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Butylene Glycols

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Definition: 4-carbon straight chain aliphatic hydrocarbons substituted with two hydroxyl groups. The hydroxyl groups cannot be on the same carbon atom.     
Examples Busulfan 		Other names Dihydroxybutanes; Butanediols; Glycols, Butylene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
hydroxyphenamate  50-19-1   *Butylene Glycols *Carbamates Anti-Anxiety Agents. Dent Dig. 1970 Feb;76(2):112-3
3,4-dihydroxy-3-methylpentan-2-one  0   *Butylene Glycols. PLoS One. 2009;4(5) (dup#16):e5627
threoninol  0   *Amino Alcohols *Butylene Glycols. J Med Chem 1994 Oct 28;37(22):3749-57
2-(N,N-dibenzylamino)butane-1,3-diol  0   *Benzylamines *Butylene Glycols. Acta Crystallogr C 2008 Jan;64(Pt 1):o18-20
1,4-bis(thymin-1-yl)butane-2,3-diol  0   *Butylene Glycols Thymine/*analogs & derivatives. Org Biomol Chem 2008 Jan 7;6(1):81-91
poly(tetrahydrofuran)  0   *Butylene Glycols *Polymers. Biomacromolecules 2007 Sep;8(9):2916-27
3,4-epoxy-1,2-butanediol  0   *Butylene Glycols. Chem Biol Interact 2007 Mar 20;166(1-3):182-90
1-(hypoxanth-1-yl)-4-(guan-7-yl)-2,3-butanediol  0   *Butylene Glycols *Hypoxanthines. Chem Res Toxicol. 2007 Feb;20(2):284-9
1,4-bis(2'-deoxyadenosin-N(6)-yl)-2S,3S-butanediol  0   *Butylene Glycols *Deoxyadenosines. Chem Res Toxicol. 2007 Feb;20(2):187-98
1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol  0   *Butylene Glycols. Bioorg Med Chem. 2006 Nov 1;14(21):7075-82
1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol  0   *Butylene Glycols. Bioorg Med Chem. 2006 Nov 1;14(21):7075-82
2-methyl-1,2-butanediol  41051-72-3   *Butylene Glycols. Phytochem Anal 2002 Nov-Dec;13(6):329-32
1,3-butane-diepoxide-2,3-diol  0   *Butylene Glycols. N Engl J Med 2002 Dec 12;347(24):(1980-2; author reply 1980-2; discussion 1980-2)
1,3-butane-diene-2,3-diol  0   *Butylene Glycols. N Engl J Med 2002 Dec 12;347(24):(1980-2; author reply 1980-2; discussion 1980-2)
1,3-butanediol diacetoacetate  0   *Acetoacetates *Butylene Glycols. Am J Physiol 1995 Jul;269(1 Pt 1):E67-75
1,3-butanediol 1-monoacetoacetate  0   *Acetoacetates *Butylene Glycols. Am J Physiol 1995 Jul;269(1 Pt 1):E67-75
1,3-butanediol 3-monoacetoacetate  0   *Acetoacetates *Butylene Glycols. Am J Physiol 1995 Jul;269(1 Pt 1):E67-75
1,4-bis-(4-(3-iodo-4-methoxyphenyl)butylamino)butane-2,3-diol  0   *Butylene Glycols. Arch Pharm (Weinheim) 1995 May;328(5):465-7
secoisolariciresinol diglucoside  148244-82-0   *Butylene Glycols *Glucosides. Rapid Commun Mass Spectrom 1994 Aug;8(8):595-8
bionole  0   *Butylene Glycols *Polymers. Eisei Shikenjo Hokoku 1993;(111):25-33
1,4-di-(4-hydroxyphenyl)-2,3-butanediol  150346-21-7   *Butylene Glycols *Phenols Stereoisomerism Streptomyces. J Antibiot (Tokyo) 1993 May;46(5):756-61
diolmycin A1  150408-69-8   *Butylene Glycols *Indoles Stereoisomerism Streptomyces. J Antibiot (Tokyo) 1993 May;46(5):756-61
1,4-butanediol divalproate  77656-73-6   *Butylene Glycols Valproic Acid/*analogs & derivatives. Biopharm Drug Dispos 1993 Jan;14(1):51-9
secoisolariciresinol  29388-59-8   *Butylene Glycols *Lignans.
Pharma Action Phytoestrogens 		Clin Chim Acta 1989;180(3):293
2-methyl-2,3-butanediol  5396-58-7 2,3-Butanediol, 2-methyl  *Butylene Glycols. Clin Chim Acta 1987;165(2-3):197
penitricin C  110-64-5   *Butylene Glycols. J Antibiot (Tokyo) 1984;37(7):718
1,4-butanediol  110-63-4   *Butylene Glycols. Toxicology 1984;29(3):261
1,3-butylene glycol  107-88-0   *Butylene Glycols. J Pharmacol Exp Ther 1981;216(2):306
phenaglycodol  79-93-6   *Butylene Glycols. Farmaco (Prat) 1980;35(11):564
2,3-butylene glycol  513-85-9   *Butylene Glycols. Adv Exp Med Biol 1980;132:229
butanediol diacrylate  1070-70-8 2-propenoic acid, 1,4-butanediyl ester  *Butylene Glycols. Contact Dermatitis 5(3):178;1979
2,4-dihydroxybutyrate  1518-62-3 2,4-dihydroxybutanoic acid  *Butylene Glycols *Butyric Acids. J Biol Chem 254(23):11969;1979
1,3-butanediol-1,3-dioctanoate  4554-00-1 Octanoic acid, 1-methyl-1,3-propanediyl ester  *Butylene Glycols. J Nutr 109(3):473;1979
3,4-dihydroxybutyrate  0   *Butylene Glycols *Butyric Acids. Biochem Med 17(3):284;1977
1,4-bis(2,3-epoxypropoxy)butane  2425-79-8 2,2'-(1,4-butanediylbis(oxymethylene)bisoxirane)  *Butylene Glycols. Anal Biochem 81:98;1977; Eur J Biochem 1980;103(2):421; J Chromatogr 135(2):427;1977
3,4-dihydroxybutyl-1-phosphonic acid  37636-10-5   *Butylene Glycols *Phosphonic Acids. J Bacteriol 129(1):550;1977; JBC 251(21):6717;1976
4-methylthiobutane-1,2-diol  57070-84-5 1,2-Butanediol, 4-(methylthio)  *Butylene Glycols. J Agric Food Chem 23(6):1137;1975
2-butyne-1,4-diol  110-65-6   *Butylene Glycols. J Pharm Pharmac 26(8):597;1974
butylene glycol adipic acid polyester  52012-76-7   *Butylene Glycols *Polymers Plasticizers. Toxicol Appl Pharmacol 26(1):58;1973
erythro-alpha,beta-dihydroxybutyraldehyde  6045-85-8   *Butylene Glycols. Boll Ist Sieroter Milan 52(1):5;1973; Cancer Res 38(7):2180;1978
4-(4-nitrophenoxy)-1,2-butanediol  0   *Butylene Glycols. Anal Biochem 52(1):198;1973
dibromobutenediol  3234-02-4   *Butylene Glycols.
butanediol divinylether  3891-33-6   *Butylene Glycols *Ethers. Europ J Biochem 25(1):129;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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