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Cardiolipins

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Definition: Acidic phospholipids composed of two molecules of phosphatidic acid covalently linked to a molecule of glycerol. They occur primarily in mitochondrial inner membranes and in bacterial plasma membranes. They are the main antigenic components of the Wassermann-type antigen that is used in nontreponemal SYPHILIS SERODIAGNOSIS.     
See Also Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Syphilis Serodiagnosis 		Other names Diphosphatidylglycerols; Cardiolipin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tetramyristoyl cardiolipin  0   *Cardiolipins. Chem Phys Lipids. 2008 Mar;152(1):13-23
tetralinoleoylcardiolipin  0   *Cardiolipins. J Lipid Res 2007 Jul;48(7):1559-70
1,1',2,2'-tetraoleoylcardiolipin  0   *Cardiolipins. Biochemistry 2007 Mar 20;46(11):3423-34
NEO 6002  0   *Cardiolipins Deoxycytidine/*analogs & derivatives. Anticancer Drugs 2006 Jan;17(1):53-61
glucopyranosylcardiolipin  0   *Cardiolipins. Biochim Biophys Acta 2000 Feb 15;1463(2):307-22
lysylcardiolipin  0   *Cardiolipins. Int J Syst Bacteriol 1999 Apr;49 Pt 2:653-62
alanylcardiolipin  0   *Cardiolipins. J Bacteriol 1998 Jun;180(11):2950-7
2'-deoxycardiolipin (diphosphatidyl-1,3-propanediol)  99018-93-6   *Cardiolipins. Biophim Biophys Acta 1991;1066(2):166
monolysocardiolipin  0   *Cardiolipins *Lysophospholipids. J Lipid Res 1990;31(8):1513
dilysocardiolipin  0   *Cardiolipins *Lysophospholipids. J Lipid Res 1990;31(8):1513
1,2-dipalmitoyloxypropyl-3-(2'-hydroxypropyl-3'-(1'',2''-dipalmitoylglycerol))biphosphonate  119206-59-6   *Cardiolipins *Diphosphonates. Chem Phys Lipids 1988;46(4):253
VDRL antigen  0   *Cardiolipins *Cholesterol *Phosphatidylcholines. J Infect Dis 1988;157(1):23
adriamycin-cardiolipin complex  0   *Cardiolipins *Doxorubicin. Biochemistry 1987;26(6):1789
collarein  89286-72-6 Collarein  *Cardiolipins *Rhodamines. Biochim Biophys Acta 1984;769(1):88

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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