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Boronic Acids

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Definition: Inorganic or organic compounds that contain the basic structure RB(OH)2.  do not confuse with BORINIC ACIDS    Other names Acids, Boronic
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
boroalanine  0   *Boronic Acids Alanine/*analogs & derivatives. Chem Biol Drug Des. 2011 Nov;78(5):757-63.
2-amino-6-borono-2-(difluoromethyl)hexanoic acid  0   *Amino Acids *Boronic Acids Arginase/antagonists & inhibitors. J Med Chem 2011 Aug 11;54(15):5432-43
2-amino-6-borono-2-methylhexanoic acid  0   *Amino Acids *Boronic Acids Arginase/antagonists & inhibitors. J Med Chem 2011 Aug 11;54(15):5432-43
1,4-phenylenebis(boronic acid)  0   *Boronic Acids. Science. 2011 Apr 8;332(6026):228-31
8-isoquinolinylboronic acid  0   *Boronic Acids *Isoquinolines Fluorescent Dyes. Chemistry. 2010 Dec 3;16(45):13528-38
1-(3-(3-fluorophenyl)-3-(1,2,3,4-tetrahydronaphthalene-4-carboxamido)propanamido)-3-methylbutyl boronic acid  0   *Boronic Acids. J Med Chem 2010 Dec 23;53(24):8619-26
dutogliptin  852329-66-9   *Boronic Acids. Curr Med Res Opin. 2010 Aug;26(8):2003-10
2-(hexadecyloxy)-naphthalene-6-boronic acid  0   *Boronic Acids *Naphthalenes. Talanta 2010 Apr 15;81(1-2):591-6
poly(3-acrylamidophenylboronic acid-co-ethylene dimethacrylate)  0   *Acrylic Resins *Boronic Acids. Analyst 2009 Oct;134(10):2158-64
(isonicotinic acid (2-(4,4,5,5-tetramethyl-(1,3,2)dioxaborolan-2-yl)benzylidene)hydrazide)  0   *Boronic Acids *Isonicotinic Acids. J Inorg Biochem 2008 Dec;102(12):2130-5
2-bromopyridine-5-boronic acid  0   *Boronic Acids *Pyridines. Anal Biochem. 2009 Mar 15;386(2):186-93
poly(acrylamide-ran-3-acrylamidophenylboronic acid)  0   *Acrylic Resins *Boronic Acids. Biomacromolecules 2009 Jan 12;10(1):113-8
thiophene-3-boronic acid  0   *Boronic Acids *Thiophenes. Anal Chem. 2008 Nov 1;80(21):8035-44
2-formylphenylboronic acid  0   *Benzaldehydes *Boronic Acids. Nat Protoc 2008;3(2):210-4
(1-(((1-(1-oxo-2-N-((phenylmethoxy)carbonyl)-3-phenylpropyl)pyrrolidin-2-yl)carbonyl)amino)-4-methoxybutyl)-1-boronic acid  0   *Boronic Acids *Dipeptides. J Extra Corpor Technol 2008 Jun;40(2):116-22
CEP-18770  0   *Boronic Acids Threonine/*analogs & derivatives Proteasome Endopeptidase Complex/antagonists & inhibitors. Blood 2008 Mar 1;111(5):2765-75
benzo(b)thiophene-2-ylboronic acid  0   *Boronic Acids *Thiophenes beta-Lactamases/antagonists & inhibitors. J Med Chem 2007 Nov 15;50(23):5644-54
pinacolyl allylboronate  0   *Alkenes *Boronic Acids *Butanes. Angew Chem Int Ed Engl 2007;46(31):5909-12
N-isopropylacrylamide-co-acrylamidophenylboronic acid  0   *Acrylamides *Boronic Acids. J Phys Chem B 2006 Oct 19;110(41):20635-9
4-pyridineboronic acid  0   *Boronic Acids *Pyridines. Dalton Trans 2007 Jun 7;(21):2121-6
3-pyridineboronic acid  0   *Boronic Acids *Pyridines. Dalton Trans 2007 Jun 7;(21):2121-6
3-amino-1-(1-boronic-ethyl)pyrrolidine-2-one  0   *Boronic Acids *Pyrrolidinones.
Pharma Action Dipeptidyl-Peptidase IV Inhibitors
J Med Chem 2007 May 17;50(10):2391-8
4-(2-(anthracen-10-yloxy)ethoxycarbonyl)phenylboronic acid  0   *Anthracenes *Boronic Acids. Bioorg Med Chem Lett 2007 Jan 1;17(1):94-6
talabostat  0   *Boronic Acids *Dipeptides Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/antagonists & inhibitors. Drug News Perspect 2006 Jun;19(5):299
poly(AAPBA-DMAA)  0   *Acrylic Resins *Boronic Acids. Eur Cell Mater 2006;12() (dup#1):36-43
3,5-bis(4-boronic acid-benzylidene)-1-methylpiperidin-4-one  0   *Boronic Acids *Piperidines. Bioorg Med Chem 2006 May 15;14(10):3491-5
beta-(4-borono-2,6-difluorophenyl)alaninol  0   *Boronic Acids Phenylalanine/*analogs & derivatives. Bioorg Med Chem 2006 May 15;14(10):3258-62
beta-(4-borono-2,6-difluorophenyl)alanine  0   *Boronic Acids Phenylalanine/*analogs & derivatives. Bioorg Med Chem 2006 May 15;14(10):3258-62
polyvinylamine-poly(4-carboxyphenylboronic acid)  0   *Boronic Acids *Polyvinyls. Biomacromolecules 2006 Mar;7(3):701-2
dithiobis(4-butyrylamino-m-phenylboronic acid)  0   *Boronic Acids *Sulfhydryl Compounds. Langmuir. 2005 May 24;21(11):5101-7
4-mercaptophenylboronic acid  0   *Boronic Acids *Sulfhydryl Compounds. Langmuir. 2005 May 24;21(11):5101-7
N-(4-morpholine)carbonyl-beta-(1-naphthyl)-alanyl-leucine boronic acid  0   *Boronic Acids *Dipeptides. Mol Microbiol 2006 Mar;59(5):1417-28
3-(4-(3-phenyl-2-pyrazolin-1-yl)benzene-1-sulfonylamido)phenylboronic acid  0   *Boronic Acids *Sulfonamides Myosins/antagonists & inhibitors. Biochemistry 2006 Jan 31;45(4):1234-41
N-(o-boronic acid)benzyl-1-naphthylamine  0   *Boronic Acids 1-Naphthylamine/*analogs & derivatives. Luminescence 2005 Jul-Oct;20(4-5):331-3
4-(4,5-diphenyl-1H-imidazol-2-yl)phenylboronic acid  0   *Boronic Acids *Imidazoles. J Chromatogr A. 2005 Feb 25;1066(1-2):119-25
thiolate boronic acid  0   *Boronic Acids *Sulfhydryl Compounds. Anal Biochem 2004 Sep 15;332(2):253-60
4-carboxy-3-fluorophenylboronic acid  0   *Boronic Acids. Clin Chem 2004 Dec;50(12):2353-60
4-amino-3-fluorophenylboronic acid  0   *Boronic Acids. Clin Chem 2004 Dec;50(12):2353-60
2-methylphenyl boronic acid  0   *Boronic Acids. Angew Chem Int Ed Engl. 2004 Mar 26;43(14):1871-6
dansyl-3-aminophenylboronate  0   *Boronic Acids *Dansyl Compounds. Rapid Commun Mass Spectrom. 2004;18(7):816-21
4-(dimethylamino)naphthalene-1-boronic acid  0   *Boronic Acids 1-Naphthylamine/*analogs & derivatives. Org Lett 2003 Nov 27;5(24):4599-602
3-((1-((4-(5,6-dimethoxy-1-oxoisoindolin-2-yl)-2-methoxyphenyl)sulfonyl)pyrrolidin-2-yl)carbonylamino)phenylboronic acid  0   *Boronic Acids *Pyrrolidines. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 25;788(2):401-5
8-quinolineboronic acid  0   *Boronic Acids *Quinolines. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1019-22
PT-100 dipeptide  0   *Boronic Acids *Dipeptides. Blood. 2003 Sep 1;102(5):1641-8
thianaphthene-2-boronic acid  0   *Boronic Acids *Thiophenes. J Med Chem 2003 Jul 31;46(16):3448-51
alanyl-boroalanine  0   *Boronic Acids *Dipeptides. Adv Exp Med Biol 2003;524:333-8
4'-cyanostilbene-4-boronic acid  0   *Boronic Acids *Stilbenes Fluorescent Dyes. Anal Biochem 2002 Feb 1;301(1):111-6
glutamyl-gamma-boronate  0   *Boronic Acids Glutamates. Bioorg Med Chem Lett 2001 Sep 17;11(18):2561-4
Phe-Leu boronic acid  0   *Boronic Acids *Dipeptides. Transplantation 2001 Jul 27;72(2):196-202
tolylboronic acid  0   *Boronic Acids. Org Lett 2001 Jun 28;3(13):2077-9
4-(4,5-di(2-pyridyl)-1H-imidazol-2-yl)phenylboronic acid  0   *Boronic Acids. Luminescence 2001 Mar-Apr;16(2):167-72
4-vinylphenyl boronic acid  0   *Boronic Acids *Vinyl Compounds. J Biomater Sci Polym Ed 2000;11(8):817-31
(2-boronoethyl)-cysteine  0   *Boronic Acids Arginase/antagonists & inhibitors. Biochemistry 2001 Mar 6;40(9):2678-88
MG 262  0   *Boronic Acids. Proc Natl Acad Sci U S A 2001 Jan 16;98(2):513-8
3-acrylamidophenylboronic acid  0   *Boronic Acids. Biotechnol Bioeng 2001 Feb 5;72(3):307-14
1-aminocyclopropaneboronic acid  0   *Boronic Acids *Cyclopropanes Protease Inhibitors. Org Lett 2000 Oct 5;2(20):3095-7
1-acetamido-2-(3-carboxy-2-hydroxyphenyl)ethylboronic acid  0   *Boronic Acids. Biochemistry 2000 May 9;39(18):5312-21
1-phenylacetamido-2-(3-carboxyphenyl)ethylboronic acid  0   *Boronic Acids. Biochemistry 2000 May 9;39(18):5312-21
diisopropyl 2-bora-2-(3-(phenyldimethylsilyl)-2-propen-1-yl)-1,3-dioxole-4,5-dicarboxylate  0   *Boronic Acids *Organosilicon Compounds. Org Lett 2000 Feb 24;2(4):461-4
4-boronic acid benzophenone  0   *Benzophenones *Boronic Acids Subtilisin/antagonists & inhibitors. Bioorg Med Chem 2000 Mar;8(3):563-70
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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