives. J Biol Chem 248(5):1741;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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