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Carbon Radioisotopes

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Definition: Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes.  C-10,11,14-16; NIM; /blood-csf-urine /metab permitted but not for tracer studies (    Other names Radioisotopes, CarbonDrugs* : MERETEK UBT KIT (W/ PRANACTIN); PYTEST KIT; PYLORI-CHEK BREATH TEST; BREATHTEK UBT FOR H-PYLORI; HELICOSOL; PYTEST; IDKIT:HP
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GSK215083  0   *Quinolines *Sulfones Carbon Radioisotopes. J Nucl Med. 2012 Feb;53(2):295-303.
GSK 1034702  0   *Benzimidazoles Carbon Radioisotopes Receptor, Muscarinic M1/agonists. Appl Radiat Isot. 2011 Oct;69(10):1390-4.
3-(2'-fluoro-6',7'-dihydrospiro(piperidine-4,4'-thieno(3,2-c)pyran)-1-yl)-2-(2-fluorobenzyl)-N-methylpropanamide  0   *Spiro Compounds *Bicyclo Compounds, Heterocyclic Carbon Radioisotopes Ligands. J Nucl Med 2011 Oct;52(10):1638-45
4-(5-(1-methyl-1H-pyrrol-2-yl)-1,3,4-oxadiazol-2-yl)-1,4-diazabicyclo(3.2.2)nonane  0   *Oxadiazoles *Azabicyclo Compounds Carbon Radioisotopes Ligands. J Nucl Med 2011 Sep;52(9):1449-56
ketoprofen methyl ester  0   Ketoprofen/*analogs & derivatives Carbon Radioisotopes. J Nucl Med 2011 Jul;52(7):1094-101
N-((1-((5-(4-fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide  0   *Benzofurans *Thiazoles Carbon Radioisotopes. Drug Metab Dispos 2011 Feb;39(2):215-27
7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine  0   *Naphthyridines *Pyridazines Carbon Radioisotopes. Chem Res Toxicol 2010 Nov 15;23(11):1743-52
2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine  0   *Benzylamines *Phenethylamines Carbon Radioisotopes Ligands Receptor, Serotonin, 5-HT2A. J Nucl Med 2010 Nov;51(11):1763-70
16-m-tolyl-17,18-,19-,20-tetranorisocarbacyclin methyl ester  0   *Bicyclo Compounds *Pentanoic Acids Carbon Radioisotopes. J Pharmacol Exp Ther 2010 Nov;335(2):314-23
(1-butylpiperidin-4-yl)methyl 4-amino-3-methoxybenzoate  0   4-Aminobenzoic Acid/*analogs & derivatives Carbon Radioisotopes Ligands Receptors, Serotonin, 5-HT4. J Med Chem 2010 Oct 14;53(19):7035-47
methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)aminocarbonyl)-2-(quinoline-2-carbonylamino)benzoate  0   *Benzoates *Quinolines Carbon Radioisotopes. Nucl Med Biol 2010 Jul;37(5):637-44
2-(3-fluorotolyl)-4,5-dihydro-1H-imidazole  0   *Imidazoles Carbon Radioisotopes. Nucl Med Biol 2010 Jul;37(5):625-35
BMS-690514  0   *Piperidines *Pyrroles *Triazines Carbon Radioisotopes. Br J Cancer. 2010 Jul 27;103(3):347-53
N-((benzofuran-2-yl)methyl)-N'-(4'-methoxybenzyl)piperazine  0   *Benzofurans *Piperazines Carbon Radioisotopes Ligands Receptors, sigma. J Med Chem 2010 Aug 26;53(16):6228-39
(N-methyl-(11)C) 5-methyl-3-(4-(3-phenylallyl)-piperazin-1-ylmethyl)-3,3a,4,5-tetrahydroisoxazolo(4,3-c)quinoline  0   *Isoxazoles *Quinolines Carbon Radioisotopes. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3654-7
2-chloro-N-n-propylnorapomorphine  0   Apomorphine/*analogs & derivatives Carbon Radioisotopes Ligands Receptors, Dopamine D2/agonists. Nucl Med Biol 2010 Jan;37(1):35-40
N-methyl-hydroxyfasudil  0   1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/*analogs & derivatives Carbon Radioisotopes. Appl Radiat Isot 2010 Feb;68(2):325-8
5-methoxy-N-methyl-3-oxo-N-(2-piperidin-1-ylethyl)-3H-spiro(2-benzofuran-1,1'-cyclohexane)-4'-carboxamide  0   *Benzofurans *Piperidines Carbon Radioisotopes Receptors, Histamine H3. Synapse 2009 Dec;63(121):1122-32
N-benzyl-N-methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide  0   *Acetamides *Purines Carbon Radioisotopes. Nucl Med Biol. 2009 Oct;36(7):801-9
6-bromo-7-methylpurine  0   *Purines Carbon Radioisotopes. J Med Chem 2009 Nov 26;52(22):7284-8
PR04.MZ compound  0   *Tropanes Carbon Radioisotopes. Bioorg Med Chem Lett 2009 Aug 1;19(15):4343-5
iodoacetanilide  0   *Acetanilides Carbon Radioisotopes. Bioorg Med Chem Lett 2009 Oct 1;19(19):5698-702
N-(2-(3-cyanophenyl)-3-(4-(2-methoxy)phenyl)-1-methylpropyl)-2-(5-methyl-2-pyridyloxy)-2-methylpropanamide  0   *Amides *Pyridines Carbon Radioisotopes Ligands. Mol Imaging Biol 2009 Jul-Aug;11(4):246-52
phenylethyl orvinol  0   *Morphinans Carbon Radioisotopes Receptors, Opioid, mu/agonists Receptors, Opioid, kappa/agonists. J Med Chem 2009 Sep 24;52(18):5586-9
N-(4-fluorobenzyl)-4-(3-(piperidin-1-yl)indole-1-sulfonyl)benzamide  0   *Benzamides *Indoles *Piperidines Carbon Radioisotopes Fluorine Radioisotopes. Synapse. 2009 Jan;63(1):22-30
SB 207145  0   *Piperidines Carbon Radioisotopes Ligands. J Cereb Blood Flow Metab 2009 Jan;29(1):186-96
CHIBA 1001  0   *Bicyclo Compounds, Heterocyclic Carbon Radioisotopes. PLoS ONE 2008;3(9):e3231
7-hydroxy-N-(1-((4-(3-hydroxyphenyl)-3,4-dimethyl-1--piperidinyl)methyl)-2-methylpropyl)-1,2,3,4-tetrahydro-2-methylisoquinolinecarboxamide  0   *Piperidines *Tetrahydroisoquinolines Carbon Radioisotopes. Nucl Med Biol 2008 Jul;35(5):561-9
3-(3-(3-trifluoropropylthio)-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine  0   *Pyridines *Thiadiazoles Carbon Radioisotopes. Nucl Med Biol 2008 Apr;35(3):287-98
1-(1-methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone  0   *Pyrroles *Pyrrolidines Carbon Radioisotopes. J Med Chem 2008 Mar 27;51(6):1617-22
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5-(2H,4H)-dione  0   *Piperazines *Triazines Carbon Radioisotopes Receptor, Serotonin, 5-HT1A/agonists. Eur J Nucl Med Mol Imaging 2007 Jul;34(7):1050-60
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-iodobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-bromobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-fluorobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
3-(2'-deoxyribofuranosyl)-6-(4-methoxyphenyl)-2,3-dihydrofuro(2,3-d)pyrimidin-2(3H)-one  0   *Pyrimidine Nucleosides Carbon Radioisotopes. J Med Chem 2007 Dec 27;50(26):6627-37
N-acetyl-N-(2-methoxycarbonylbenzyl)-2-phenoxyaniline  0   *Acetanilides *Benzoates Carbon Radioisotopes. J Med Chem 2008 Jan 10;51(1):17-30
(methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine  0   *Pyrimidines Carbon Radioisotopes. J Nucl Med. 2007 Dec;48(12):2072-9
5-(3-methoxyphenyl)-3-(1-phenylethylamino)-1-(4-trifluoromethylphenyl)pyrrolidin-2-one  0   *Pyrrolidinones Carbon Radioisotopes. Neuropsychopharmacology 2008 Jan;33(2):259-69
benzoyl-tyrosyl-alanine  0   *Dipeptides Carbon Radioisotopes. Pancreas 2007 Nov;35(4):313-9
2-(6-chloro-2-(4-iodophenyl)-imidazo(1,2-alpha)pyridin-3-yl)-N-ethyl-N-methyl-acetamide  0   *Acetamides *Pyridines Carbon Radioisotopes. Glia. 2007 Nov 1;55(14):1459-68
N,N-dimethyl-4-(6-(methylthio)imidazo(1,2-a)pyridine-2-yl)aniline  0   *Aniline Compounds *Bicyclo Compounds, Heterocyclic Carbon Radioisotopes Ligands. Nucl Med Biol 2007 Aug;34(6):681-9
O-methyl reboxetine  0   *Morpholines Carbon Radioisotopes. Nucl Med Biol 2007 Aug;34(6):667-79
6-chloro-3-(((1-methyl)-2-pyrrolidinyl)methoxy)-5-(2-fluoropyridin-4-yl)pyridine  0   *Pyridines *Pyrrolidines Carbon Radioisotopes. Appl Radiat Isot 2007 Aug;65(8):947-51
R 121920  0   *Pyrazoles *Pyrimidines Carbon Radioisotopes. Nucl Med Biol 2007 May;34(4):353-61
4-hydroxyphenethylguanidine  0   *Guanidines Carbon Radioisotopes. J Med Chem 2007 May 3;50(9):2078-88
3-methoxy-5-pyridin-2-ylethynylpyridine  0   *Pyridines Carbon Radioisotopes. Nucl Med Biol. 2006 Nov;33(8):1021-7
4-fluoro-2-(3,4-dimethoxyphenyl)benzothiazole  0   *Benzothiazoles Carbon Radioisotopes. Bioorg Med Chem 2006 Dec 15;14(24):8599-607
2-carbomethoxy-3-(3'-(2-bromoethenyl)phenyl)nortropane  0   *Nortropanes Carbon Radioisotopes. J Med Chem 2006 Nov 16;49(23):6760-7
2-carbomethoxy-3-(3'-(2-iodoethenyl)phenyl)nortropane  0   *Nortropanes Carbon Radioisotopes. J Med Chem 2006 Nov 16;49(23):6760-7
4-cyano-1-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide  0   *Piperidines *Pyrazoles Carbon Radioisotopes. J Nucl Med 2006 Oct;47(10):1689-96
2, 3, 4, 5, 6, 7-hexahydro-1(4-(1(4-(2-methoxyphenyl)-piperazinyl))-2-phenylbutyry)-1H-azepine  0   *Azepines *Piperazines Carbon Radioisotopes. Synapse. 2006 Dec 1;60(7):510-20
2,5-dimethyl-4-benzoquinonediimine  0   *Imines Carbon Radioisotopes. Chem Res Toxicol 2006 Sep;19(9):1248-56
2-butyl-5-(4-hydroxyphenyl)-5,6,11,11a-tetrahydro-1H-imidazo(1',5'-1,6)pyrido(3,4-b)indole-1,3(2H)-dione  0   *Carbolines Carbon Radioisotopes. Nucl Med Biol 2006 Jul;33(5):593-7
(3-(4-(bis(2-chloroethyl)amino)phenyl)-3-propyl)carbamic acid 2-(6-(17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-11-yl)hexylamino)ethyl ester  0   *Nitrogen Mustard Compounds *Steroids Carbon Radioisotopes. Mol Cancer Ther 2006 Apr;5(4):977-84
N-methyl-2-(4'-methylaminophenyl)-6-hydroxybenzothiazole  0   *Benzothiazoles Carbon Radioisotopes. Neurology. 2006 Aug 8;67(3):446-52
N,N-dimethyl-2-(2-amino-4-methylthiophenylthio)benzylamine  0   *Sulfides *Aniline Compounds Carbon Radioisotopes. Nucl Med Biol 2006 Jan;33(1):53-63
3-(6-methylpyridin-2-ylethynyl)cyclohex-2-enone-O-methyloxime  0   *Oximes *Pyridines Carbon Radioisotopes Receptors, Metabotropic Glutamate/antagonists & inhibitors. J Nucl Med 2006 Apr;47(4):698-705
2-(4-(4-(7-methoxynaphthalen-1-yl)piperazin-1-yl)butyl)-4-methyl-2H-(1,2,4)triazine-3,5-dione  0   *Piperazines *Triazines Carbon Radioisotopes Ligands Receptor, Serotonin, 5-HT1A/agonists. J Med Chem 2006 Jan 12;49(1):125-34
N-(1-(((cyanomethyl)amino)carbonyl)cyclohexyl)-4-(2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl)benzamide  0   *Benzamides *Thiazoles Carbon Radioisotopes. J Med Chem 2005 Dec 1;48(24):7520-34
methyl 4'-O-methylcellobioside  0   Cellobiose/*analogs & derivatives Carbon Radioisotopes. Carbohydr Res 2005 Oct 31;340(15):2428-35
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