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Bleomycin

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Definition: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.  a glycopeptide antineoplastic antibiotic   
Pharmacological Action Antibiotics, Antineoplastic
Examples Peplomycin; Phleomycins 		Other names cell pharm Brand of Bleomycin Sulfate; Mack Brand of Bleomycin Sulfate; Lundbeck Brand of Bleomycin Sulfate; Lemery Brand of Bleomycin Sulfate; Bull Brand of Bleomycin Sulfate; Bristol-Myers Squibb Brand of Bleomycin Sulfate; Bl+¬omycine Bellon; Bleomycinum Mack; Bleomycins; Bleomycin Sulfate; Bleomycin B2; Bleomycin B(2); Bleomycin A2; Bleomycin A(2); Bleomicina; Bleolem; Blenoxane; Blanoxan; Bellon Brand of Bleomycin Sulfate; BLEO-cellDrugs* : BLEOMYCIN SULFATE; BLENOXANE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
boningmycin  0   Bleomycin/*analogs & derivatives Antibiotics, Antineoplastic. Anticancer Drugs. 2011 Feb;22(2):166-75
NC 0604  0   *Bleomycin. Oncol Rep 2010 Sep;24(3):629-35
tallysomycin H-1  0   Bleomycin/*analogs & derivatives. Appl Microbiol Biotechnol 2010 May;86(5):1345-53
COPP-ABVD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Dacarbazine Doxorubicin Prednisone Procarbazine Vinblastine Vincristine. Pediatr Blood Cancer 2007 Aug;49(2):139-44
BOVAPEC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Prednisolone Vinblastine Vincristine. Vnitr Lek. 2007 Jan;53(1):31-7
MOPPEBVCAD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Doxorubicin/*analogs & derivatives Lomustine Mechlorethamine Melphalan Prednisone Procarbazine Vinblastine Vincristine Vindesine. J Clin Oncol. 2005 Dec 20;23(36):9198-207
ABVG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Deoxycytidine/*analogs & derivatives Doxorubicin Vinblastine. Cancer. 2003 Sep 1;98(5):978-82
BEMOP-CA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Methotrexate Prednisolone Vincristine. Int J Oncol 2003 Feb;22(2):421-4
BOP-CISCA-POMB-ACE regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Cyclophosphamide Dactinomycin Doxorubicin Etoposide Methotrexate Vincristine. Br J Cancer 2002 May 20;86(10):1555-60
VEPA-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin/analogs & derivatives Prednisolone Vincristine. Int J Hematol 2002 Jan;75(1):67-71
BEMP protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Vindesine Mitomycin. Ann Oncol 2001 Jul;12(7):967-74
BMC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Lomustine Methotrexate. Gynecol Oncol 2001 Jun;81(3):348-54
bleomycin A5 glycoconjugate  0   Bleomycin/*analogs & derivatives. Org Lett 2001 May 3;3(9):1291-4
LBCMVD-56 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Chlorambucil Dexamethasone Lomustine Methotrexate Vincristine. Ann Oncol. 2000 Jul;11(7):857-60
BAP protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Dactinomycin. Oncol Rep. 2000 Nov-Dec;7(6):1235-8
EBVD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Dacarbazine Vinblastine Epirubicin. Leuk Lymphoma 2000 Mar;37(1-2):131-43
VBVP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Prednisone Vinblastine. J Clin Oncol 2000 Apr;18(7):1500-7
CEVBP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Prednisolone Vincristine Epirubicin. J Korean Med Sci 1999 Oct;14(5):565-70
m-BOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Ifosfamide Methotrexate Vincristine. Ann Oncol 1999 Jun;10(6):685-92
HM 91 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Methotrexate Prednisone Vinblastine Vincristine. Blood 1998 Nov 15;92(10):3591-8
PACEBO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Prednisolone Vincristine. Clin Lab Haematol 1998 Apr;20(2):119-21
CAPABLE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Cyclophosphamide Doxorubicin Methotrexate. J Clin Oncol 1998 Jul;16(7):2514-21
nitrosyl iron(II) bleomycin  0   *Bleomycin *Ferrous Compounds. Nucleic Acids Symp Ser 1997;(37):99-100
VIP-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Etoposide Ifosfamide. J Clin Oncol 1998 Feb;16(2):692-701
CIOP-Bleo protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Prednisone Vincristine Idarubicin. Anticancer Drugs 1997 Nov;8(10):937-42
CAB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Doxorubicin. Otolaryngol Pol 1995;49 Suppl 20:287-91
COPEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin/analogs & derivatives Cyclophosphamide Etoposide Prednisone Vincristine. Chung Hua Chung Liu Tsa Chih 1996 May;18(3):227-9
PMitCEBO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Etoposide Mitoxantrone Prednisolone Vincristine. Acta Oncol 1997;36(6):573-6
THP-COPBLM regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin/analogs & derivatives Prednisone Procarbazine Vincristine Granulocyte Colony-Stimulating Factor. Leukemia 1997 Nov;11(11):1817-20
VICOP-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Etoposide Prednisone Vincristine Idarubicin. Haematologica 1997 May-Jun;82(3):309-13
VBM protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Methotrexate Vinblastine. J Clin Oncol 1997 May;15(5):1736-44
Zeocin  181494-14-4   *Bleomycin. Trends Biochem Sci 1997 Mar;22(3):105-6
ABOD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Dacarbazine Doxorubicin Vincristine. Acta Oncol 1996;35(Suppl 8):73-80
NCVB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Mitoxantrone Vincristine. J Clin Oncol 1997 Mar;15(3):1131-7
ABVDP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Dacarbazine Doxorubicin Prednisone Vinblastine. Leuk Lymphoma 1996 Mar;21(1-2):79-84
CODBLAM IV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Dexamethasone Doxorubicin Procarbazine Vincristine. Am J Clin Oncol 1997 Feb;20(1):90-6
BVMM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Methotrexate Mitolactol Vincristine. Neoplasma 1996;43(1):51-6
VIP-VB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Etoposide Ifosfamide Vinblastine. Am J Clin Oncol 1996 Oct;19(5):487-91
CHV-mP-VB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Prednisone Vincristine. Blood 1996 May 15;87(10):4358-67
cadmium bleomycin  0   Bleomycin/*analogs & derivatives Organometallic Compounds Cadmium. Biochemistry 1996 Feb 6;35(5):1458-65
zinc bleomycin  0   *Organometallic Compounds Bleomycin/*analogs & derivatives Zinc. Biochemistry 1996 Feb 6;35(5):1458-65
P-COMM-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Methotrexate Mitoxantrone Prednisolone Vincristine. Leuk Lymphoma 1995 Jun;18(1-2):137-43
ProMECE-CytaBOM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Cytarabine Etoposide Methotrexate Prednisone Vincristine Epirubicin. Haematologica 1995 Sep-Oct;80(5):416-20
LNH 87 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Prednisone Vindesine. Blood 1996 Jan 1;87(1):265-72
bleomycin A5-pd(CCAAACA)  0   *Bleomycin *Oligodeoxyribonucleotides. Nucleic Acids Res 1995 Nov 11;23(21):4400-6
MINE-BOP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Ifosfamide Mitoxantrone Prednisone Vincristine. Acta Oncol 1995;34(7):937-40
POMB-ACE regimen  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Cyclophosphamide Dactinomycin Etoposide Methotrexate Vincristine. Gan To Kagaku Ryoho 1995 Oct;22(12):1847-50
technetium Tc 99m pingyangmycin  0   *Bleomycin *Organotechnetium Compounds. Nucl Med Biol 1995 May;22(4):537-42
CVPPABO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Prednisone Procarbazine Vinblastine Vincristine. Blood 1995 Jul 15;86(2):451-6
VECABOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Prednisone Procarbazine Vinblastine Vincristine. Blood 1995 Jul 15;86(2):451-6
Stanford V protocol  0   Bleomycin *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Etoposide Mechlorethamine Prednisone Vinblastine Vincristine. J Clin Oncol 1995 May;13(5):1080-8
PACE-BOM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Etoposide Methotrexate Prednisolone Vincristine. Clin Lab Haematol 1994 Dec;16(4):355-7
M-BACOS protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Doxorubicin Methotrexate Methylprednisolone Hemisuccinate Vincristine. Blood 1995 May 1;85(9):2516-20
CEOP-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Prednisone Vincristine Epirubicin. J Clin Oncol 1995 Apr;13(4):953-60
VIMB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Ifosfamide Mitoxantrone. J Clin Oncol 1995 Apr;13(4):953-60
m-BECOD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Leucovorin Cyclophosphamide Dexamethasone Methotrexate Vincristine Epirubicin. Leuk Lymphoma 1994 Sep;15(1-2):153-7
MVPP-Bleo protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Mitoxantrone Prednisone Procarbazine Vincristine. Leuk Lymphoma 1994 Sep;15(1-2):153-7
ECBC protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cisplatin Cyclophosphamide Etoposide. Br J Cancer 1994 Nov;70(5):960-5
VEBEP regimen  0   Bleomycin *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Etoposide Prednisone Epirubicin. Int J Radiat Oncol Biol Phys 1994 Nov 15;30(4):813-9
bleomycin-mannan conjugate  0   *Mannans Bleomycin/*analogs & derivatives. Biol Pharm Bull 1994 May;17(5):748-52
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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