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Biphenyl Compounds

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Definition:   DF: BIPHENYL CPDS   
Examples Aminobiphenyl Compounds; Benzidines; 3,3'-Diaminobenzidine; Clofenapate; Dianisidine; 3,3'-Dichlorobenzidine; Flurbiprofen; Losartan; Niclofolan; Polybrominated Biphenyls; Polychlorinated Biphenyls 		Other names Compounds, Biphenyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N1-4-((biphenylsulphonyl)amino)phenyl-2-amino-3-phenyl-propionamide  0   *Biphenyl Compounds *Phenylpropionates Antineoplastic Agents Histone Deacetylase Inhibitors. Yao Xue Xue Bao. 2010 Jun;45(6):735-41
5-(3-biphenyl-4-yl-5-ethyl-4H-1,2,4-triazol-4-yl)isoquinoline  0   *Biphenyl Compounds *Isoquinolines. Bioorg Med Chem. 2012 Jan 1;20(1):34-41
4'-methylbiphenyl-2-carbonitrile  0   *Biphenyl Compounds *Nitriles. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb 15;87():273-85
2,2-dimethyl-3,5-dihydroxy-7-(4-hydroxyphenyl)chromane  0   *Biphenyl Compounds. Fitoterapia. 2011 Dec;82(8):1237-40
lagerine N-oxide  0   *Biphenyl Compounds *Cyclic N-Oxides *Quinolizidines. Planta Med. 2011 Dec;77(18):2037-41
lagerstroemine N-oxide  0   *Biphenyl Compounds *Cyclic N-Oxides *Quinolizidines. Planta Med. 2011 Dec;77(18):2037-41
5-epi-dihydrolyfoline N-oxide  0   *Biphenyl Compounds *Cyclic N-Oxides *Quinolizidines. Planta Med. 2011 Dec;77(18):2037-41
decamine N-oxide  0   *Biphenyl Compounds *Cyclic N-Oxides *Quinolizidines Alkaloids. Planta Med. 2011 Dec;77(18):2037-41
oxiran-2-ylmethyl 6-(1,1'-biphenyl-4-yl)hexanoate  0   *Biphenyl Compounds *Epoxy Compounds. J Med Chem. 2012 Jan 26;55(2):824-36.
LDE223  0   *Biphenyl Compounds. Ann Rheum Dis. 2012 Mar;71(3):400-7.
tetrabi  0   *Biphenyl Compounds *Organophosphorus Compounds Ligands. Chemistry. 2011 Dec 16;17(51):14559-63
beta-(4,4'-biphenyl)alanine  0   *Biphenyl Compounds Alanine/*analogs & derivatives. Antimicrob Agents Chemother. 2011 Oct;55(10):4918-21.
4'-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol  0   *Biphenyl Compounds *Tetrahydroisoquinolines. Bioorg Med Chem. 2008 Apr 1;16(7):3732-43.
selaginellin M  0   *Biphenyl Compounds *Cyclohexanones. J Asian Nat Prod Res. 2011 Oct;13(11):1051-5
6,6'-bis(2-((3-chloro-4-fluorophenyl)amino)-2-oxoethoxy)-5,5'-dimethoxy- N,N'-dimethylbiphenyl-2,2'-dicarboxamide  0   *Biphenyl Compounds *Hydrocarbons, Halogenated. Med Chem. 2011 Jul 1;7(4):286-94
2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine  0   *Biphenyl Compounds *Sulfonamides Receptors, Opioid, kappa/antagonists & inhibitors. J Med Chem. 2011 Aug 25;54(16):5868-77.
caesappanin A  0   *Biphenyl Compounds. Fitoterapia. 2011 Jul;82(5):762-6
caesappanin B  0   *Biphenyl Compounds. Fitoterapia. 2011 Jul;82(5):762-6
4-((1E)-3-(biphenyl-4-yl)buta-1,3-dien-1-yl)phenyl 2-methylprop-2-enoate  0   *Biphenyl Compounds *Propionic Acids. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1992-7
4-((1E)-3-(biphenyl-4-yl)buta-1,3-dien-1-yl)phenyl prop-2-enoate  0   *Biphenyl Compounds *Propionic Acids. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1992-7
p-biphenyloxycarbonylphenyl acrylate  0   *Acrylates *Biphenyl Compounds. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1024-33
3-biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-1,2,4-triazole  0   *Biphenyl Compounds *Triazoles. J Med Chem 2011 Jan 13;54(1):387-91
(S)-4'-((5-(1-(4-bromophenyl)ethylcarbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid  0   *Biphenyl Compounds Hypoglycemic Agents. Nature. 2011 Sep 22;477(7365):477-81
(S)-4'-((5-((1-(4-nitrophenyl)ethyl)carbamoyl)-1H-indol-1-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid  0   *Biphenyl Compounds Hypoglycemic Agents. Nature. 2011 Sep 22;477(7365):477-81
LDE225  0   *Biphenyl Compounds *Pyridines. ACS Med Chem Lett 2010; 1(3):130-134
N-(6-((1-((4-fluorobenzyl)(methyl)amino)ethylidene))amino)-2-hydroxy-2,3-dihydro-1H-inden-1-ylbiphenyl-4-carboxamide  0   *Biphenyl Compounds *Indenes Receptor, Muscarinic M1/agonists. J Pharmacol Exp Ther 2011 Aug;338(2):622-32
5-(3',5'-dichlorobiphenyl-4-yl)-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid  0   *Amino Acids *Biphenyl Compounds. Cell 2011 Jun 24;145(7):1075-87
(Z)-ethyl 2-((1-(biphenyl-4-ylmethyl)indol-3-yl) methylene)-7-methyl-3-oxo-5-phenylthiazolo(3,2-a)pyrimidine-6-carboxylate  0   *Biphenyl Compounds *Pyrimidines. ChemMedChem. 2011 May 2;6(5):904-21
1-(6-methoxy-4'-(trifluoromethyl)-3-biphenylyl)-N-(1-phenylethyl)ethanamine  0   *Biphenyl Compounds *Diethylamines. J Pharmacol Exp Ther 2011 Jun;337(3):681-91
2-(2'-(5-ethyl-3,4-diphenyl-1H-pyrazol-1-yl)biphenyl-3-yloxy)acetic acid  0   *Biphenyl Compounds *Pyrazoles Fatty Acid-Binding Proteins/antagonists & inhibitors. Nature 2007 Jun 21;447(7147):959-65
(2E,2'E)-1,1'-(3-hydroxy-5-methylbiphenyl-2,6-diyl)bis(3-(3-chlorophenyl)prop-2-en-1-one)  0   *Alkenes *Biphenyl Compounds. Bioorg Med Chem. 2010 Jul 1;18(13):4711-20
(2E,2'E)-1,1'-(4'-chloro-3-hydroxy-5-methylbiphenyl-2,6-diyl)bis(3-phenylprop-2-en-1-one)  0   *Alkenes *Biphenyl Compounds. Bioorg Med Chem. 2010 Jul 1;18(13):4711-20
ferruginene C  0   *Biphenyl Compounds *Heterocyclic Compounds, 3-Ring. J Nat Prod. 2011 Apr 25;74(4):712-7
fimasartan  247257-48-3   *Biphenyl Compounds *Pyrimidines *Tetrazoles. Int J Clin Pharmacol Ther. 2011 May;49(5):321-7
selaginellin L  0   *Biphenyl Compounds *Cyclohexanones. J Asian Nat Prod Res. 2011 Apr;13(4):356-60
selaginellin K  0   *Biphenyl Compounds *Cyclohexanones. J Asian Nat Prod Res. 2011 Apr;13(4):356-60
3-(4-((2',6'-dimethylbiphenyl-3-yl)methoxy)-2-fluorophenyl)propanoic acid  0   *Biphenyl Compounds *Phenylpropionates. J Med Chem 2011 Mar 10;54(5):1365-78
bis(diphenylphosphate)diimine  0   *Biphenyl Compounds *Imines. J Fluoresc. 2011 Jan;21(1):187-94
AMG 837  0   *Biphenyl Compounds. Org Lett. 2011 Mar 4;13(5):952-5
2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-methoxybiphenyl-4-yl)ethoxy)-pyrimidin-4-yl)phenyl)propionic acid  0   *Biphenyl Compounds Phenylalanine/*analogs & derivatives Tryptophan Hydroxylase/antagonists & inhibitors. IDrugs 2010 Dec;13(12):921-8
4-methyl-2-cyanobiphenyl  0   *Biphenyl Compounds *Nitriles. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Feb;78(2):590-600
1-biphenyl-4-yl-2-(4-nitrophenoxy)ethanone  0   *Biphenyl Compounds. J Diabetes. 2010 Dec;2(4):282-9
ABD 328  0   *Biphenyl Compounds. Calcif Tissue Int 2010 Dec;87(6):525-32
(R,S)-4-((3-((3,4-dihydroxyphenyl)ethynyl)-4'-hydroxy-4-(hydroxymethyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene)cyclohexa-2,5-dienone  0   *Biphenyl Compounds *Cyclohexanones. J Asian Nat Prod Res. 2011 Feb;13(2):93-6
(R,S)-4-((2',4'-dihydroxy-4-(hydroxymethyl)-3-((4-hydroxyphenyl)ethynyl)biphenyl-2-yl)(4-hydroxyphenyl)methylene)cyclohexa-2,5-dienone  0   *Biphenyl Compounds *Cyclohexanones. J Asian Nat Prod Res. 2011 Feb;13(2):93-6
biphenyldiyl-2,2'-bis(methylphosphonic acid)  0   *Biphenyl Compounds *Phosphonic Acids. Dalton Trans. 2010 Dec 7;39(45):11008-18
carbonyl-(11C)-6-hydroxy-(1,1'-biphenyl)-3-yl cyclohexylcarbamate  0   *Biphenyl Compounds *Carbamates. Chemistry. 2011 Jan 3;17(1):259-64
H128 compound  0   *Biphenyl Compounds *Phenylurea Compounds Diacylglycerol O-Acyltransferase/antagonists & inhibitors. Acta Pharmacol Sin 2010 Nov;31(11):1470-7
2'-carbethoxy-biphenylylmethyl pyrimidinone  0   *Biphenyl Compounds *Pyrimidinones. Pharmazie. 2010 Nov;65(11):794-800
3,4'-dihydroxy-3',5'-dimethoxybiphenyl-4-carboxylic acid  0   *Biphenyl Compounds *Salicylic Acids Monophenol Monooxygenase/antagonists & inhibitors. Bioorg Med Chem 2010 Sep 15;18(18):6708-14
biphenyl-4,4'-diaminium bis(3-carboxy-4-hydroxybenzenesulfonate) dihydrate  0   *Benzenesulfonates *Biphenyl Compounds. Acta Crystallogr C. 2010 Oct;66(Pt 10):o508-12
2-(3-fluoro-3'-methoxybiphenyl-4-carbamoyl)cyclopent-1-enecarboxylic acid  0   *Biphenyl Compounds *Dicarboxylic Acids. Am J Pathol 2010 Jun;176(6):2840-7
6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol  0   *Biphenyl Compounds *Piperazines *Tetrahydronaphthalenes. Bioorg Med Chem. 2010 Aug 1;18(15):5661-74
N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo(d)thiazole-2,6-diamine  0   *Biphenyl Compounds *Piperazines *Thiazoles Receptors, Dopamine D3/agonists. J Neurosci Res. 2010 Aug 15;88(11):2513-23
MK 0674  0   *Biphenyl Compounds Cathepsin K/antagonists & inhibitors. Bioorg Med Chem Lett 2010 Feb 1;20(3):887-92
N-(2-oxo-3-oxetanyl)biphenyl-4-carboxamide  0   *Biphenyl Compounds *Ethers, Cyclic. J Med Chem 2010 Aug 12;53(15):5770-81
4'-(pyridin-4-ylmethyl)biphenyl-3,4-diol  0   *Biphenyl Compounds *Pyridines Steroid 17-alpha-Hydroxylase/antagonists & inhibitors. J Med Chem 2010 Aug 12;53(15):5749-58
4'-(pyridin-4-ylmethyl)biphenyl-3-amine  0   *Biphenyl Compounds *Pyridines Steroid 11-beta-Hydroxylase/antagonists & inhibitors Steroid 17-alpha-Hydroxylase/antagonists & inhibitors. J Med Chem 2010 Aug 12;53(15):5749-58
TAK-070  0   *Biphenyl Compounds *Naphthalenes.
fucotriphlorethol A  0   *Biphenyl Compounds *Phenyl Ethers. Phytochemistry 2010 Feb;71(2-3):221-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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