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Bile Acids and Salts

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Definition: Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.     
Pharmacological Action Gastrointestinal Agents
Examples Cholic Acids 		Other names Bile Salts; Salts, Bile; Acids, Bile; Bile Acids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tauromantellic acid  0   *Bile Acids and Salts. J Nat Prod. 2012 Mar 23;75(3):473-8
cholestenoic acid  0   *Cholestenes Bile Acids and Salts. Aging Cell 2006 Aug;5(4):283-91
S 0960  142974-51-4   *Bile Acids and Salts. Arzneimittelforschung. 2003;53(12):837-43
cholebine  0   *Bile Acids and Salts. Atherosclerosis 1997 Mar 21;129(2):241-8
anhydroscymnol  567-68-0   *Cholestanols Bile Acids and Salts. Chem Pharm Bull (Tokyo) 1991 Dec;39(12):3153-6
scymnol  6785-34-8 Cholestane-3,7,12,24,26,27-hexol, (3alpha,5beta,7alpha,12alpha)  *Cholestanols Bile Acids and Salts. Chem Pharm Bull (Tokyo) 1991 Dec;39(12):3153-6
sodium-bile acid cotransporter  145420-23-1   *Symporters *Organic Anion Transporters, Sodium-Dependent Bile Acids and Salts Membrane Glycoproteins Sodium. Proc Natl Acad Sci USA 1991;88(23):10629
3-hydroxy-7-(hydroxyimino)cholanic acid  131204-64-3   *Cholic Acids Bile Acids and Salts. J Pharmacobiodynam 1990;13(9):558
3,7-dihydroxy-5-cholestenoic acid  115538-84-6   *Cholestenes Bile Acids and Salts. J Lipid Res 1989;30(12):1877
trichechol  114882-48-3   *Cholestanols Bile Acids and Salts. Chem Pharm Bull (Tokyo) 1989;37(7):1852
7 alpha-hydroxy-3-oxo-4-cholestenoic acid  115538-85-7   *Cholestenones Bile Acids and Salts. J Lipid Res 1988;29(5):629
phocaecholic acid  105369-89-9   *Bile Acids and Salts. Comp Biochem Physiol (A) 1988;89(2):211
24-(12-hydroxy-3-oxo-4-cholenoyl-5'phospho)-3'phosphoadenosine  115288-28-3   *Cholenes Adenosine Diphosphate/*analogs & derivatives Bile Acids and Salts. J Biol Chem 1987;262(10):4701
3,7,12-trihydroxy-5-cholenoic acid  108906-88-3   *Cholenes Bile Acids and Salts. J Clin Invest 1987;79(4):1031
3,7-dihydroxy-22,23-methylene-cholan-24-oic acid (2-sulfoethyl)amide  93001-12-8   *Cholic Acids Bile Acids and Salts. J Med Chem 1985;28(2):239
tauro-3 beta-hydroxy-5-cholenoate  17238-48-1   *Cholenes Bile Acids and Salts. Gastroenterology 1983;85(3):674
bile acid binding proteins  0   *Carrier Proteins *Membrane Glycoproteins Adenosine Triphosphatases Bile Acids and Salts. J Biol Chem 1983;258(6):3602
3-hydroxyetianic acid  38775-99-4 Androstane-17-carboxylic acid, 3-hydroxy-, (3alpha,5beta,17beta)  *Androstanols Bile Acids and Salts. J Clin Invest 1983;71(1):73
2,3,6,7-tetrahydroxycholanoic acid  83504-21-6 Cholan-24-oic acid, 2,3,6,7-tetrahydroxy  *Cholanes Bile Acids and Salts. Eur J Clin Invest 1982;12(4):301
3,6,7,12-tetrahydroxycholanoic acid  63266-88-6 Cholan-24-oic acid, 3,6,7,12-tetrahydroxy  *Cholanes Bile Acids and Salts. Eur J Clin Invest 1982;12(4):301
1,3,7,12-tetrahydroxycholanoic acid  63266-89-7 Cholan-24-oic acid, 1,3,7,12-tetrahydroxy  *Cholic Acids Bile Acids and Salts. Eur J Clin Inves 1982;12(4):301
3,7,12-trihydroxycholestan-26,29-dioic acid  0   *Cholestanols Bile Acids and Salts. Steroids 1981;37(1):81
3-hydroxycholestan-26-oic acid  0   *Cholestanols Bile Acids and Salts. Steroids 1981;37(1):81
3-hydroxy-5-cholestenoic acid  6561-58-6   Cholesterol/*analogs & derivatives Bile Acids and Salts. Steroids 1981;37(1):81
bile acid sulfates  0   *Bile Acids and Salts. Steroids 34(1):73;1979
keto bile acids  0   *Bile Acids and Salts. J Lipid Res 19:501;1978
glycodihydrofusidate  0   Fusidic Acid/*analogs & derivatives Bile Acids and Salts. Am J Physiol 231(6):1875;1976; Biomedicine 26(1):60;1977; Can J Physiol Pharmacol 56(2):163;1978

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