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Autoantigens

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Definition: Endogenous tissue constituents that have the ability to interact with AUTOANTIBODIES and cause an immune response.     
Examples Centromere Protein B; Desmoglein 1; Desmoglein 3; Heymann Nephritis Antigenic Complex; snRNP Core Proteins 		Other names Self-Antigens; Autologous Antigens; Self Antigens; Antigens, Autologous
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
trinucleotide repeat containing 6a protein, mouse  0   *Autoantigens. J Biol Chem. 2012 Feb 17;287(8):5979-87.
TNRC6A protein, zebrafish  0   *Autoantigens *Zebrafish Proteins. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1104-9
Sdccag8 protein, rat  0   *Autoantigens. Biosci Biotechnol Biochem 2010 Jul 23;74(7):1466-9
p140 autoantigen, human  0   *Autoantigens. Arthritis Rheum. 2009 Jun;60(6); 1807-14
postmeiotic segregation increased 1 antigen, human  0   *Autoantigens Anemia, Aplastic. Br J Haematol 2008 Jul;142(3):427-35
kallikrein 1b22, mouse  EC 3.4.21.-   *Autoantigens *Kallikreins. Invest Ophthalmol Vis Sci 2009 May;50(5):2245-54
melanin-associated antigen, rat  0   *Autoantigens. Am J Pathol 2008 Nov;173(5):1440-54
Hom s 2 autoantigen, human  0   *Autoantigens. J Invest Dermatol 2008 Jun;128(6):1451-9
NALP5 protein, human  0   *Autoantigens. N Engl J Med. 2008 Mar 6;358(10):1018-28
prostatic steroid binding protein, mouse  0   *Autoantigens *Prostatein. J Immunol 2007 Aug 1;179(3):1559-67
testis-specific antigen 70, rat  0   *Autoantigens *Cytoskeletal Proteins. Biochem Biophys Res Commun 2007 Mar 9;354(2):528-34
RegII protein, mouse  0   *Autoantigens. Diabetes 2007 Jan;56(1):34-40
Mea1 protein, mouse  0   *Autoantigens *Membrane Proteins.
MEA1 protein, human  0   *Autoantigens *Membrane Proteins.
Golga3 protein, mouse  0   *Autoantigens *Membrane Proteins.
RNA-associated protein 55, human  0   *Ribonucleoproteins Autoantigens. RNA 2006 Apr;12(4):547-54
testis-specific antigen 70, mouse  0   *Autoantigens. J Androl 2005 Nov-Dec;26(6):761-71
Brsk2 protein, human  EC 2.7.1.37   *Protein-Serine-Threonine Kinases Autoantigens. J Neuroimmunol 2005 Dec 30;170(1-2):186-90
LA protein, human (349-364)  0   *Autoantigens *Peptide Fragments. Clin Exp Immunol 2005 Oct;142(1):172-9
KLHL7 protein, human  0   *Autoantigens. Immunology 2005 Sep;116(1):53-63
KIAA0430 protein, human  0   *Autoantigens. Clin Exp Immunol 2005 Jun;140(3):556-63
KIAA1524 protein, human  0   *Autoantigens *Membrane Proteins Tumor Markers, Biological. Prostate 2005 May 15;63(3):252-8
golgin-84, rat  0   *Autoantigens *Membrane Proteins Golgi Apparatus. Science 2005 Feb 18;307(5712):1095-8
Cldn11 protein, mouse  0   *Nerve Tissue Proteins Autoantigens.
rop-1 protein, C elegans  0   *Autoantigens *Ribonucleoproteins *RNA, Small Cytoplasmic *Caenorhabditis elegans Proteins.
Ro60 autoantigen, Xenopus  0   *Autoantigens *Ribonucleoproteins *RNA, Small Cytoplasmic *Xenopus Proteins.
Ssa2 protein, mouse  0   *Autoantigens *Ribonucleoproteins *RNA, Small Cytoplasmic.
Ccl2 protein, mouse  0   *Chemokine CCL2 Autoantigens Cytokines.
Ccl2 protein, rat  0   *Chemokine CCL2 Autoantigens Cytokines.
SOX13 protein, human  0   *Autoantigens *SOXD Transcription Factors Leucine Zippers.
Spa17 protein, mouse  0   *Carrier Proteins Autoantigens.
ric-19 protein, C elegans  0   *Autoantigens *Caenorhabditis elegans Proteins Nerve Tissue Proteins.
Ica1 protein, rat  0   *Autoantigens Nerve Tissue Proteins.
Ica1 protein, mouse  0   *Autoantigens Nerve Tissue Proteins.
Exosc10 protein, mouse  0   *Nuclear Proteins Autoantigens.
SMB protein, S cerevisiae  0   *Autoantigens *Ribonucleoproteins, Small Nuclear *Saccharomyces cerevisiae Proteins.
NASPP1 protein, human  0   *Autoantigens *Nuclear Proteins Carrier Proteins Gonadal Steroid Hormones.
NASP protein, human  0   *Autoantigens *Nuclear Proteins Carrier Proteins Gonadal Steroid Hormones.
metaphase chromosome protein 1, human  0   *Autoantigens. Chromosome Res 2000;8(8):699-711
Golga4 protein, mouse  0   *Autoantigens *Membrane Proteins.
Strn3 protein, mouse  0   *Autoantigens *Calmodulin-Binding Proteins Nuclear Proteins Cell Cycle Proteins.
Gs2na protein, rat  0   *Autoantigens *Calmodulin-Binding Proteins Nuclear Proteins Cell Cycle Proteins.
XMAN1 protein, Xenopus  0   *Membrane Proteins *Nuclear Proteins *Xenopus Proteins Autoantigens.
Ce-MAN1 protein, C elegans  0   *Membrane Proteins *Nuclear Proteins *Caenorhabditis elegans Proteins Autoantigens.
Mrps31 protein, mouse  0   *Autoantigens *Ribosomal Proteins.
liver cytosol antigen type 1, rat  0   *Autoantigens.
Cdr1 protein, mouse  0   *Nerve Tissue Proteins Autoantigens Tumor Markers, Biological.
Dlat protein, rat  EC 2.3.1.12   *Autoantigens *Mitochondrial Proteins *Dihydrolipoyllysine-Residue Acetyltransferase.
Sval3 protein, mouse  0   *Autoantigens *Seminal Plasma Proteins. Gene 2004 Jan 21;325:179-86
SPTRX-2 protein, rat  0   *Thioredoxins *Seminal Plasma Proteins Autoantigens. J Biol Chem 2003 Nov 7;278(45):44874-85
SPTRX-2 protein, mouse  0   *Thioredoxins *Seminal Plasma Proteins Autoantigens. J Biol Chem 2003 Nov 7;278(45):44874-85
Sdccag8 protein, mouse  0   *Autoantigens *Neoplasm Proteins. Gene 2003 Jan 16;303:35-46
SDCCAG8 protein, human  0   *Autoantigens *Neoplasm Proteins. Gene 2003 Jan 16;303:35-46
ASRGL1 protein, human  EC 3.5.1.-   *Asparaginase *Autoantigens. Mol Reprod Dev 2002 Jun;62(2):233-47
Asrgl1 protein, rat  EC 3.5.1.1   *Asparaginase *Autoantigens. Mol Reprod Dev 2002 Jun;62(2):233-47
autoantigen GW182, human  0   *Autoantigens *RNA-Binding Proteins. Mol Biol Cell 2002 Apr;13(4):1338-51
early endosome antigen 2, human  0   *Membrane Proteins Autoantigens. Immunology 2002 Jul;106(3):336-42
Golgi complex autoantigen, 97-kDa  0   *Autoantigens Sjogren's Syndrome. Arthritis Rheum 1997 Sep;40(9):1693-702
TRIM68 protein, human  0   *Autoantigens *Ubiquitin-Protein Ligases. J Clin Invest 2001 Sep;108(6):861-9
cell division autoantigen-1  0   *Autoantigens. J Biol Chem 2001 Sep 7;276(36):33665-74
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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