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Anion Exchange Protein 1, Erythrocyte

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Definition: A ubiquitous membrane transport protein found in the plasma membrane of diverse cell types and tissues, and in nuclear, mitochondrial, and Golgi membranes. It is the major integral transmembrane protein of the erythrocyte plasma membrane, comprising 25% of the total membrane protein. It exists as a dimer and performs the important function of allowing the efficient transport of bicarbonate across erythrocyte cell membranes in exchange for chloride ion.      Other names Erythrocyte Membrane Band 3 Protein; Erythrocyte Anion Transport Protein; Band 3 Protein; Anion Transport Protein, Erythrocyte; Protein, Band III; Protein, Band 3; Chloride-Bicarbonate Exchanger, AE1; Anion Exchanger, Erythrocyte; AE1 Cl HCO3 Exchanger; AE1 Chloride Bicarbonate Exchanger; Protein Band 3; Erythrocyte Membrane Anion Transport Protein; Erythrocyte Anion Exchanger; Capnophorin; Band III Protein; AE1 Gene Product; AE1 Cl- HCO3- Exchanger; AE1 Chloride-Bicarbonate Exchanger; AE1 Anion Exchanger
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Slc4a1 protein, mouse  0   *Anion Exchange Protein 1, Erythrocyte. Nature 1985 Jul 18-24;316(6025):234-8
SLC4A1 protein, human  0   *Anion Exchange Protein 1, Erythrocyte Blood Group Antigens. Am J Physiol Renal Physiol 2002 May;282(5):F810-20
band 3 protein Walton  0   *Anion Exchange Protein 1, Erythrocyte. Blood 2002 Jan 1;99(1):342-7
4-trimethylammonium-4'-isothiocyanostilbene-2,2'-disulfonic acid  0   *Stilbenes *Sulfonic Acids Anion Exchange Protein 1, Erythrocyte/antagonists & inhibitors. Biochemistry 1999 Aug 24;38(34):11172-9
band 3, Campinas  0   *Anion Exchange Protein 1, Erythrocyte Spherocytosis, Hereditary. Blood 1997 Oct 1;90(7):2810-8
band 3 protein Memphis variant II  0   *Anion Exchange Protein 1, Erythrocyte. Biochem J 1996 Jul 15;317( Pt 2):509-14
pfalhesin  0   *Anion Exchange Protein 1, Erythrocyte Cell Adhesion. Exp Parasitol 1994 Mar;78(2):203-9
band 3 protein Tuscaloosa  0   *Anion Exchange Protein 1, Erythrocyte. Blood 1992 Jul 15;80(2):523-9
band 3 protein Memphis  0   *Anion Exchange Protein 1, Erythrocyte. Blood 1991;78(4):1117
senescent cell differentiation antigen  0   *Antigens, Differentiation Autoantigens Anion Exchange Protein 1, Erythrocyte Cell Death. Prog Clin Biol Res 1985;195:251
erythroglycan  0   *Anion Exchange Protein 1, Erythrocyte. J Biol Chem 1980;255(8):3266; J Biol Chem 253(22):8006;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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