encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 

Buprenorphine

More information in Books or onNLM PubMed
Definition: A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.  for buprenorphine maintenance treatment, coordinate with OPIATE SUBSTITUTION TREATMENT   
Pharmacological Action Analgesics, Opioid; Narcotic Antagonists; Narcotics
See Also Opiate Substitution Treatment 		Other names Schering Plough Brand of Buprenorphine Hydrochlori; RX 6029 M; Hydrochloride, Buprenorphine; RX6029M; Buprenorphine Gr++nenthal Brand; 6029M; 6029 M; Temg+Žsic; Temgesic; Subutex; Schering-Plough Brand of Buprenorphine Hydrochlori; Reckitt Brand of Buprenorphine Hydrochloride; Reckitt Benckiser Brand of Buprenorphine Hydrochlo; Reckitt & Colman Brand 2 of Buprenorphine Hydrochl; Reckitt & Colman Brand 1 of Buprenorphine Hydrochl; RX-6029-M; Prefin; Key Brand of Buprenorphine Hydrochloride; Gr++nenthal Brand of Buprenorphine Hydrochloride; Gr++nenthal Brand of BuprenorphineDrugs* : BUTRANS; SUBUTEX; BUPRENEX; BUPRENORPHINE HYDROCHLORIDE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl)-3,3-dimethylpentan-2-ol  0   Buprenorphine/*analogs & derivatives Ligands Receptors, Opioid. J Pharmacol Exp Ther 2011 Mar;336(3):952-61
thienorphine  0   Buprenorphine/*analogs & derivatives. J Pharmacol Exp Ther. 2006 Jul;318(1):282-7
suboxone  0   *Buprenorphine *Naloxone Drug Combinations. Am J Addict 2006 Jan-Feb;15(1):1-7SUBOXONE
norbuprenorphine-3-beta-D-glucuronide  0   Buprenorphine/*analogs & derivatives. J Mass Spectrom 2005 Jan;40(1):70-4
thenorphine  0   Buprenorphine/*analogs & derivatives. Acta Pharmacol Sin. 2004 Nov;25(11):1413-8
HS 599  0   Buprenorphine/*analogs & derivatives. Br J Pharmacol 2001 Sep;134(2):441-7
BU 48  0   Buprenorphine/*analogs & derivatives. J Pharmacol Exp Ther 2000 Sep;294(3):1195-200
N-(3-fluoropropyl)-N-norbuprenorphine  128837-83-2   Buprenorphine/*analogs & derivatives. Int J Rad Appl Instrum (B) 1990;17(2):217
buprenorphine-3-O-glucuronide  101224-22-0   Buprenorphine/*analogs & derivatives. Ann Clin Biochem 1986;23(Pt 1):47
norbuprenorphine  78715-23-8   Buprenorphine/*analogs & derivatives. Drug Metab Dispos 1984;12(5):577
demethoxybuprenorphine  91423-89-1 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-alpha-methyl-, (5alpha,7alpha(S))  Buprenorphine/*analogs & derivatives. J Pharmacol Exp Ther 1984;229(3):768

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy