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Azauridine

More information in Books or onNLM PubMed
Definition: A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic.     
Pharmacological Action Antimetabolites, Antineoplastic; Dermatologic Agents 		Other names 6 Azauridine; 6-Azauridine; 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-d
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
azaribine  2169-64-4   Azauridine/*analogs & derivatives. J Am Acad Dermatol 1985;13(4):567
6-azauridine 5'-triphosphate  6198-30-7   Azauridine/*analogs & derivatives Uridine Triphosphate/*analogs & derivatives. J Biol Chem 1980;255(18):8402
3-deaza-6-azauridine  56707-91-6 3(2H)-Pyridazinone, 5-hydroxy-2-beta-D-ribofuranosyl  Azauridine/*analogs & derivatives. Biochim Biophys Acta 520(1):229;1978
2-thio-6-azauridine  27089-56-1   Azauridine/*analogs & derivatives Thiouridine/*analogs & derivatives. Cancer Chemother Rep 58(3):345;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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