encyclopedia of medical concepts
ψ 

Benzamidines

More information in Books or onNLM PubMed
Definition: Amidines substituted with a benzene group. Benzamidine and its derivatives are known as peptidase inhibitors.  peptidase inhib   
Examples Diminazene; Pentamidine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
APDDR-0901  0   *Benzamidines *Plant Extracts *Vitamin A Acne Vulgaris/drug therapy. Eur J Dermatol. 2011 Nov-Dec;21(6):959-65
N-propyl-4-(4-(5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl)piperazin-1-yl)benzamidine  0   *Benzamidines *Thiadiazoles. Eur J Med Chem 2011 Jun;46(6):2602-8
1,2-ethane bis-1-amino-4-benzamidine  0   *Benzamidines. Eur J Med Chem. 2010 Jul;45(7):3101-10
4-trifluoromethoxy-N-(2-trifluoromethylbenzyl)benzamidine  0   *Benzamidines Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors. Brain Res Bull 2009 Feb 16;78(2-3):85-90
hexamidine diisethionate  0   *Benzamidines. Int J Toxicol 2007;26 Suppl 3():79-88
DB359  0   *Benzamidines. J Am Chem Soc 2007 Jul 4;129(26):8389-95
RT29 compound  0   *Benzamidines *Benzimidazoles. Biochemistry 2007 Jun 12;46(23):6944-56
DB569 compound  0   *Benzamidines. J Antimicrob Chemother 2006 Sep;58(3):610-4
4-tetradecyloxybenzamidine  0   *Benzamidines. Eur J Med Chem. 2005 Sep;40(9):850-61
N-methoxy-6-(5-(4-(N-methoxyamidino)phenyl)furan-2-yl)nicotinamidine  0   *Benzamidines *Furans. Xenobiotica 2005 Mar;35(3):211-26
6-(5-(4-amidinophenyl)furan-2-yl)nicotinamidine  0   *Benzamidines *Furans. Xenobiotica 2005 Mar;35(3):211-26
4-(2-(3-aminobenzenesulfonylamino)-1-(3,5-diethoxy-2-fluorophenyl)-2-oxoethylamino)-2-hydroxybenzamidine  0   *Benzamidines *Sulfonamides Factor VIIa/antagonists & inhibitors. J Biol Chem 2005 Mar 11;280(10):9160-9
propylsulfonamide-threonyl-methionyl-4-aminobenzamidine  0   *Benzamidines *Dipeptides Factor VIIa/antagonists & inhibitors. Biochem Biophys Res Commun 2004 Nov 26;324(4):1227-33
3-(4-(5-(2,6-dimethylpiperidin-1-yl)pentyl)-3-oxo-3,4-dihydroxyquinoxalin-2-yl)benzamidine  0   *Benzamidines *Quinoxalines Factor Xa/antagonists & inhibitors. J Med Chem 2004 Jul 29;47(16):4089-99
pafuramidine  0   *Benzamidines Antifungal Agents Pneumonia, Pneumocystis Pneumocystis jirovecii. Rapid Commun Mass Spectrom 2002;16(11):1078-85
3,5-dipentadecyloxybenzamidine hydrochloride  0   *Benzamidines *Fatty Acids. Pharm Res 2001 Sep;18(9):1284-98
N,N'-diphenyl-4-methoxybenzamidine  0   *Benzamidines. Arzneimittelforschung 2001 Nov;51(11):920-3
amidinophenyl ester  0   *Benzamidines. Comp Biochem Physiol B Biochem Mol Biol 2000 Nov;127(3):337-46
N-(3-(2-pyridinyl)isoquinolin-1-yl)benzamidine  0   *Benzamidines *Isoquinolines Ligands Receptors, Purinergic P1/antagonists & inhibitors. J Med Chem 1998 Oct 8;41(21):3987-93
ethyl N-(3-(2-fluoro-4-(thiazolidin-3-yl(imino)methyl)benzoyl)amino-2,2-dimethylpentanoyl)piperidine-4-acetate  0   *Benzamidines *Piperidines *Thiazolidines Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors. J Med Chem 1998 Jun 18;41(13):2345-60
ethyl N-allyl-N-(2-methyl-3-(4-(4-amidinophenoxycarbonyl)phenyl)propenoyl)aminoacetate methanesulfonate  0   *Benzamidines Allylglycine/*analogs & derivatives. Anticancer Res 1996 Jul-Aug;16(4A):1823-6
3-(naphthalene-2-sulfonylamino)-1-(2-(4-amidinophenyl)-1-piperidinocarbonylethyl)-2-pyrrolidinone  0   *Benzamidines *Pyrrolidinones. J Enzyme Inhib 1995;9(1):73-86
SC 54701A  0   *Benzamidines. Circulation 1996 Jan 1;93(1):129-34
N-methylbenzamidine  34028-17-6   *Benzamidines. Xenobiotica 1995 May;25(5)443-55
N-(3-(4-(4-(amidinophenoxy)carbonyl)phenyl)-2-methyl-2-propenoyl)-N-allylglycine  0   *Benzamidines Allylglycine/*analogs & derivatives. Biochemistry 1995 Oct 3;34(39):12849-53
xemilofiban  149820-74-6 4-Pentynoic acid, 3-004-004-(((aminoiminomethyl)phenyl)amino)-((1,4-dioxobutyl)amino)-, ethyl ester, (S)  *Benzamidines.
Pharma Action Platelet Aggregation Inhibitors 		Circulation 1995 Jan 15;91(2):403-10
4-diazoniumbenzamidine  54114-66-8   *Benzamidines *Diazonium Compounds. J Biol Chem 1993 Dec 25;268(36):26893-903
4'-amidinophenyl-4-chloroanthranilic acid  144262-66-8   *Anthranilic Acids *Benzamidines. Circulation 1992 Aug;86(2):548-52
3,4,5-trihydroxybenzamidoxime  0   *Benzamidines Ribonucleotide Reductases/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors ; Free Radical Scavengers 		Ann Thorac Surg 1992 Jun;53(6):1091-5
1,3-bis(4-amidinophenoxy)-2-(4-amidinophenoxymethyl)ethylpropane  115044-37-6   *Benzamidines. Farmaco 1991 Nov;46(11):1297-1310
1,3-bis(4-amidino-2-methoxyphenoxy)propane  124076-65-9   *Benzamidines. J Med Chem 1990;33(4):1252
4,4'-((2,2-bis((4-(aminoiminomethyl)-2-iodophenoxy)methyl)-1,3-propanediyl)bis(oxy))bis(3-iodobenzenecarboximidamide)  94854-85-0   *Benzamidines. Thromb Res 1989;56(3):417
4,4'-(2,2-bis((4-(aminoiminomethyl)-2-bromophenoxy)methyl)-1,3-propanediyl)bis(oxy))bis(3-bromobenzenecarboximidamide  94883-66-6   *Benzamidines. Clin Exp Metastasis 1989;7(1):25
1,3-di-(4-amidinophenoxy)-2,2-bis-(4-amidinophenoxymethyl)propane  82332-92-1   *Benzamidines. Clin Exp Metastasis 1989;7(1):25
dibrompropamidine  496-00-4   *Benzamidines.
Pharma Action Anti-Infective Agents, Local 		Br J Ophthalmol 71(7):500
benzamidoxime  613-92-3   *Benzamidines. Xenobiotica 1987;17(6):659
2-tosylamino-4-phenylbutyryl-4-amidinoanilide  92953-76-9   *Benzamidines *Tosyl Compounds. Pharmazie 1987;42(2):109
4-amidinophenyl 2-methylcinnamate  103499-68-9   *Benzamidines *Cinnamates. Biochemistry 1986;25(17):4929
4-amidinophenyl cinnamate  103499-67-8   *Benzamidines *Cinnamates. Biochemistry 1986;25(17):4929
2-(4-amidinophenyl)-1-benzofuran-5-carboxamidine  47165-00-4   *Benzamidines. J Chromatogr 1986;378(1):183
propamidine isethionate  140-63-6   *Benzamidines.
Pharma Action Antiprotozoal Agents 		J Med Microbiol 1985;20(2):139
N-(3-methylphenyl)-N'-cyanobenzamidine  80949-07-1 Benzenecarboximidamide, N-cyano-N'-(3-methylphenyl)  *Benzamidines. Pharmazie 1981;36(11):757
furamidine  73819-26-8   *Benzamidines Antifungal Agents. Exp Parasitol 1982;53(1):133
1,4-bis(3,3'-amidinophenoxymethyl)cyclohexane dilactate  81142-50-9 Propanoic acid, 2-hydroxy-, (S)-, compd. with 3,3'-(1,4-cyclohexanediylbis(methyleneoxy))bis(benzenecarboximidamide) (2:1)  *Benzamidines. Acta Med Okayama 1981;35(5):327
benzamidine  618-39-3   *Benzamidines.
Pharma Action Serine Proteinase Inhibitors 		Clin Chem 1981;27(10):1690
1,2-di(5-amidino-2-benzofuranyl)ethane  66639-67-6 5-Benzofurancarboximidamide, 2,2'-(1,2-ethanediyl)bis  *Benzamidines. Thromb Res 1980;19(3):339
3-nitrobenzamidine  3459-99-2 benzenecarboximidamide, 3-nitro  *Benzamidines. Cancer Clin Trials 1980;3(1):55
hexamidine  3811-75-4 Benzenecarboximidamide, 4,4'-(1,6-hexanediylbis(oxy))bis  Benzamidines.
Pharma Action Anti-Infective Agents 		Contact Dermatitis 4(6):375;1978
azidobenzamidine  0   *Azides *Benzamidines. J Biol Chem 253(6):1846;1978
3-(2-(2-chloro-5-fluorosulfonylphenylureido)phenoxybutoxy)benzamidine  32919-84-9 Benzenesulfonyl fluoride, 3-((((2-(4-(3-(aminoiminomethyl)phenoxy)butoxy)phenyl)amino)carbonyl)amino)-4-chloro  *Benzamidines. Biochemistry 17(26):5713;1978; J Biol Chem 252(22):8027;1977
4-toluamidine  18465-11-7 4-methylbenzenecarboximidamide  *Benzamidines. Biochim Biophys Acta 481(1):164;1977
3-propoxybenzamidine  26130-50-7   *Benzamidines. J Biol Chem 248(24):8323;1973
3-(3-(4-nitrophenylureido)phenoxypropoxy)benzamidine  23604-33-3   *Benzamidines. Immunology 26(4):819;1974
4-nitrobenzoic acid 4'-amidinoanilide  0   *Benzamidines. Thromb Haemost 31(1):172;1974
4-aminobenzoic acid 4'-amidinoanilide  53032-85-2   *Benzamidines. Thromb Diath Haemorrh 31(1):172;1974
4-aminobenzamidine  3858-83-1   *Benzamidines Acrosin/antagonists & inhibitors.
Pharma Action Antineoplastic Agents ; Trypsin Inhibitors ; Serine Proteinase Inhibitors 		Biochim Biophys Acta 526(1):202;1978; Biol Reprod 17:131;1977; Eur J Biochem 88(1):183;1978; Hoppe-Seyler Z Physio Chem 357(2):207;1976; J Exptl Eurl 199(1):149;1977
4-amidinophenylbenzoate  50466-20-1   *Benzamidines. Acta Biol Med Germ 32(5):435;1974
4-amidinobenzoic acid 3',4'-dimethoxyanilide  53032-89-6   *Benzamidines. Thromb Diath Haemorrh 31(1):172;1974
4-amidinobenzoic acid anilide  50466-26-7   *Benzamidines. Thromb Diath Haemorrh 31(1):172;1974
propamidine  104-32-5   *Benzamidines.
Pharma Action Antiprotozoal Agents 		Br Med J 2(6050):1505;1976
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy