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Benzoflavones

More information in Books or onNLM PubMed
Definition: Organic compounds containing a benzene ring attached to a flavone group. Some of these are potent arylhydrocarbon hydroxylase inhibitors. They may also inhibit the binding of nucleic acids to benzopyrenes and related compounds. The designation includes all isomers; the 7,8-isomer is most frequently encountered.  enzyme inhib   
Pharmacological Action Enzyme Inhibitors
Examples beta-Naphthoflavone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3',4'-dimethoxy-alpha-naphthoflavone  0   *Benzoflavones. Mol Pharmacol 2011 Mar;79(3):508-19
2-pyridin-7,6-benzoflavone  0   *Benzoflavones. J Membr Biol 2007 Dec;220(1-3):1-9
7,8-benzoflavone-5,6-oxide  0   *Benzoflavones. Xenobiotica 1994 Nov;24(11):1053-62
alpha-naphthoflavone-DNA adduct  0   *Benzoflavones *DNA Adducts. Carconogenesis 1991;12(3):385
4'-benzyloxy-3'-methoxy-7,8-benzoflavone  131612-93-6   *Benzoflavones. Pharmacology 1985;31(4):194
alpha-naphthoflavone-7,8-dihydrodiol  86126-12-7 4H-Naphtho(1,2-b)pyran-4-one, 7,8-dihydro-7,8-dihydroxy-2-phenyl-, trans  *Benzoflavones. Carcinogenesis 1983;4(4):425
alpha-naphthoflavone-5,6-dihydrodiol  78729-84-7   *Benzoflavones. Carcinogenesis 1983;4(4):425
9-hydroxy-alpha-naphthoflavone  78729-83-6   *Benzoflavones. Toxicol Lett 1982;14(1-2):7
alpha-naphthoflavone  604-59-1   *Benzoflavones. Biochem Biophys Res Commun 84(3):706;1978; Biochem Pharmacol 25(19):2187;1976; Cancer Lett 5(5):261;1978; Cancer Res 1979;39(11):4612; Cancer Res 1979;39(11):4620; Cancer Res 35(12):3731;1975; Cancer Res 38(8):2501;1978; Cancer Res 39(3):1083;1979; JNCI 60(2):405;1978; Life Sci 1980;26(4):316; Mol Pharmacol 1979;15(3):720; Monogr Hum Genet 10:165;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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